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Tokorogenin

PubChem CID: 20841762

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Compound Synonyms Tokorogenin, (25R)-5beta-spirostan-1beta,2beta,3alpha-triol, CHEBI:186718, LMST01080027, (1S,2S,4S,5'R,6R,7S,8R,9S,12S,13S,14S,15R,16S,18R)-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icosane-6,2'-oxane]-14,15,16-triol
Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 79.2
Hydrogen Bond Donor Count 3.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC2(CC1)CC1CC3C(CCC4C5CCCCC5CCC43)C1C2
Np Classifier Class Spirostane steroids
Deep Smiles C[C@@H]CC[C@@]OC6))O[C@@H][C@H][C@@H]5C))[C@@][C@@H]C5)[C@@H]CC[C@H][C@][C@H]6CC%10)))C)[C@H]O)[C@@H][C@H]C6)O))O)))))))))C
Heavy Atom Count 32.0
Classyfire Class Prenol lipids
Scaffold Graph Node Level C1CCC2(CC3C(CC4C3CCC3C5CCCCC5CCC34)O2)OC1
Classyfire Subclass Triterpenoids
Isotope Atom Count 0.0
Molecular Complexity 758.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 14.0
Iupac Name (1S,2S,4S,5'R,6R,7S,8R,9S,12S,13S,14S,15R,16S,18R)-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icosane-6,2'-oxane]-14,15,16-triol
Prediction Hob 0.0
Veber Rule True
Classyfire Superclass Lipids and lipid-like molecules
Xlogp 4.5
Gsk 4 400 Rule False
Molecular Formula C27H44O5
Scaffold Graph Node Bond Level C1CCC2(CC3C(CC4C3CCC3C5CCCCC5CCC34)O2)OC1
Prediction Swissadme 0.0
Inchi Key SRTGQBIWSBCVSM-RXWDRLOESA-N
Silicos It Class Soluble
Fcsp3 1.0
Logs -4.403
Rotatable Bond Count 0.0
Logd 4.251
Synonyms tokorogenin
Esol Class Moderately soluble
Functional Groups CO, CO[C@@](C)(C)OC
Compound Name Tokorogenin
Prediction Hob Swissadme 0.0
Exact Mass 448.319
Formal Charge 0.0
Monoisotopic Mass 448.319
Hydrogen Bond Acceptor Count 5.0
Molecular Weight 448.6
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 14.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -5.481792800000001
Inchi InChI=1S/C27H44O5/c1-14-7-10-27(31-13-14)15(2)22-21(32-27)12-19-17-6-5-16-11-20(28)23(29)24(30)26(16,4)18(17)8-9-25(19,22)3/h14-24,28-30H,5-13H2,1-4H3/t14-,15+,16-,17-,18+,19+,20+,21+,22+,23-,24-,25+,26+,27-/m1/s1
Smiles C[C@@H]1CC[C@@]2([C@H]([C@H]3[C@@H](O2)C[C@@H]4[C@@]3(CC[C@H]5[C@H]4CC[C@H]6[C@@]5([C@@H]([C@@H]([C@H](C6)O)O)O)C)C)C)OC1
Nring 6.0
Np Classifier Biosynthetic Pathway Terpenoids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Steroids

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  • 2. Outgoing r'ship FOUND_IN to/from Dioscorea Tenuipes (Plant) Rel Props:Source_db:npass_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Dioscorea Tokoro (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 4. Outgoing r'ship FOUND_IN to/from Huperzia Serrata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 5. Outgoing r'ship FOUND_IN to/from Hydrangea Chinensis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 6. Outgoing r'ship FOUND_IN to/from Lupinus Mutabilis (Plant) Rel Props:Source_db:npass_chem_all
  • 7. Outgoing r'ship FOUND_IN to/from Melicope Semecarpifolia (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all