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Palmatine

PubChem CID: 19009

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Compound Synonyms Palmatine, 3486-67-7, Berbericinine, Palmatin, O,O-Dimethyldemethyleneberberine, Dibenzo[a,g]quinolizinium, 5,6-dihydro-2,3,9,10-tetramethoxy-, Burasaine, palmatine ion, palmatine cation, 2,3,9,10-tetramethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium, 7,8,13,13a-Tetrahydro-2,3,9,10-tetramethoxyberbinium, BRN 1555498, CHEBI:16096, UNII-G50C034217, 5,6-Dihydro-2,3,9,10-tetramethoxydibenzo(a,g)quinolizinium, DTXSID9048065, G50C034217, 5,6-Dihydro-2,3,9,10-tetramethoxydibenzo[a,g]quinolizinium, 2,3,9,10-tetramethoxy-5,6-dihydroisoquino[3,2-a]isoquinolinium, Dibenzo(a,g)quinolizinium, 5,6-dihydro-2,3,9,10-tetramethoxy-, 5-21-06-00202 (Beilstein Handbook Reference), GNF-PF-4086, BERBINIUM, 7,8,13,13a-TETRAHYDRO-2,3,9,10-TETRAMETHOXY-, 5,6-Dihydro-2,3,9,10-tetramethoxy-dibenzo[a,g]quinolizinium, 2,3,9,10-tetramethoxy-5,6-dihydroisoquinolino[3,2-a]isoquinolin-7-ium, CHEMBL274189, 2,3,9,10-tetramethoxy-5,6-dihydroisoquino(3,2-a)isoquinolinium, SR-01000841226, C21H22NO4, Palmatine-chloride, PALMITINE, Spectrum_001849, SpecPlus_000619, SpecPlus_000738, PALMATINE [MI], Prestwick0_000579, Prestwick1_000579, Prestwick2_000579, Prestwick3_000579, Spectrum2_000608, Spectrum3_000907, Spectrum4_001005, Spectrum5_000684, Spectrum5_001860, PALMATINE [WHO-DD], BSPBio_000398, BSPBio_002629, KBioGR_001469, KBioSS_002363, DivK1c_006715, DivK1c_006834, SCHEMBL562120, SPBio_000516, SPBio_002617, BPBio1_000438, CHEMBL206106, DTXCID0028036, HY-N0110A, KBio1_001659, KBio1_001778, KBio2_002360, KBio2_004928, KBio2_007496, KBio3_001854, 7,8,13,13a-tetradehydro-2,3,9,10-tetramethoxyberbinium, QUCQEUCGKKTEBI-UHFFFAOYSA-N, HMS3885G04, 2,3,9,10-tetramethoxy-5,6-dihydro-isoquino[3,2-a]isoquinolinylium, BBL028417, BDBM50292332, s3769, STK801361, AKOS005612997, AC-7992, CCG-268056, FP65894, SDCCGMLS-0066652.P001, NCGC00016631-01, NCGC00016631-02, NCGC00016631-03, NCI60_001757, CAS-3486-67-7, DB-048694, CS-0013950, NS00094853, C05315, AE-508/43280806, Q6634283, SR-01000841226-5, BRD-K58466253-003-04-1, BRD-K58466253-003-07-4, BRD-K58466253-003-14-0, PALMATINE (NEGATIVE MARKER) (CONSTITUENT OF GOLDENSEAL), PALMATINE (NEGATIVE MARKER) (CONSTITUENT OF GOLDENSEAL) [DSC], 2,3,9,10-Tetramethoxy-5,6-dihydro-isoquino[3,2-a]isoquinolinylium, chloride
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 40.8
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC2CC3C(CCC4CCCCC43)CC2C1
Np Classifier Class Protoberberine alkaloids, Isoquinoline alkaloids
Deep Smiles COcccCC[n+]c-c6cc%10OC)))))cccc6)cOC))ccc6))OC
Heavy Atom Count 26.0
Classyfire Class Protoberberine alkaloids and derivatives
Scaffold Graph Node Level C1CCC2CN3CCC4CCCCC4C3CC2C1
Isotope Atom Count 0.0
Molecular Complexity 475.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Uniprot Id P02545, Q16665, O97447, P10635, O94782, Q9Y6L6, Q9NPD5, P03469, P06935, P18031, P06276, P22303, P48147, n.a., Q09472
Iupac Name 2,3,9,10-tetramethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Target Id NPT483, NPT211, NPT110, NPT178, NPT204, NPT1079
Xlogp 3.7
Gsk 4 400 Rule True
Molecular Formula C21H22NO4+
Scaffold Graph Node Bond Level c1ccc2c(c1)CC[n+]1cc3ccccc3cc1-2
Prediction Swissadme 1.0
Inchi Key QUCQEUCGKKTEBI-UHFFFAOYSA-N
Silicos It Class Poorly soluble
Fcsp3 0.2857142857142857
Logs -5.366
Rotatable Bond Count 4.0
Logd 3.562
Synonyms berbericinine, gindarinine, palmatine, palmitine
Esol Class Moderately soluble
Functional Groups cOC, c[n+](c)C
Compound Name Palmatine
Prediction Hob Swissadme 1.0
Exact Mass 352.155
Formal Charge 1.0
Monoisotopic Mass 352.155
Hydrogen Bond Acceptor Count 4.0
Molecular Weight 352.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 0.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -4.5788266153846156
Inchi InChI=1S/C21H22NO4/c1-23-18-6-5-13-9-17-15-11-20(25-3)19(24-2)10-14(15)7-8-22(17)12-16(13)21(18)26-4/h5-6,9-12H,7-8H2,1-4H3/q+1
Smiles COC1=C(C2=C[N+]3=C(C=C2C=C1)C4=CC(=C(C=C4CC3)OC)OC)OC
Nring 4.0
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tyrosine alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Achyrocline Satureioides (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Acnistus Arborescens (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Acorus Calamus (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 4. Outgoing r'ship FOUND_IN to/from Aeschynomene Indica (Plant) Rel Props:Source_db:npass_chem_all
  • 5. Outgoing r'ship FOUND_IN to/from Agathosma Bisulca (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 6. Outgoing r'ship FOUND_IN to/from Aloe Saponaria (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 7. Outgoing r'ship FOUND_IN to/from Anamirta Cocculus (Plant) Rel Props:Reference:ISBN:9789327275590
  • 8. Outgoing r'ship FOUND_IN to/from Androsace Septentrionalis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 9. Outgoing r'ship FOUND_IN to/from Annona Glabra (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 10. Outgoing r'ship FOUND_IN to/from Artocarpus Incisa (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 11. Outgoing r'ship FOUND_IN to/from Astragalus Trojanus (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 12. Outgoing r'ship FOUND_IN to/from Berberis Amurensis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 13. Outgoing r'ship FOUND_IN to/from Berberis Aristata (Plant) Rel Props:Reference:ISBN:9788171360536; ISBN:9788172363130; Standardization of Single Drugs of Unani Medicine Part - III
  • 14. Outgoing r'ship FOUND_IN to/from Berberis Asiatica (Plant) Rel Props:Reference:ISBN:9770972795006
  • 15. Outgoing r'ship FOUND_IN to/from Berberis Brandisiana (Plant) Rel Props:Reference:ISBN:9788185042138
  • 16. Outgoing r'ship FOUND_IN to/from Berberis Chitria (Plant) Rel Props:Reference:ISBN:9770972795006; ISBN:9788185042138
  • 17. Outgoing r'ship FOUND_IN to/from Berberis Concinna (Plant) Rel Props:Reference:ISBN:9788185042084
  • 18. Outgoing r'ship FOUND_IN to/from Berberis Diaphana (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 19. Outgoing r'ship FOUND_IN to/from Berberis Dubia (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 20. Outgoing r'ship FOUND_IN to/from Berberis Floribunda (Plant) Rel Props:Reference:ISBN:9770972795006
  • 21. Outgoing r'ship FOUND_IN to/from Berberis Fortunei (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 22. Outgoing r'ship FOUND_IN to/from Berberis Japonica (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 23. Outgoing r'ship FOUND_IN to/from Berberis Lambertii (Plant) Rel Props:Reference:ISBN:9770972795006
  • 24. Outgoing r'ship FOUND_IN to/from Berberis Lycium (Plant) Rel Props:Reference:ISBN:9770972795006
  • 25. Outgoing r'ship FOUND_IN to/from Berberis Oblonga (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 26. Outgoing r'ship FOUND_IN to/from Berberis Petiolaris (Plant) Rel Props:Reference:ISBN:9788172360481; ISBN:9788185042084
  • 27. Outgoing r'ship FOUND_IN to/from Berberis Poiretii (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 28. Outgoing r'ship FOUND_IN to/from Berberis Potaninii (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 29. Outgoing r'ship FOUND_IN to/from Berberis Pseudumbellata (Plant) Rel Props:Reference:ISBN:9788185042138
  • 30. Outgoing r'ship FOUND_IN to/from Berberis Thunbergii (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 31. Outgoing r'ship FOUND_IN to/from Berberis Tinctoria (Plant) Rel Props:Reference:ISBN:9770972795006
  • 32. Outgoing r'ship FOUND_IN to/from Berberis Vulgaris (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 33. Outgoing r'ship FOUND_IN to/from Brickellia Dentata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 34. Outgoing r'ship FOUND_IN to/from Calocephalus Knappii (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 35. Outgoing r'ship FOUND_IN to/from Calystegia Hederacea (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 36. Outgoing r'ship FOUND_IN to/from Chrysanthemum Myconis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 37. Outgoing r'ship FOUND_IN to/from Cocculus Pendulus (Plant) Rel Props:Reference:ISBN:9788172361266
