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4-Desacetylvinblastine

PubChem CID: 197026

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Compound Synonyms 4-Desacetylvinblastine, Desacetylvinblastine, 3352-69-0, 4-Deacetylvinblastine, Deacetylvinblastine, Vincaleukoblastine, deacetyl-, Vincaleukoblastine, O(sup 4)-deacetyl-, 4-Desacetyl Vinblastine, methyl (9R,10S,11R,12R,19R)-12-ethyl-4-[(13S,15S,17S)-17-ethyl-17-hydroxy-13-methoxycarbonyl-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraen-13-yl]-10,11-dihydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraene-10-carboxylate, methyl (3aR,3a1R,4R,5S,5aR)-3a-ethyl-9-((5S,7S,9S)-5-ethyl-5-hydroxy-9-(methoxycarbonyl)-1,4,5,6,7,8,9,10-octahydro-2H-3,7-methano[1]azacycloundecino[5,4-b]indol-9-yl)-4,5-dihydroxy-8-methoxy-6-methyl-3a,3a1,4,5,5a,6,11,12-octahydro-1H-indolizino[8,1-cd]carbazole-5-carboxylate, deacetyl-vinblastine, methyl (9R,10S,11R,12R,19R)-12-ethyl-4-((13S,15S,17S)-17-ethyl-17-hydroxy-13-methoxycarbonyl-1,11-diazatetracyclo(13.3.1.04,12.05,10)nonadeca-4(12),5,7,9-tetraen-13-yl)-10,11-dihydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo(10.6.1.01,9.02,7.016,19)nonadeca-2,4,6,13-tetraene-10-carboxylate, 17-desacetylvinblastine, O(4)-deacetylvinblastine, UNII-2Q5SB43WZ2, DVBL-O(4), CHEBI:172822, NDMPLJNOPCLANR-SAYSVMKTSA-N
Prediction Swissadme 0.0
Topological Polar Surface Area 148.0
Hydrogen Bond Donor Count 4.0
Inchi Key NDMPLJNOPCLANR-SAYSVMKTSA-N
Fcsp3 0.5909090909090909
Rotatable Bond Count 8.0
Heavy Atom Count 56.0
Compound Name 4-Desacetylvinblastine
Prediction Hob Swissadme 0.0
Exact Mass 768.41
Formal Charge 0.0
Monoisotopic Mass 768.41
Isotope Atom Count 0.0
Molecular Complexity 1580.0
Hydrogen Bond Acceptor Count 11.0
Molecular Weight 768.9
Database Name cmaup_ingredients;pubchem
Covalent Unit Count 1.0
Defined Atom Stereocenter Count 8.0
Iupac Name methyl (9R,10S,11R,12R,19R)-12-ethyl-4-[(13S,15S,17S)-17-ethyl-17-hydroxy-13-methoxycarbonyl-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraen-13-yl]-10,11-dihydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraene-10-carboxylate
Total Atom Stereocenter Count 9.0
Total Bond Stereocenter Count 0.0
Prediction Hob 0.0
Esol -6.709516685714288
Inchi InChI=1S/C44H56N4O8/c1-7-40(52)22-26-23-43(38(50)55-5,34-28(14-18-47(24-26)25-40)27-12-9-10-13-31(27)45-34)30-20-29-32(21-33(30)54-4)46(3)36-42(29)16-19-48-17-11-15-41(8-2,35(42)48)37(49)44(36,53)39(51)56-6/h9-13,15,20-21,26,35-37,45,49,52-53H,7-8,14,16-19,22-25H2,1-6H3/t26-,35+,36-,37-,40+,41-,42?,43+,44+/m1/s1
Smiles CC[C@@]1(C[C@@H]2C[C@@](C3=C(CCN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)C78CCN9[C@H]7[C@@](C=CC9)([C@H]([C@@]([C@@H]8N6C)(C(=O)OC)O)O)CC)OC)C(=O)OC)O
Xlogp 3.7
Defined Bond Stereocenter Count 0.0
Molecular Formula C44H56N4O8

  • 1. Outgoing r'ship FOUND_IN to/from Catharanthus Roseus (Plant) Rel Props:Source_db:cmaup_ingredients