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Columbin

PubChem CID: 188289

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Compound Synonyms Columbin, 546-97-4, UNII-KKI91P85GE, KKI91P85GE, (1S,2S,3S,5S,8R,11R,12S)-5-(Furan-3-yl)-12-hydroxy-3,11-dimethyl-6,14-dioxatetracyclo[10.2.2.02,11.03,8]hexadec-15-ene-7,13-dione, COLUMBIN [MI], 4-Hydroxy-15,16-epoxycleroda-2,13(16),14-trieno-17,12-18,1-biscarbolactone, s9167, AKOS037514594, CCG-268135, FC66014, 1,4-Etheno-3H,7H-benzo(1,2-c:3,4-c')dipyran-3,7-dione, 9-(3-furanyl)-1,4,4a,5,6,6a,9,10,10a,10b-decahydro-4-hydroxy-4a,10a-dimethyl-, (1R-(1alpha,4beta,4aalpha,6abeta,9beta,10abeta,10balpha))-, (1R,4R,4AR,6AR,9S,10AS,10BS)-9-(3-FURANYL)-1,4,4A,5,6,6A,9,10,10A,10B-DECAHYDRO-4-HYDROXY-4A,10A-DIMETHYL-1,4-ETHENO-3H,7H-BENZO(1,2-C:3,4-C')DIPYRAN-3,7-DIONE
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 86.0
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule True
Scaffold Graph Level CC1CC2CCC1C1CCC3C(C)CC(C4CCCC4)CC3C21
Np Classifier Class Colensane and Clerodane diterpenoids
Deep Smiles O=CO[C@@H]C[C@@][C@H]6CC[C@@][C@H]6[C@@H]C=C[C@@]6O)C=O)O6)))))))C)))))C)))ccocc5
Heavy Atom Count 26.0
Classyfire Class Naphthopyrans
Scaffold Graph Node Level OC1OC(C2CCOC2)CC2C1CCC1C3CCC(OC3O)C21
Isotope Atom Count 0.0
Molecular Complexity 702.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 7.0
Iupac Name (1S,2S,3S,5S,8R,11R,12S)-5-(furan-3-yl)-12-hydroxy-3,11-dimethyl-6,14-dioxatetracyclo[10.2.2.02,11.03,8]hexadec-15-ene-7,13-dione
Veber Rule True
Classyfire Superclass Organoheterocyclic compounds
Xlogp 2.2
Gsk 4 400 Rule True
Molecular Formula C20H22O6
Scaffold Graph Node Bond Level O=C1OC2C=CC1C1CCC3C(=O)OC(c4ccoc4)CC3C21
Inchi Key AALLCALQGXXWNA-DURQJQQASA-N
Silicos It Class Soluble
Rotatable Bond Count 1.0
Synonyms columbin, columbin[(1s,2s,3r,4r,5r,8s,10r,12s)-4-hydroxy-15,16-epoxycleroda-2,12(16),14-trieno-17,12,18,1-biscarbolactone]
Esol Class Soluble
Functional Groups CC=CC, CO, COC(C)=O, coc
Compound Name Columbin
Exact Mass 358.142
Formal Charge 0.0
Monoisotopic Mass 358.142
Hydrogen Bond Acceptor Count 6.0
Molecular Weight 358.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 7.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C20H22O6/c1-18-9-14(11-5-8-24-10-11)25-16(21)12(18)3-6-19(2)15(18)13-4-7-20(19,23)17(22)26-13/h4-5,7-8,10,12-15,23H,3,6,9H2,1-2H3/t12-,13-,14-,15-,18+,19+,20+/m0/s1
Smiles C[C@@]12CC[C@H]3C(=O)O[C@@H](C[C@]3([C@@H]1[C@@H]4C=C[C@]2(C(=O)O4)O)C)C5=COC=C5
Np Classifier Biosynthetic Pathway Terpenoids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Diterpenoids

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