  • 38. Outgoing r'ship FOUND_IN to/from Coptis Chinensis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 39. Outgoing r'ship FOUND_IN to/from Coptis Deltoidea (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 40. Outgoing r'ship FOUND_IN to/from Coptis Gulinensis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 41. Outgoing r'ship FOUND_IN to/from Coptis Japonica (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 42. Outgoing r'ship FOUND_IN to/from Coptis Linearisepala (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 43. Outgoing r'ship FOUND_IN to/from Coptis Omeiensis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 44. Outgoing r'ship FOUND_IN to/from Coptis Teeta (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 45. Outgoing r'ship FOUND_IN to/from Coptis Teetoides (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 46. Outgoing r'ship FOUND_IN to/from Corydalis Adunca (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 47. Outgoing r'ship FOUND_IN to/from Corydalis Ambigua (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 48. Outgoing r'ship FOUND_IN to/from Corydalis Decumbens (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 49. Outgoing r'ship FOUND_IN to/from Corydalis Ledebouriana (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 50. Outgoing r'ship FOUND_IN to/from Corydalis Longicalcarata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 51. Outgoing r'ship FOUND_IN to/from Corydalis Remota (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 52. Outgoing r'ship FOUND_IN to/from Corydalis Repens (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 53. Outgoing r'ship FOUND_IN to/from Corydalis Ternata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 54. Outgoing r'ship FOUND_IN to/from Corydalis Turtschaninovii (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 55. Outgoing r'ship FOUND_IN to/from Corydalis Yanhusuo (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 56. Outgoing r'ship FOUND_IN to/from Coscinium Fenestratum (Plant) Rel Props:Reference:ISBN:9788185042114
  • 57. Outgoing r'ship FOUND_IN to/from Cussonia Racemosa (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 58. Outgoing r'ship FOUND_IN to/from Dunaliella Salina (Plant) Rel Props:Source_db:npass_chem_all
  • 59. Outgoing r'ship FOUND_IN to/from Epimedium Koreanum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 60. Outgoing r'ship FOUND_IN to/from Euphorbia Fortissima (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 61. Outgoing r'ship FOUND_IN to/from Fibraurea Recisa (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 62. Outgoing r'ship FOUND_IN to/from Fibraurea Tinctoria (Plant) Rel Props:Reference:ISBN:9788185042053
  • 63. Outgoing r'ship FOUND_IN to/from Garcinia Paucinervis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 64. Outgoing r'ship FOUND_IN to/from Gaultheria Yunnanensis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 65. Outgoing r'ship FOUND_IN to/from Horsfieldia Iryaghedhi (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 66. Outgoing r'ship FOUND_IN to/from Hylomecon Japonica (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 67. Outgoing r'ship FOUND_IN to/from Hymenoxys Ivesiana (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 68. Outgoing r'ship FOUND_IN to/from Isodon Wikstroemioides (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 69. Outgoing r'ship FOUND_IN to/from Jateorhiza Palmata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 70. Outgoing r'ship FOUND_IN to/from Karwinskia Subcordata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 71. Outgoing r'ship FOUND_IN to/from Lamprocapnos Spectabilis (Plant) Rel Props:Reference:ISBN:9788185042145
