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Ancistrocladidine

PubChem CID: 193880

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Compound Synonyms Ancistrocladidine, 52659-52-6, 2-[(3s)-6,8-dimethoxy-1,3-dimethyl-3,4-dihydroisoquinolin-7-yl]-8-methoxy-3-methylnaphthalen-1-ol, 2-((3S)-6,8-dimethoxy-1,3-dimethyl-3,4-dihydroisoquinolin-7-yl)-8-methoxy-3-methylnaphthalen-1-ol, 7,3'-Linked naphthylisoquinoline alkaloid, CHEMBL222436, DTXSID40967087, 7,3'-Linked naphthylisoquinoline alkaloid, 2-(6,8-Dimethoxy-1,3-dimethyl-3,4-dihydroisoquinolin-7-yl)-8-methoxy-3-methylnaphthalen-1-ol
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 60.3
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC2CC(C3CCC4CCCCC4C3)CCC2C1
Np Classifier Class Isoquinoline alkaloids
Deep Smiles COcccC[C@H]C)N=Cc6cc%10ccC)cccc6O))cOC))ccc6))))))))))OC))))C
Heavy Atom Count 30.0
Classyfire Class Isoquinolines and derivatives
Scaffold Graph Node Level C1CCC2CC(C3CCC4CCNCC4C3)CCC2C1
Classyfire Subclass Naphthylisoquinolines
Isotope Atom Count 0.0
Molecular Complexity 624.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 1.0
Iupac Name 2-[(3S)-6,8-dimethoxy-1,3-dimethyl-3,4-dihydroisoquinolin-7-yl]-8-methoxy-3-methylnaphthalen-1-ol
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Organoheterocyclic compounds
Xlogp 4.8
Gsk 4 400 Rule False
Molecular Formula C25H27NO4
Scaffold Graph Node Bond Level C1=NCCc2ccc(-c3ccc4ccccc4c3)cc21
Prediction Swissadme 1.0
Inchi Key CESMSNGGFQBVOV-AWEZNQCLSA-N
Silicos It Class Poorly soluble
Fcsp3 0.32
Logs -6.456
Rotatable Bond Count 4.0
Logd 3.653
Synonyms ancistrocladidine
Esol Class Moderately soluble
Functional Groups cC(C)=NC, cO, cOC
Compound Name Ancistrocladidine
Prediction Hob Swissadme 1.0
Exact Mass 405.194
Formal Charge 0.0
Monoisotopic Mass 405.194
Hydrogen Bond Acceptor Count 5.0
Molecular Weight 405.5
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 1.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -5.533929466666667
Inchi InChI=1S/C25H27NO4/c1-13-10-16-8-7-9-18(28-4)22(16)24(27)20(13)23-19(29-5)12-17-11-14(2)26-15(3)21(17)25(23)30-6/h7-10,12,14,27H,11H2,1-6H3/t14-/m0/s1
Smiles C[C@H]1CC2=CC(=C(C(=C2C(=N1)C)OC)C3=C(C4=C(C=CC=C4OC)C=C3C)O)OC
Nring 4.0
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tyrosine alkaloids