Allantoin
PubChem CID: 204
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| Compound Synonyms | allantoin, 97-59-6, 5-Ureidohydantoin, Glyoxyldiureide, 1-(2,5-dioxoimidazolidin-4-yl)urea, Cordianine, Glyoxyldiureid, Allantol, Alantan, Sebical, AVC/Dienestrolcream, Urea, (2,5-dioxo-4-imidazolidinyl)-, Psoralon, Septalan, Hydantoin, 5-ureido-, Cutemol emollient, (2,5-Dioxo-4-imidazolidinyl)urea, Uniderm A, (2,5-dioxoimidazolidin-4-yl)urea, Glyoxylic(acid) diureide, DL-Allantoin, Glyoxylic diureide, NSC 7606, 5-Ureido-2,4-imidazolidindion, Alwextin, Caswell No. 024, CCRIS 1958, 2,5-Dioxo-4-imidazolidinyl-urea, N-(2,5-Dioxo-4-imidazolidinyl)urea, EPA Pesticide Chemical Code 085701, 4-ureido-2,5-Imidazolidinedione, Idelalisib metabolite m1a, AI3-15281, NSC-7606, Fancol TOIN, 5-Ureidohydrantoin, EINECS 202-592-8, MFCD00005260, BRN 0102364, (+/-)-Allantoin, 5-Ureido-2,4-imidazolidindione, DTXSID3020043, UNII-344S277G0Z, CHEBI:15676, HSDB 7490, NSC7606, Allantoin (JAN/USP), N-(2,5-dioxoimidazolidin-4-yl)urea, 344S277G0Z, 97-59-6 (racemic), DTXCID0043, MLS000737882, 5377-33-3, Sd 101, Allantoin [USAN:USP:BAN:JAN], EC 202-592-8, 5-25-15-00338 (Beilstein Handbook Reference), DL-ALLANTOIN-5-13C, 1-15N, urea, N-(2,5-dioxo-4-imidazolidinyl)-, ALLANTOIN (II), ALLANTOIN [II], Herpecin L, ALLANTOIN (MART.), ALLANTOIN [MART.], D00121, ALLANTOIN (USP-RS), ALLANTOIN [USP-RS], ALLANTOIN (EP MONOGRAPH), ALLANTOIN [EP MONOGRAPH], ALLANTOIN (USP MONOGRAPH), ALLANTOIN [USP MONOGRAPH], Allantoin (USAN:USP:BAN:JAN), C4H6N4O3, Allantoin [USAN:BAN], SMR000528073, SR-01000766252, Alantoina, Scarderm, Teevodar, Purple, ScarEquate, Allantoin Cream, Mulberry Serum, Mulberry Toner, Chamois Glide, Scar Reducer, Sol Mouthwash, HealingCVS, Cool Melon, Equate Scar, Kenaf wet wipe, Polyactil N, Scar Cream, Scar Care, Anti Chafe Balm, Meijer Scar Gel, Mulberry Emulsion, Scar Gel, Bruise MD, Mederma for Kids, ScarCVS, Rite Aid Scar, Vitamin C Liquid, BL Vital Serum, AC Control Serum, BL Vital, BL Vital Essence, BL Vital Skin, CAS-97-59-6, Equate ScarTopical, Advanced Scar Gel, Bodyglide For Her, Prestwick_11, NCGC00016358-01, Allation,(S), DCH Scar, Diabetic Wound Gel, QC Scar, Run Guard Original, U-max Multi BB, 5-ureido-Hydantoin, Allantoin (8CI), Allantoin .4%, Burn-B Gone OTC, GMDANSU Skin, Run Guard Sensitive, Kenaf wet wipe kids, Allantoin 0.5%, Allantoin-0.5%, Advanced Derma Spray, ARC Skin Protectant, ATOBOS, HAHALADY, NAAMAN, Sarene Soothing Skin, Seaweed Aqua Massage, SEUK, Smart Brushing Tooth, The Prestige Essence, Ultra Soothing Toner, VASHTI, Healing Head to Toe, Allantoin (Standard), GMDANSU Eye Serum, Pelo Baum Brow Brow, Pelo Baum Lash Lash, Mederma Advanced Scar, Mandelic 2 Peel Gel, RAPHAGENPOWDE R, SOOSUL ESSENCE, ALRA THERAPY, ATOBOS WASH, MIRACLE GYN, Advanced Derma Therapy, Wound Gel Professional, FUCOIDAN ESSENCE, Lycoris rubus whitening, NoblRose Foam Cleanser, Version X Scalp Tonic, DOG MX BANDAGE, First honey Burn Salve, NEWSTEM Rx Intensive, Spectrum_001078, REVAGAIN