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3'-Demethylnobiletin

PubChem CID: 183466

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Compound Synonyms 3'-Demethylnobiletin, 112448-39-2, 3'-hydroxy-5,6,7,8,4'-pentamethoxyflavone, 2-(3-hydroxy-4-methoxyphenyl)-5,6,7,8-tetramethoxychromen-4-one, 96E9T839AP, 3'-Hydroxy-4',5,6,7,8-pentamethoxyflavone, 4H-1-Benzopyran-4-one, 2-(3-hydroxy-4-methoxyphenyl)-5,6,7,8-tetramethoxy-, 2-(3-HYDROXY-4-METHOXYPHENYL)-5,6,7,8-TETRAMETHOXY-4H-1-BENZOPYRAN-4-ONE, UNII-96E9T839AP, CHEMBL225704, SCHEMBL1764091, DTXSID80150057, CHEBI:175928, HY-N4127, MEA44839, LMPK12111478, AKOS030530144, FS-8083, DA-49577, PD125556, CS-0032152, F21505
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 92.7
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1CC(C2CCCCC2)CC2CCCCC12
Np Classifier Class Flavones
Deep Smiles COcccccc6O)))ccc=O)cco6)cOC))ccc6OC)))OC)))OC
Heavy Atom Count 28.0
Classyfire Class Flavonoids
Description Constituent of mandarin orange (Citrus reticulata). 3'-Hydroxy-4',5,6,7,8-pentamethoxyflavone is found in citrus.
Scaffold Graph Node Level OC1CC(C2CCCCC2)OC2CCCCC12
Classyfire Subclass O-methylated flavonoids
Isotope Atom Count 0.0
Molecular Complexity 579.0
Database Name cmaup_ingredients;fooddb_chem_all;hmdb_chem_all;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Iupac Name 2-(3-hydroxy-4-methoxyphenyl)-5,6,7,8-tetramethoxychromen-4-one
Prediction Hob 1.0
Class Flavonoids
Veber Rule True
Classyfire Superclass Phenylpropanoids and polyketides
Xlogp 2.7
Superclass Phenylpropanoids and polyketides
Subclass O-methylated flavonoids
Gsk 4 400 Rule True
Molecular Formula C20H20O8
Scaffold Graph Node Bond Level O=c1cc(-c2ccccc2)oc2ccccc12
Prediction Swissadme 0.0
Inchi Key XFYYZBJXMSDKCV-UHFFFAOYSA-N
Silicos It Class Poorly soluble
Fcsp3 0.25
Logs -4.122
Rotatable Bond Count 6.0
State Solid
Logd 2.642
Synonyms 3'-Hydroxy-4',5,6,7,8-pentamethoxyflavone, 3'-Hydroxy-5,6,7,8,4'-pentamethoxyflavone, 3'-Demethylnobiletin, 3'-dimethyl-nobiletin
Substituent Name 8-methoxyflavonoid-skeleton, 7-methoxyflavonoid-skeleton, 6-methoxyflavonoid-skeleton, 5-methoxyflavonoid-skeleton, 4p-methoxyflavonoid-skeleton, Monohydroxyflavonoid, Flavone, 3'-hydroxyflavonoid, Chromone, 1-benzopyran, Methoxyphenol, Benzopyran, Hydroxyquinol derivative, Methoxybenzene, Phenol ether, Anisole, Pyranone, Phenol, Alkyl aryl ether, Benzenoid, Pyran, Monocyclic benzene moiety, Heteroaromatic compound, Vinylogous ester, Oxacycle, Organoheterocyclic compound, Ether, Hydrocarbon derivative, Organooxygen compound, Aromatic heteropolycyclic compound
Esol Class Soluble
Functional Groups c=O, cO, cOC, coc
Compound Name 3'-Demethylnobiletin
Kingdom Organic compounds
Prediction Hob Swissadme 0.0
Exact Mass 388.116
Formal Charge 0.0
Monoisotopic Mass 388.116
Hydrogen Bond Acceptor Count 8.0
Molecular Weight 388.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 0.0
Total Bond Stereocenter Count 0.0
Molecular Framework Aromatic heteropolycyclic compounds
Lipinski Rule Of 5 True
Esol -3.465463542857144
Inchi InChI=1S/C20H20O8/c1-23-13-7-6-10(8-11(13)21)14-9-12(22)15-16(24-2)18(25-3)20(27-5)19(26-4)17(15)28-14/h6-9,21H,1-5H3
Smiles COC1=C(C=C(C=C1)C2=CC(=O)C3=C(O2)C(=C(C(=C3OC)OC)OC)OC)O
Nring 3.0
Np Classifier Biosynthetic Pathway Shikimates and Phenylpropanoids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Taxonomy Direct Parent 8-O-methylated flavonoids
Np Classifier Superclass Flavonoids