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methyl (1S,4aS,5aS,6S,10aS)-5'-methoxy-1-methyl-2'-oxospiro[1,4a,5,5a,7,8,10,10a-octahydropyrano[3,4-f]indolizine-6,3'-1H-indole]-4-carboxylate

PubChem CID: 21586657

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Compound Synonyms SCHEMBL1652366
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 77.1
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule True
Scaffold Graph Level CC1CC2CCCCC2C12CCC1CC3CCCCC3CC12
Np Classifier Class Corynanthe type
Deep Smiles COcccccc6)[C@]CCN[C@H]5C[C@H][C@@H]C6)[C@H]C)OC=C6C=O)OC))))))))))))))C=O)N5
Heavy Atom Count 29.0
Classyfire Class Indolizidines
Scaffold Graph Node Level OC1NC2CCCCC2C12CCN1CC3COCCC3CC12
Isotope Atom Count 0.0
Molecular Complexity 739.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 5.0
Iupac Name methyl (1S,4aS,5aS,6S,10aS)-5'-methoxy-1-methyl-2'-oxospiro[1,4a,5,5a,7,8,10,10a-octahydropyrano[3,4-f]indolizine-6,3'-1H-indole]-4-carboxylate
Veber Rule True
Classyfire Superclass Organoheterocyclic compounds
Xlogp 1.6
Gsk 4 400 Rule True
Molecular Formula C22H26N2O5
Scaffold Graph Node Bond Level O=C1Nc2ccccc2C12CCN1CC3COC=CC3CC12
Inchi Key HSEWZVYXOFZIMV-IHGKUHQXSA-N
Silicos It Class Moderately soluble
Rotatable Bond Count 3.0
Synonyms palmirine
Esol Class Soluble
Functional Groups CN(C)C, COC(=O)C(C)=COC, cNC(C)=O, cOC
Compound Name methyl (1S,4aS,5aS,6S,10aS)-5'-methoxy-1-methyl-2'-oxospiro[1,4a,5,5a,7,8,10,10a-octahydropyrano[3,4-f]indolizine-6,3'-1H-indole]-4-carboxylate
Exact Mass 398.184
Formal Charge 0.0
Monoisotopic Mass 398.184
Hydrogen Bond Acceptor Count 6.0
Molecular Weight 398.5
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 5.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C22H26N2O5/c1-12-15-10-24-7-6-22(17-8-13(27-2)4-5-18(17)23-21(22)26)19(24)9-14(15)16(11-29-12)20(25)28-3/h4-5,8,11-12,14-15,19H,6-7,9-10H2,1-3H3,(H,23,26)/t12-,14-,15-,19-,22-/m0/s1
Smiles C[C@H]1[C@@H]2CN3CC[C@@]4([C@@H]3C[C@@H]2C(=CO1)C(=O)OC)C5=C(C=CC(=C5)OC)NC4=O
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Hamelia Patens (Plant) Rel Props:Reference:https://doi.org/10.15482/usda.adc/1239279