Scalp Tonic, FUCOIDAN SKINCURE, ALLANTOIN [JAN], ALLANTOIN [MI], Jilgyungyi (6 Tablets), PORE CARE Lotus Mask, Scar GelAdvanced Formula, ALLANTOIN [HSDB], ALLANTOIN [USAN], Bodyglide anti chafe balm, Prestwick0_000002, Prestwick1_000002, Prestwick2_000002, Prestwick3_000002, Spectrum2_000219, Spectrum3_000876, Spectrum4_000716, Spectrum5_001526, Target Advanced Scar Gel, ALLANTOIN [VANDF], Nano Gold Bio Mask Pack, Baby Wipes with Allantoin, Drs. pharmacy Scar Cream, SBS 41 Medicated Cream, ECO FACE 9, Jilgyungyi (10 Tablets), BLACK CAVIDIOL MASK, FUCOIDAN HAIR TONIC, Gene 16 Whitening Factor, REBORNCELL CLEANSING, bmse000437, OHL O2, Anti-Chafe StickPro Series, ALLANTOIN [WHO-DD], Calm and Heal Melting Balm, Miracle GYN (2 Tablets), Miracle GYN (4 Tablets), SCHEMBL3208, Cetaphil Soothing Gel Cream, GMDANSU Herbal Mask Sheet, Pelo Baum Hair Revitalizing, Rite Aid Advanced Scar Gel, Sheffield Advanced Scar Gel, Walgreens Advanced Scar Gel, BIOWHITE BEAUTY SERUM, DR DEEP AQUA WRINKLE, OZ TREEHandMade by Dorothy, Secret Gyno (10 Tablets), Shelo NABEL D B T Cream, Oprea1_621175, Tamnamo Vital Hair Treatment, BSPBio_000003, BSPBio_002551, KBioGR_001271, KBioSS_001558, Miracle GYN (10 Tablets), Shelo NABEL Jabon Baba Car, SISEUNDEUSI BLESS BODY, VetraCare Pet Liquid Bandage, Dr. Dog Skin Care for Dogs, Luxury Cell Performance Serum, Luxury Cell Performance Toner, M-Rose Seaweed Essence Serum, M-Rose Seaweed Hydrogel Mask, MLS002473300, Shelo NABEL Baba de Caracol, Well and Good Liquid Bandage, Allantoin, analytical standard, DivK1c_000281, SPECTRUM1500801, CVS Health Advanced Scar Gel, Macoma Senior Premium Cleanser, Queen Perfume Hair Conditioner, SPBio_000237, SPBio_001924, Cellpium vampire cleansing mask, Dermaheal Ultimatum PTx Sports, Lycoris RUBUS Whitening Fluid, BPBio1_000005, CHEMBL593429, Diabetic Wound Gel Professional, Hasol Revitalizing Scalp Ampoule, Inflammation OTCRadiation Relief, Luxury Cell Performance Emulsion, SD 101 [WHO-DD], 5-Ureidohydantoin, Glyoxyldiureide, ATOBOS BABY AQUA SOOTHING, HAIRJOY MSM SCALP ESSENCE, HMS500O03, HY-N0543R, KBio1_000281, KBio2_001558, KBio2_004126, KBio2_006694, KBio3_002051, REBORNCELL AQUA RICH SOFT, VET WORTHY LIQUID BANDAGE, Vital Fluid IV Nano Gold Serum, Allantoin, >=98.0% (N), Parma Anus Skin Premium Cleanser, PLAGENTRA BABY BUBBLE WASH, Leaders Mediu Purifying Salt Pack, NINDS_000281, Urea,5-dioxo-4-imidazolidinyl)-, Dr Deep Brightening FacialEmulsion, HMS1568A05, HMS1921I10, HMS2092K16, HMS2095A05, HMS2268N08, HMS3712A05, HMS3885M08, LUMINANT UMBRELLA MASK PACK, Pharmakon1600-01500801, Fikia Marine Delight Soothing Mist, Shelo NABEL CACAO Skin Protectan, U-max Whitening Functional Essence, 3CE FIXER AND MASCARA BLACK, 3CE FIXER AND MASCARA BROWN, BCP31832, Blister Armour Anti-FrictionMission, component of Skin-balm (Salt/Mix), HY-N0543, Lycoris rubus whitening moisturizing, M-Rose Seaweed Lifting Revitalizing, PHYTON THERAPY CLEANSING BAR, Ramosu The Witches Cream Pack Gold, Shelo