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O-methylthalibrine

PubChem CID: 185953

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Compound Synonyms O-methylthalibrine, 59654-05-6, CHEMBL447344, DTXSID30975055, CHEBI:188627, (1S)-1-[[4-[5-[[(1S)-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-1-yl]methyl]-2-methoxyphenoxy]phenyl]methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinoline, 1-[(4-{5-[(6,7-Dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-1-yl)methyl]-2-methoxyphenoxy}phenyl)methyl]-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline
Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 61.9
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CC(CC2CCC(CC3CCCC4CCCCC43)CC2)CC(CC2CCCC3CCCCC32)C1
Np Classifier Class Isoquinoline alkaloids, Tetrahydroisoquinoline alkaloids
Deep Smiles COcccccc6Occcccc6))C[C@@H]NC)CCcc6ccOC))cc6)OC)))))))))))))))))))C[C@@H]NC)CCcc6ccOC))cc6)OC
Heavy Atom Count 47.0
Classyfire Class Isoquinolines and derivatives
Scaffold Graph Node Level C1CC(CC2NCCC3CCCCC32)CC(OC2CCC(CC3NCCC4CCCCC43)CC2)C1
Classyfire Subclass Benzylisoquinolines
Isotope Atom Count 0.0
Molecular Complexity 948.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 2.0
Iupac Name (1S)-1-[[4-[5-[[(1S)-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-1-yl]methyl]-2-methoxyphenoxy]phenyl]methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinoline
Veber Rule False
Classyfire Superclass Organoheterocyclic compounds
Xlogp 7.0
Gsk 4 400 Rule False
Molecular Formula C39H46N2O6
Scaffold Graph Node Bond Level c1cc(CC2NCCc3ccccc32)cc(Oc2ccc(CC3NCCc4ccccc43)cc2)c1
Inchi Key UHYCXSGUNAWVBW-LQJZCPKCSA-N
Silicos It Class Insoluble
Rotatable Bond Count 11.0
Synonyms o-methylthalibrine
Esol Class Poorly soluble
Functional Groups CN(C)C, cOC, cOc
Compound Name O-methylthalibrine
Exact Mass 638.336
Formal Charge 0.0
Monoisotopic Mass 638.336
Hydrogen Bond Acceptor Count 8.0
Molecular Weight 638.8
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 2.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 False
Inchi InChI=1S/C39H46N2O6/c1-40-16-14-27-21-35(43-4)37(45-6)23-30(27)32(40)18-25-8-11-29(12-9-25)47-39-20-26(10-13-34(39)42-3)19-33-31-24-38(46-7)36(44-5)22-28(31)15-17-41(33)2/h8-13,20-24,32-33H,14-19H2,1-7H3/t32-,33-/m0/s1
Smiles CN1CCC2=CC(=C(C=C2[C@@H]1CC3=CC=C(C=C3)OC4=C(C=CC(=C4)C[C@H]5C6=CC(=C(C=C6CCN5C)OC)OC)OC)OC)OC
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule False
Np Classifier Superclass Tyrosine alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Thalictrum Minus (Plant) Rel Props:Reference:ISBN:9788185042114