N2-gamma-L-Glutamyl-L-arginine
PubChem CID: 18324563
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| Compound Synonyms | N2-gamma-L-Glutamyl-L-arginine |
|---|---|
| Topological Polar Surface Area | 194.0 |
| Hydrogen Bond Donor Count | 6.0 |
| Inchi Key | AKAHWGGIUSJNNM-UHFFFAOYSA-N |
| Rotatable Bond Count | 10.0 |
| Synonyms | (dimethyltriazeno)imidazolecarboxamide, 1H-Imidazole-4-carboxamide, 5-(3,3-dimethyl-1-triazenyl)-, 4-(3,3-Dimethyl-1-triazeno)imidazole-5-carboxamide, 4-(5)-(3,3-Dimethyl-1-triazeno)imidazole-5(4)-carboxamide, 4-(Dimethyltriazeno)imidazole-5-carboxamide, 4(5)-(3,3-Dimethyl-1-triazeno)imidazole-5(4)-carboxamide, 5-(3,3-Dimethyl-1-triazeno)imidazole-4-carboxamide, 5-(3,3-Dimethyltriazeno)imidazole-4-carboxamide, 5-(Dimethyltriazeno)imidazole-4-carboxamide, 5-(Dimethyltriazeno)imidazole-4-carboximide, Biocarbazine, Biocarbazine r, Carboxamide, 5-(3,3-dimethyl-1-triazeno)imidazole-4-, Carboxamide, dimethyl imidazole, Dacarbazine, Decarbazine, Deticene, Di-me-triazenoimidazolecarboxamide, DIC, Dimethyl imidazole carboxamide, Dimethyl triazeno imidazole carboxamide, Dimethyltriazenoimidazolecarboxamide, DTIC, Dtic dome, Dtic-dome, Dticdome, DTIE, Icdmt, ICDT, Imidazole carboxamide, Imidazole carboxamide, dimethyl, Imidazole-4-carboxamide, 5-(3,3-dimethyl-1-triazeno)- |
| Heavy Atom Count | 21.0 |
| Compound Name | N2-gamma-L-Glutamyl-L-arginine |
| Description | Constituent of Allium cepa (onion), Panax ginseng (ginseng) After intravenous administration of DTIC-Dome, the volume of distribution exceeds total body water content suggesting localization in some body tissue, probably the liver. Its disappearance from the plasma is biphasic with initial half-life of 19 minutes and a terminal half-life of 5 hours. 1 In a patient with renal and hepatic dysfunctions, the half-lives were lengthened to 55 minutes and 7.2 hours. 1 The average cumulative excretion of unchanged DTIC in the urine is 40% of the injected dose in 6 hours. 1 DTIC is subject to renal tubular secretion rather than glomerular filtration. At therapeutic concentrations DTIC is not appreciably bound to human plasma protein. N2-gamma-L-Glutamyl-L-arginine is found in garden onion, tea, and onion-family vegetables. |
| Exact Mass | 303.154 |
| Formal Charge | 0.0 |
| Brenk Violation | True |
| Monoisotopic Mass | 303.154 |
| Isotope Atom Count | 0.0 |
| Molecular Complexity | 408.0 |
| Hydrogen Bond Acceptor Count | 7.0 |
| Molecular Weight | 303.32 |
| Database Name | fooddb_chem_all;pubchem |
| Covalent Unit Count | 1.0 |
| Defined Atom Stereocenter Count | 0.0 |
| Iupac Name | 2-amino-5-[[1-carboxy-4-(diaminomethylideneamino)butyl]amino]-5-oxopentanoic acid |
| Total Atom Stereocenter Count | 2.0 |
| Nih Violation | False |
| Total Bond Stereocenter Count | 0.0 |
| Inchi | InChI=1S/C11H21N5O5/c12-6(9(18)19)3-4-8(17)16-7(10(20)21)2-1-5-15-11(13)14/h6-7H,1-5,12H2,(H,16,17)(H,18,19)(H,20,21)(H4,13,14,15) |
| Smiles | C(CC(C(=O)O)NC(=O)CCC(C(=O)O)N)CN=C(N)N |
| Xlogp | -5.0 |
| Is Pains | False |
| Defined Bond Stereocenter Count | 0.0 |
| Molecular Formula | C11H21N5O5 |
- 1. Outgoing r'ship
FOUND_INto/from Allium Cepa (Plant) Rel Props:Source_db:fooddb_chem_all