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Egenine

PubChem CID: 189685

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Compound Synonyms Egenine, Decumbensine, (+)-Egenine, 6883-44-9, (+)-Decumbensine, (6R,8S)-6-((S)-6-Methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-6,8-dihydro-[1,3]dioxolo[4,5-e]isobenzofuran-8-ol, Furo(3,4-e)-1,3-benzodioxol-8-ol, 6,8-dihydro-6-(5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo(4,5-g)isoquinolin-5-yl)-, (6R-(6alpha(S*),8alpha))-, 119736-64-0, (6R,8S)-6-[(5S)-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-6,8-dihydrofuro[3,4-g][1,3]benzodioxol-8-ol, SCHEMBL12904807, DTXSID30923096, 6-(6-Methyl-5,6,7,8-tetrahydro-2H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-6,8-dihydro-2H-furo[3,4-e][1,3]benzodioxol-8-ol
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 69.6
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CC2CC3CCCC(C4CCC5C6CCCC6CCC54)C3CC2C1
Np Classifier Class Isoquinoline alkaloids, Phthalide derivatives, Tetrahydroisoquinoline alkaloids
Deep Smiles CNCCcc[C@H]6[C@@H]O[C@@H]cc5cccc6OCO5)))))))))O)))))cccc6)OCO5
Heavy Atom Count 27.0
Classyfire Class Tetrahydroisoquinolines
Scaffold Graph Node Level C1CC2CC3OCOC3CC2C(C2OCC3C2CCC2OCOC23)N1
Isotope Atom Count 0.0
Molecular Complexity 577.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 3.0
Iupac Name (6R,8S)-6-[(5S)-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-6,8-dihydrofuro[3,4-g][1,3]benzodioxol-8-ol
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Organoheterocyclic compounds
Xlogp 1.9
Gsk 4 400 Rule True
Molecular Formula C20H19NO6
Scaffold Graph Node Bond Level c1c2c(cc3c1OCO3)C(C1OCc3c1ccc1c3OCO1)NCC2
Prediction Swissadme 1.0
Inchi Key YMHFBUOKLSWOQF-NSHGMRRFSA-N
Silicos It Class Soluble
Fcsp3 0.4
Logs -1.327
Rotatable Bond Count 1.0
Logd 1.045
Synonyms egenine, egenine,(+)-
Esol Class Soluble
Functional Groups CN(C)C, c1cOCO1, c[C@@H](O)OC
Compound Name Egenine
Prediction Hob Swissadme 1.0
Exact Mass 369.121
Formal Charge 0.0
Monoisotopic Mass 369.121
Hydrogen Bond Acceptor Count 7.0
Molecular Weight 369.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 3.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -3.55850148888889
Inchi InChI=1S/C20H19NO6/c1-21-5-4-10-6-14-15(25-8-24-14)7-12(10)17(21)18-11-2-3-13-19(26-9-23-13)16(11)20(22)27-18/h2-3,6-7,17-18,20,22H,4-5,8-9H2,1H3/t17-,18+,20-/m0/s1
Smiles CN1CCC2=CC3=C(C=C2[C@H]1[C@H]4C5=C([C@H](O4)O)C6=C(C=C5)OCO6)OCO3
Nring 1.0
Np Classifier Biosynthetic Pathway Alkaloids, Polyketides
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tyrosine alkaloids, Cyclic polyketides

  • 1. Outgoing r'ship FOUND_IN to/from Corydalis Decumbens (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Fumaria Vaillantii (Plant) Rel Props:Reference:ISBN:9788185042145