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Alstovenine

PubChem CID: 199742

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Compound Synonyms Alstovenine, Isovenenatine, 4837-79-0, 3-Isovenenatine, methyl (1S,15S,18R,19S,20S)-18-hydroxy-8-methoxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate, AKOS040752133, Yohimban-16-carboxylic acid, 17-hydroxy-9-methoxy-, methyl ester, (16-beta,17-beta,20-alpha)-
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 74.8
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC2CC3C(CCC4C5CCCCC5CC34)CC2C1
Np Classifier Class Yohimbine-like alkaloids
Deep Smiles COC=O)[C@@H][C@H]O)CC[C@H][C@@H]6C[C@@H]NC6)CCcc6[nH]cc5cOC))ccc6
Heavy Atom Count 28.0
Classyfire Class Yohimbine alkaloids
Scaffold Graph Node Level C1CCC2CN3CCC4C5CCCCC5NC4C3CC2C1
Isotope Atom Count 0.0
Molecular Complexity 601.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 5.0
Iupac Name methyl (1S,15S,18R,19S,20S)-18-hydroxy-8-methoxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 2.9
Gsk 4 400 Rule True
Molecular Formula C22H28N2O4
Scaffold Graph Node Bond Level c1ccc2c3c([nH]c2c1)C1CC2CCCCC2CN1CC3
Prediction Swissadme 1.0
Inchi Key WMMZYEBFJWWUJX-IFBQROQASA-N
Silicos It Class Moderately soluble
Fcsp3 0.5909090909090909
Logs -2.825
Rotatable Bond Count 3.0
Logd 2.548
Synonyms alstovenine
Esol Class Moderately soluble
Functional Groups CN(C)C, CO, COC(C)=O, cOC, c[nH]c
Compound Name Alstovenine
Prediction Hob Swissadme 1.0
Exact Mass 384.205
Formal Charge 0.0
Monoisotopic Mass 384.205
Hydrogen Bond Acceptor Count 5.0
Molecular Weight 384.5
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 5.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -4.096908342857144
Inchi InChI=1S/C22H28N2O4/c1-27-18-5-3-4-15-19(18)13-8-9-24-11-12-6-7-17(25)20(22(26)28-2)14(12)10-16(24)21(13)23-15/h3-5,12,14,16-17,20,23,25H,6-11H2,1-2H3/t12-,14+,16+,17-,20+/m1/s1
Smiles COC1=CC=CC2=C1C3=C(N2)[C@@H]4C[C@H]5[C@H](CC[C@H]([C@H]5C(=O)OC)O)CN4CC3
Nring 5.0
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Alstonia Venenata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all