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Rescinnamidine

PubChem CID: 184180

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Compound Synonyms Rescinnamidine, 110222-52-1, Methyl (1R,15S,17R,18R,19S,20S)-6,18-dimethoxy-17-[3-(3,4,5-trimethoxyphenyl)propanoyloxy]-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate, Reserpic acid, methyl ester, 3,4,5-trimethoxyhydrocinnamate, Benz(g)indolo(2,3-a)quinolizine, yohimban-16-carboxylic acid deriv, Yohimban-16-carboxylic acid, 11,17-dimethoxy-18-(1-oxo-3-(3,4,5-trimethoxyphenyl)propoxy)-, methyl ester, (3beta,16beta,17alpha,18beta,20alpha), methyl (1R,15S,17R,18R,19S,20S)-6,18-dimethoxy-17-(3-(3,4,5-trimethoxyphenyl)propanoyloxy)-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate, 2',3'-Dihydrorescinnamine, DTXSID40911545, AKOS040753729, methyl (1S,2R,3R,4aS,13bR,14aS)-2,11-dimethoxy-3-((3-(3,4,5-trimethoxyphenyl)propanoyl)oxy)-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroindolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylate, methyl (3beta,16beta,17alpha,18beta,20alpha)-11,17-dimethoxy-18-{[3-(3,4,5-trimethoxyphenyl)propanoyl]oxy}yohimban-16-carboxylate, methyl 11,17-dimethoxy-18-{[3-(3,4,5-trimethoxyphenyl)propanoyl]oxy}yohimban-16-carboxylate
Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 118.0
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC(CCC1CCCCC1)CC1CCC2CC3C(CCC4C5CCCCC5CC34)CC2C1
Np Classifier Class Yohimbine-like alkaloids
Deep Smiles COcccccc6)[nH]cc5CCN[C@@H]6C[C@H][C@@H]C6)C[C@H][C@@H][C@H]6C=O)OC))))OC)))OC=O)CCcccOC))ccc6)OC)))OC
Heavy Atom Count 46.0
Classyfire Class Yohimbine alkaloids
Scaffold Graph Node Level OC(CCC1CCCCC1)OC1CCC2CC3C4NC5CCCCC5C4CCN3CC2C1
Isotope Atom Count 0.0
Molecular Complexity 1030.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 6.0
Iupac Name methyl (1R,15S,17R,18R,19S,20S)-6,18-dimethoxy-17-[3-(3,4,5-trimethoxyphenyl)propanoyloxy]-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate
Prediction Hob 1.0
Veber Rule False
Classyfire Superclass Alkaloids and derivatives
Xlogp 4.3
Gsk 4 400 Rule False
Molecular Formula C35H44N2O9
Scaffold Graph Node Bond Level O=C(CCc1ccccc1)OC1CCC2CC3c4[nH]c5ccccc5c4CCN3CC2C1
Prediction Swissadme 0.0
Inchi Key PYYLUPQQQNZLDO-LAFLMMDJSA-N
Silicos It Class Poorly soluble
Fcsp3 0.5428571428571428
Logs -4.444
Rotatable Bond Count 12.0
Logd 3.81
Synonyms rescinnamidine
Esol Class Moderately soluble
Functional Groups CC(=O)OC, CN(C)C, COC, COC(C)=O, cOC, c[nH]c
Compound Name Rescinnamidine
Prediction Hob Swissadme 0.0
Exact Mass 636.305
Formal Charge 0.0
Monoisotopic Mass 636.305
Hydrogen Bond Acceptor Count 10.0
Molecular Weight 636.7
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 6.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -5.927204747826088
Inchi InChI=1S/C35H44N2O9/c1-40-21-8-9-22-23-11-12-37-18-20-15-29(46-30(38)10-7-19-13-27(41-2)33(43-4)28(14-19)42-3)34(44-5)31(35(39)45-6)24(20)17-26(37)32(23)36-25(22)16-21/h8-9,13-14,16,20,24,26,29,31,34,36H,7,10-12,15,17-18H2,1-6H3/t20-,24+,26-,29-,31+,34+/m1/s1
Smiles CO[C@H]1[C@@H](C[C@@H]2CN3CCC4=C([C@H]3C[C@@H]2[C@@H]1C(=O)OC)NC5=C4C=CC(=C5)OC)OC(=O)CCC6=CC(=C(C(=C6)OC)OC)OC
Nring 6.0
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids