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(-)-Gallocatechin gallate

PubChem CID: 199472

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Compound Synonyms (-)-Gallocatechin gallate, 4233-96-9, (-)-Gallocatechol gallate, (2S,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)chroman-3-yl 3,4,5-trihydroxybenzoate, Gallocatechin gallate, (-)-, [(2S,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate, Gallocatechol, 3-gallate, (-)-, (2S,3R)-2-(3,4,5-Trihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol 3-(3,4,5-trihydroxybenzoate), IRW3C4Y31Q, (-)-Gallocatechin 3-gallate, CCRIS 9286, (-)-gallocatechin-3-O-gallate, L-GCG, MFCD00214298, NVP-XAA 225, CHEMBL264938, (-)-Gallocatechin 3-O-gallate, CHEBI:156271, DTXSID20195144, Benzoic acid, 3,4,5-trihydroxy-, 3,4-dihydro-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-2H-1-benzopyran-3-yl ester, (2S-trans)-, (2S,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate, (2S,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3-yl 3,4,5-trihydroxybenzoate, BENZOIC ACID, 3,4,5-TRIHYDROXY-, (2S,3R)-3,4-DIHYDRO-5,7-DIHYDROXY-2-(3,4,5-TRIHYDROXYPHENYL)-2H-1-BENZOPYRAN-3-YL ESTER, UNII-IRW3C4Y31Q, GCG, ent-Gallocatechin 3-gallate, SCHEMBL49461, CHEBI:95002, HY-N0522R, DTXCID30117635, WMBWREPUVVBILR-NQIIRXRSSA-N, HY-N0522, BDBM50236531, s9058, (-)-Gallocatechin gallate (Standard), AKOS015901852, AC-6044, CCG-269313, CS-7698, FG40482, Gallocatechol, 3-gallate, (-)-(8CI), NCGC00390250-01, 1ST40201, BS-50638, DA-59404, (-)-Gallocatechin gallate, analytical standard, A11681, BRD-K19216856-001-01-9, Q27166763, (-)-Gallocatechin gallate, from green tea, >=98% (HPLC), (2S,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)chroman-3-yl3,4,5-trihydroxybenzoate, (-)-GALLOCATECHIN-3-O-GALLATE (GCG) (CONSTITUENT OF POWDERED DECAFFEINATED GREEN TEA EXTRACT), 636-979-1
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 197.0
Hydrogen Bond Donor Count 8.0
Pfizer 3 75 Rule True
Scaffold Graph Level CC(CC1CC2CCCCC2CC1C1CCCCC1)C1CCCCC1
Np Classifier Class Flavan-3-ols
Deep Smiles OcccO)ccc6)O[C@H][C@@H]C6)OC=O)cccO)ccc6)O))O))))))))cccO)ccc6)O))O
Heavy Atom Count 33.0
Classyfire Class Flavonoids
Description Ent-gallocatechin 3-gallate, also known as (-)-gallocatechol gallic acid, is a member of the class of compounds known as catechin gallates. Catechin gallates are organic compounds containing a gallate moiety glycosidically linked to a catechin. Ent-gallocatechin 3-gallate is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). Ent-gallocatechin 3-gallate can be found in tea, which makes ent-gallocatechin 3-gallate a potential biomarker for the consumption of this food product.
Scaffold Graph Node Level OC(OC1CC2CCCCC2OC1C1CCCCC1)C1CCCCC1
Classyfire Subclass Flavans
Isotope Atom Count 0.0
Molecular Complexity 667.0
Database Name cmaup_ingredients;fooddb_chem_all;hmdb_chem_all;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 2.0
Uniprot Id Q965D7, Q965D5, Q965D6, P11412, P52209, P08581, n.a., P10415, P08238, A0A024AXB9, P28074, P37840
Iupac Name [(2S,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate
Prediction Hob 0.0
Class Flavonoids
Veber Rule False
Classyfire Superclass Phenylpropanoids and polyketides
Target Id NPT1336, NPT1337, NPT980, NPT1429, NPT1187, NPT920
Xlogp 1.2
Superclass Phenylpropanoids and polyketides
Subclass Flavonoid glycosides
Gsk 4 400 Rule False
Molecular Formula C22H18O11
Scaffold Graph Node Bond Level O=C(OC1Cc2ccccc2OC1c1ccccc1)c1ccccc1
Prediction Swissadme 0.0
Inchi Key WMBWREPUVVBILR-NQIIRXRSSA-N
Silicos It Class Soluble
Fcsp3 0.1363636363636363
Logs -3.89
Rotatable Bond Count 4.0
Logd 0.75
Synonyms (-)-Gallocatechin 3-O-gallate, 3,3',4',5,5',7-Hexahydroxyflavan, (2S,3R)-form, 3-O-(3,4,5-Trihydroxybenzoyl), ent-Gallocatechin 3-gallate, L-Gallocatechin 3-gallate, (-)-Gallocatechin-3-O-gallate, (-)-Gallocatechol gallate, (2S,3R)-2-(3,4,5-Trihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol 3-(3,4,5-trihydroxybenzoate), (2S,3R)-5,7-Dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3-yl 3,4,5-trihydroxybenzoate, (-)-Gallocatechin-3-O-gallic acid, (-)-Gallocatechol gallic acid, (2S,3R)-2-(3,4,5-Trihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol 3-(3,4,5-trihydroxybenzoic acid), (2S,3R)-5,7-Dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3-yl 3,4,5-trihydroxybenzoic acid, (-)-Gallocatechin gallic acid, Gallocatechin gallate, Gallocatechin-3-gallate, ent-Gallocatechin 3-gallic acid, gallocatechin gallate, gallocatechin gallate,(-)-
Esol Class Soluble
Functional Groups cC(=O)OC, cO, cOC
Compound Name (-)-Gallocatechin gallate
Kingdom Organic compounds
Prediction Hob Swissadme 0.0
Exact Mass 458.085
Formal Charge 0.0
Monoisotopic Mass 458.085
Hydrogen Bond Acceptor Count 11.0
Molecular Weight 458.4
Gi Absorption False
Covalent Unit Count 1.0
Total Atom Stereocenter Count 2.0
Total Bond Stereocenter Count 0.0
Molecular Framework Aromatic heteromonocyclic compounds
Lipinski Rule Of 5 False
Esol -3.558661363636364
Inchi InChI=1S/C22H18O11/c23-10-5-12(24)11-7-18(33-22(31)9-3-15(27)20(30)16(28)4-9)21(32-17(11)6-10)8-1-13(25)19(29)14(26)2-8/h1-6,18,21,23-30H,7H2/t18-,21+/m1/s1
Smiles C1[C@H]([C@@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O
Nring 4.0
Np Classifier Biosynthetic Pathway Shikimates and Phenylpropanoids
Defined Bond Stereocenter Count 0.0
Egan Rule False
Taxonomy Direct Parent Flavonoid O-glycosides
Np Classifier Superclass Flavonoids

  • 1. Outgoing r'ship FOUND_IN to/from Camellia Sinensis (Plant) Rel Props:Source_db:cmaup_ingredients;fooddb_chem_all;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Daucus Carota (Plant) Rel Props:Source_db:npass_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Morus Alba (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 4. Outgoing r'ship FOUND_IN to/from Paeonia Lactiflora (Plant) Rel Props:Source_db:npass_chem_all
  • 5. Outgoing r'ship FOUND_IN to/from Solanum Nigrum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all