  • 72. Outgoing r'ship FOUND_IN to/from Ligularia Nelumbifolia (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 73. Outgoing r'ship FOUND_IN to/from Macaranga Bicolor (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 74. Outgoing r'ship FOUND_IN to/from Magnolia Biondii (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 75. Outgoing r'ship FOUND_IN to/from Maytenus Octogona (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 76. Outgoing r'ship FOUND_IN to/from Medicago Hispida (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 77. Outgoing r'ship FOUND_IN to/from Panax Quinquefolius (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 78. Outgoing r'ship FOUND_IN to/from Papaver Orientale (Plant) Rel Props:Reference:ISBN:9788185042145
  • 79. Outgoing r'ship FOUND_IN to/from Papaver Somniferum (Plant) Rel Props:Reference:ISBN:9788185042145
  • 80. Outgoing r'ship FOUND_IN to/from Paratinospora Sagittata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 81. Outgoing r'ship FOUND_IN to/from Passiflora Coccinea (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 82. Outgoing r'ship FOUND_IN to/from Phellodendron Amurense (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 83. Outgoing r'ship FOUND_IN to/from Phellodendron Chinense (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 84. Outgoing r'ship FOUND_IN to/from Phellodendron Chinese (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 85. Outgoing r'ship FOUND_IN to/from Pilosocereus Chrysacanthus (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 86. Outgoing r'ship FOUND_IN to/from Pinus Koraiensis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 87. Outgoing r'ship FOUND_IN to/from Plectranthus Ernstii (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 88. Outgoing r'ship FOUND_IN to/from Stephania Glabra (Plant) Rel Props:Source_db:npass_chem_all
  • 89. Outgoing r'ship FOUND_IN to/from Stephania Tetrandra (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 90. Outgoing r'ship FOUND_IN to/from Stephania Viridiflavens (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 91. Outgoing r'ship FOUND_IN to/from Tephrosia Falciformis (Plant) Rel Props:Source_db:npass_chem_all
  • 92. Outgoing r'ship FOUND_IN to/from Thalictrum Alpinum (Plant) Rel Props:Reference:ISBN:9788185042114
  • 93. Outgoing r'ship FOUND_IN to/from Thalictrum Atriplex (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 94. Outgoing r'ship FOUND_IN to/from Thalictrum Faberi (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 95. Outgoing r'ship FOUND_IN to/from Thalictrum Foliolosum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 96. Outgoing r'ship FOUND_IN to/from Thalictrum Glandulosissimum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 97. Outgoing r'ship FOUND_IN to/from Thalictrum Javanicum (Plant) Rel Props:Reference:ISBN:9788185042114
  • 98. Outgoing r'ship FOUND_IN to/from Thalictrum Microgynum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 99. Outgoing r'ship FOUND_IN to/from Thalictrum Minus (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 100. Outgoing r'ship FOUND_IN to/from Thalictrum Petaloideum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 101. Outgoing r'ship FOUND_IN to/from Thalictrum Simplex (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 102. Outgoing r'ship FOUND_IN to/from Theobroma Speciosum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 103. Outgoing r'ship FOUND_IN to/from Tinospora Capillipes (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 104. Outgoing r'ship FOUND_IN to/from Tinospora Craveniana (Plant) Rel Props:Source_db:npass_chem_all
  • 105. Outgoing r'ship FOUND_IN to/from Tinospora Sinensis (Plant) Rel Props:Reference:ISBN:9788185042145
  • 106. Outgoing r'ship FOUND_IN to/from Trifolium Dubium (Plant) Rel Props:Source_db:npass_chem_all