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Kopsine

PubChem CID: 20054949

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Compound Synonyms Kopsine, Kopsine [MI], (-)-Kopsine, Kopsine, (-)-, 559-48-8, 9999HLB81M, UNII-9999HLB81M, 3-Hydroxy-22-oxokopsan-1-carboxylic acid methyl ester, Kopsan-1-carboxylic acid, 3-hydroxy-22-oxo-, methyl ester, 6H,13Ah-3a,5a-ethano-5,11-methano-1H-indolizino(8,1-cd)carbazole-6-carboxylic acid, 2,3,4,5,11,12-hexahydro-5-hydroxy-14-oxo-, methyl ester, (3aR,5S,5aS,10bR,11R,13aS)-, methyl (1R,4S,12R,13S,16R,18S)-18-hydroxy-17-oxo-5,14-diazaheptacyclo[12.5.3.01,13.04,12.04,18.06,11.012,16]docosa-6,8,10-triene-5-carboxylate, methyl (3aR,3a1S,5S,5aS,10bR,11R)-5-hydroxy-14-oxo-2,3,4,5,11,12-hexahydro-1H,3a1H,6H-3a,5a-ethano-5,11-methanoindolizino[8,1-cd]carbazole-6-carboxylate, Methyl 3-hydroxy-22-oxokopsan-1-carboxylate, SCHEMBL23064406, Q27272188
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 70.1
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1C2CC34CCCC5CC1C1(C6CCCCC6CC21CC3)C54
Np Classifier Class Aspidosperma type
Deep Smiles COC=O)Ncccccc6[C@][C@]9CC[C@]C[C@@]6O)C=O)[C@H]9CN[C@H]%128)CCC%10
Heavy Atom Count 28.0
Classyfire Class Aspidofractine alkaloids
Scaffold Graph Node Level OC1C2CC34CCCN5CC1C1(C6CCCCC6NC21CC3)C54
Isotope Atom Count 0.0
Molecular Complexity 816.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 6.0
Iupac Name methyl (1R,4S,12R,13S,16R,18S)-18-hydroxy-17-oxo-5,14-diazaheptacyclo[12.5.3.01,13.04,12.04,18.06,11.012,16]docosa-6,8,10-triene-5-carboxylate
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 1.3
Gsk 4 400 Rule True
Molecular Formula C22H24N2O4
Scaffold Graph Node Bond Level O=C1C2CC34CCCN5CC1C1(c6ccccc6NC21CC3)C54
Inchi Key YROYAGSZNDUMIF-MQVQQYNVSA-N
Silicos It Class Soluble
Rotatable Bond Count 1.0
Synonyms kopsine
Esol Class Soluble
Functional Groups CC(C)=O, CN(C)C, CO, cN(C)C(=O)OC
Compound Name Kopsine
Exact Mass 380.174
Formal Charge 0.0
Monoisotopic Mass 380.174
Hydrogen Bond Acceptor Count 5.0
Molecular Weight 380.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 6.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C22H24N2O4/c1-28-18(26)24-15-6-3-2-5-13(15)22-14-11-23-10-4-7-19(17(22)23)8-9-21(22,24)20(27,12-19)16(14)25/h2-3,5-6,14,17,27H,4,7-12H2,1H3/t14-,17+,19-,20-,21-,22+/m1/s1
Smiles COC(=O)N1C2=CC=CC=C2[C@@]34[C@]15CC[C@]67[C@@H]3N(CCC6)C[C@@H]4C(=O)[C@@]5(C7)O
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Kopsia Fruticosa (Plant) Rel Props:Reference:ISBN:9788172360481