NABEL Crema Baba de Caracol, UYB40251, 2,5-Imidazolidinedione, 4-ureido-, Cellapy MGF Hydro Gel Intense Mask, Tox21_110395, Tox21_202087, Tox21_302912, BBL027508, CCG-39781, IASOBETIC Allantoin Skin Protectant, NSC757792, s3856, STL373778, BK Cell 2STEP AQUA TOKTOK MASK, REBORNCELL AQUA RICH PURE SKIN, AKOS000120642, AKOS016038547, Dr Young 2p Blemish Base SPF35 PA, Skin Barista Rice Bran Cleansing Foam, Tox21_110395_1, 1ST2594, By Pharmicell Lab The Prestige Essence, Cetaphil Baby Soothe and Protect Cream, CS-7741, DB11100, FA01871, NSC-757792, SDCCGMLS-0066595.P001, IDI1_000281, USEPA/OPP Pesticide Code: 085701, Allantoin, p.a., 98.5-101.0%, IONTOPHORESISANTI AGING SOLUTION I, N-(2,5-Dioxo-4-imidazolidinyl)urea #, NCGC00094854-01, NCGC00094854-02, NCGC00094854-03, NCGC00094854-04, NCGC00094854-05, NCGC00094854-06, NCGC00094854-07, NCGC00094854-08, NCGC00256403-01, NCGC00259636-01, (RS)-(2,5-dioxoimidazolidin-4-yl)urea, AC-11040, AS-13865, NCI60_041675, Scar ReducerIntensive Herbal and Nutrient, DGH Advanced Formula Scar Skin Protectant, QYO QYO Tangerine Bright Moist Mask Pack, SBI-0051759.P002, Vital Fluid I Platinum Anti Wrinkle Serum, Leaders Mediu Pore Cleaning Carbonated Pack, NOBLESSE MANZ GROOMING SO CLEAN CARE, A0211, AB00052307, BIOXIDEA ELEMENT 48 NATURA GOLD MASK, HAIRFILL SCALP HAIR ESSENTIAL BOOSTER, LEADERS MEDIU CALMING PEPPERMINT PACK, NS00009152, Shelo NABEL Baba de Caracol Locion Corporal, Vital Fluid II EGF and FGF Whitening Serum, EN300-21043, SECRETIPSS SCALP HAIR ESSENTIAL BOOSTER, BIOXIDEA ELEMENT 48 NATURA DIAMOND MASK, C01551, D85069, HAIRFILL SCALP HAIR ESSENTIAL TONIC PLUS, Urea, (2,5-dioxo-4-imidazolidinyl)- (9CI), AB00052307_11, BIOXIDEA MIRACLE 48 EXCELLENCE GOLD MASK, By Pharmicell Lab Luxury Cell Performance Serum, By Pharmicell Lab Luxury Cell Performance Toner, By Pharmicell Lab Moisturizing Face Toning Mist, Dr. Young 2P Pearl Brightening Balm SPF35 PA, Jabon Shelo Nabel Con Alantoina Baba de Caracol, By Pharmicell Lab Luxury Cell Performance Emulsion, Q409804, SECRETIPSS SCALP HAIR ESSENTIAL TONIC PLUS, BIOXIDEA MIRACLE 48 EXCELLENCE DIAMOND MASK, HYUNDAE MEDITECH BIO HAIR SOLU TION ERUA DO, ORIGINAL POWER WHITENING AND LINELESS AMPOULE, SkinCeuticals Advanced Scar Control Skin Protectant, SR-01000766252-2, SR-01000766252-3, SR-01000766252-4, BRD-A96407378-001-15-1, N-(2,5-dihydroxy-4h-imidazol-4-yl) carbamimidic acid, Z104486690, Allantoin, European Pharmacopoeia (EP) Reference Standard, NANOMIX NANO CLEANSkin Protectant Antibacterial Function, A999F0D6-0285-41D9-A6BA-B705987B663C, Allantoin, United States Pharmacopeia (USP) Reference Standard, BOTANETH PRONOXIN HAIR REGAINER FS2 ACTIVATOR 2-A 2-B, Allantoin, Pharmaceutical Secondary Standard, Certified Reference Material, SECRETIPSS SCALP HAIR ESSENTIAL BOOSTERINTENSE CARE FOR DAMAGED SCALPS AND HAIRS, 202-592-8, 5-Ureidohydantoin, Glyoxyldiureide, Glyoxylic diureide, Cordianine, Glyoxyldiureid, (2,5-Dioxo-4-imidazolidinyl)urea |
|---|---|
| Ghose Rule | False |
| Classyfire Kingdom | Organic compounds |
| Topological Polar Surface Area | 113.0 |
| Hydrogen Bond Donor Count | 4.0 |
| Pfizer 3 75 Rule | True |
| Scaffold Graph Level | CC1CCC(C)C1 |
| Np Classifier Class | Purine alkaloids |
| Deep Smiles | NC=O)NCNC=O)NC5=O |
| Heavy Atom Count | 11.0 |
| Classyfire Class | Azoles |
| Description | Allantoin is a chemical compound with formula C4H6N4O3. It is also called 5-ureidohydantoin or glyoxyldiureide. It is a diureide of glyoxylic acid. Named after the allantois, an amniote embryonic excretory organ in which it concentrates during development in most mammals except humans and higher apes, it is a product of oxidation of uric acid by purine catabolism. After birth, it is the predominant means by which nitrogenous waste is excreted in the urine of these animals. In humans and higher apes, the metabolic pathway for conversion of uric acid to allantoin is not present, so the former is excreted. Recombinant rasburicase is sometimes used as a drug to catalyze this metabolic conversion in patients. In fish, allantoin is broken down further (into ammonia) before excretion. Allantoin is a major metabolic intermediate in many other organisms including plants and bacteria., Its chemical formula is C4H6N4O3. It is also called 5-ureidohydantoin, glyoxyldiureide, and 5-ureidohydantoin. It is a product of oxidation of uric acid. It is a diureide of glyoxylic acid. It is a product of purine metabolism in most mammals except higher apes, and it is present in their urine. Allantoin is a botanical extract of the comfrey plant and is used for its healing, soothing, and anti-irritating properties. Allantoin helps to heal wounds and skin irritations and stimulate growth of healthy tissue. This extract can be found in anti-acne products, sun care products, and clarifying lotions because of its ability to help heal minor wounds and promote healthy skin. |
| Scaffold Graph Node Level | OC1CNC(O)N1 |
| Classyfire Subclass | Imidazoles |
| Isotope Atom Count | 0.0 |
| Molecular Complexity | 225.0 |
| Database Name | cmaup_ingredients;fooddb_chem_all;hmdb_chem_all;imppat_phytochem;npass_chem_all;pubchem |
| Defined Atom Stereocenter Count | 0.0 |
| Uniprot Id | A6NGE7, O14924, P11473, P37840, Q9NPD5, Q9Y6L6, P27695, n.a., P34897, P10275 |
| Iupac Name | (2,5-dioxoimidazolidin-4-yl)urea |
| Prediction Hob | 0.0 |
| Class | Azoles |
| Veber Rule | True |
| Classyfire Superclass | Organoheterocyclic compounds |
| Target Id | NPT2969 |
| Xlogp | -2.2 |
| Superclass | Organoheterocyclic compounds |
| Subclass | Imidazoles |
| Gsk 4 400 Rule | True |
| Molecular Formula | C4H6N4O3 |
| Scaffold Graph Node Bond Level | O=C1CNC(=O)N1 |
| Prediction Swissadme | 0.0 |
| Inchi Key | POJWUDADGALRAB-UHFFFAOYSA-N |
| Silicos It Class | Soluble |
| Fcsp3 | 0.25 |
| Logs | -3.03 |
| Rotatable Bond Count | 1.0 |
| State | Solid |
| Logd | -0.643 |
