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Colchiceinamid

PubChem CID: 18397

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Compound Synonyms Colchiceinamid, Colchiceinamide, Colchicine amide, Colchicamide, Colchicenamide, Colchicamid, 3123-89-5, Colchicide, 14-amino-, SKF 3192, COLCHICINE, 10-AMINO-10-DEMETHOXY-, N-[(7S)-10-amino-1,2,3-trimethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide, NSC403144, Acetamide,N-[(7S)-10-amino-5,6,7,9-tetrahydro-1,2,3-trimethoxy-9-oxobenzo[a]heptalen-7-yl]-, 14-Aminocolchicide, Colchicamide (VAN), Colchiceeinamide, Colchiceeinamide [German], N-[(7S)-10-amino-1,2,3-trimethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]acetamide, NSC 403144, BRN 2824077, MFCD25368469, 4-14-00-00921 (Beilstein Handbook Reference), Acetamide, N-(10-amino-5,6,7,9-tetrahydro-1,2,3-trimethoxy-9-oxobenzo(a)heptalen-7-yl)-, (S)-, Colchicamide (colchiceinamide), CHEMBL357889, SCHEMBL12118701, DTXSID00185149, STL530408, AKOS030489333, NSC-403144, Acetamide,6,7,9-tetrahydro-1,2,3-trimethoxy-9-oxobenzo[a]heptalen-7-yl)-, (S)-
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 99.9
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule True
Scaffold Graph Level CC1CCCC2C(CCCC3CCCCC32)C1
Np Classifier Class Phenethylisoquinoline alkaloids
Deep Smiles COccOC))ccc-ccccc=O)cc7[C@H]CC%12))NC=O)C)))))))N)))))c6OC
Heavy Atom Count 28.0
Classyfire Class Tropones
Scaffold Graph Node Level OC1CCCC2C(CCCC3CCCCC32)C1
Isotope Atom Count 0.0
Molecular Complexity 726.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 1.0
Iupac Name N-[(7S)-10-amino-1,2,3-trimethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide
Veber Rule True
Classyfire Superclass Hydrocarbon derivatives
Xlogp 0.3
Gsk 4 400 Rule True
Molecular Formula C21H24N2O5
Scaffold Graph Node Bond Level O=c1cccc2c(c1)CCCc1ccccc1-2
Inchi Key JWDFWIZNGSOUGC-INIZCTEOSA-N
Silicos It Class Poorly soluble
Rotatable Bond Count 4.0
Synonyms colchicamide
Esol Class Soluble
Functional Groups CC(=O)NC, c=O, cN, cOC
Compound Name Colchiceinamid
Exact Mass 384.169
Formal Charge 0.0
Monoisotopic Mass 384.169
Hydrogen Bond Acceptor Count 6.0
Molecular Weight 384.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 1.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C21H24N2O5/c1-11(24)23-16-8-5-12-9-18(26-2)20(27-3)21(28-4)19(12)13-6-7-15(22)17(25)10-14(13)16/h6-7,9-10,16H,5,8H2,1-4H3,(H2,22,25)(H,23,24)/t16-/m0/s1
Smiles CC(=O)N[C@H]1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)N)OC)OC)OC
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tyrosine alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Gloriosa Superba (Plant) Rel Props:Reference:ISBN:9788172362140