| Synonyms | (+/-)-allantoin, (2,5-Dioxo-4-imidazolidinyl)urea, 1-(2,5-dioxoimidazolidin-4-yl)urea, 2,5-Dioxo-4-imidazolidinyl-urea, 2,5-Imidazolidinedione, 4-ureido-, 4-ureido-2,5-Imidazolidinedione, 5-Ureido-2,4-imidazolidindion, 5-ureido-Hydantoin, 5-Ureidohydantoin, 5-Ureidohydrantoin, Alantan, Allantoin (8CI), Allantoin (jan/usp), Allantoin [usan:ban], Allantoin campbell brand, Allantoin sween brand, Allantol, Alloxantin, Campbell brand of allantoin, Cordianine, Cutemol emollient, DL-allantoin, Fancol toin, Glyoxyldiureid, Glyoxyldiureide, Glyoxylic diureide, Glyoxylic(acid) diureide, Hemocane, Herpecin l, Herpecin-l, Herpecinl, Hydantoin, 5-ureido-, N-(2,5-Dioxo-4-imidazolidinyl)urea, N-(2,5-dioxoimidazolidin-4-yl)urea, N-[2,5-dioxoimidazolidin-4-yl]urea, Paxyl, Psoralon, Reed & carnrick brand of allantoin, Sebical, Septalan, Skin strategies for men-soothing moisturizer, Sween brand of allantoin, Uniderm a, Urea, (2, 5-dioxo-4-imidazolidinyl)-, Urea, (2,5-dioxo-4-imidazolidinyl)-, Urea, (2,5-dioxo-4-imidazolidinyl)- (9CI), Urea, N-(2,5-dioxo-4-imidazolidinyl)-, Ureidohydantoin, Woun'dres, 4-Ureido-2,5-imidazolidinedione, 5-Ureido-2,4-imidazolidindione, (S)-Allantoin, 5-Ureido-hydantoin, AVC/Dienestrolcream, D00121, Sween brand OF allantoin, Herpecin-L, HerpecinL, Reed and carnrick brand OF allantoin, Campbell brand OF allantoin, Herpecin L, allantoin, allqntoin, dl-allantoin |
| Esol Class | Highly soluble |
| Functional Groups | NC(=O)NC1NC(=O)NC1=O |
| Compound Name | Allantoin |
| Kingdom | Organic compounds |
| Prediction Hob Swissadme | 0.0 |
| Exact Mass | 158.044 |
| Formal Charge | 0.0 |
| Monoisotopic Mass | 158.044 |
| Hydrogen Bond Acceptor Count | 3.0 |
| Molecular Weight | 158.12 |
| Gi Absorption | False |
| Covalent Unit Count | 1.0 |
| Total Atom Stereocenter Count | 1.0 |
| Total Bond Stereocenter Count | 0.0 |
| Molecular Framework | Aliphatic heteromonocyclic compounds |
| Lipinski Rule Of 5 | True |
| Esol | -0.19692540000000014 |
| Inchi | InChI=1S/C4H6N4O3/c5-3(10)6-1-2(9)8-4(11)7-1/h1H,(H3,5,6,10)(H2,7,8,9,11) |
| Smiles | C1(C(=O)NC(=O)N1)NC(=O)N |
| Nring | 1.0 |
| Np Classifier Biosynthetic Pathway | Alkaloids |
| Defined Bond Stereocenter Count | 0.0 |
| Egan Rule | False |
| Taxonomy Direct Parent | Imidazoles |
| Np Classifier Superclass | Pseudoalkaloids |
- 1. Outgoing r'ship
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FOUND_INto/from Symphytum Officinale (Plant) Rel Props:Reference:https://www.ncbi.nlm.nih.gov/pubmed/25880800 - 58. Outgoing r'ship
FOUND_INto/from Triticum Aestivum (Plant) Rel Props:Source_db:cmaup_ingredients;fooddb_chem_all;npass_chem_all - 59. Outgoing r'ship
FOUND_INto/from Vigna Mungo (Plant) Rel Props:Source_db:fooddb_chem_all - 60. Outgoing r'ship
FOUND_INto/from Vitellaria Paradoxa (Plant) Rel Props:Source_db:fooddb_chem_all - 61. Outgoing r'ship
FOUND_INto/from Wisteria Sinensis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all - 62. Outgoing r'ship
FOUND_INto/from Zea Mays (Plant) Rel Props:Source_db:cmaup_ingredients;fooddb_chem_all;npass_chem_all