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Hypophyllanthin

PubChem CID: 182140

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Compound Synonyms Hypophyllanthin, 33676-00-5, 22ZZ21E33P, (7R,8R,9S)-9-(3,4-dimethoxyphenyl)-4-methoxy-7,8-bis(methoxymethyl)-6,7,8,9-tetrahydrobenzo[g][1,3]benzodioxole, NSC 619044, CHEMBL510130, NSC-619044, (7R,9S)-9-(3,4-dimethoxyphenyl)-4-methoxy-7,8-bis(methoxymethyl)-6,7,8,9-tetrahydrobenzo[g][1,3]benzodioxole, NAPHTHO(1,2-D)-1,3-DIOXOLE, 9-(3,4-DIMETHOXYPHENYL)-6,7,8,9-TETRAHYDRO-4-METHOXY-7,8-BIS(METHOXYMETHYL)-, (7R,8R,9S)-REL-, UNII-22ZZ21E33P, DTXSID50187355, LBJCUHLNHSKZBW-XGHQBKJUSA-N, (7R,8R,9S)-9-(3,4-dimethoxyphenyl)-4-methoxy-7,8-bis(methoxymethyl)-6,7,8,9-tetrahydronaphtho(1,2-d)(1,3)dioxole, BDBM50292475, AKOS032948633, FH72062, DA-74369, A1-06838, Q27253693, HYPOPHYLLANTHIN (CONSTITUENT OF PHYLLANTHUS AMARUS), HYPOPHYLLANTHIN (CONSTITUENT OF PHYLLANTHUS AMARUS) [DSC], Naphtho(1,2-d)-1,3-dioxole, 9-(3,4-dimethoxyphenyl)-6,7,8,9-tetrahydro-4-methoxy-7,8-bis(methoxymethyl)-, (7R,8R,9S)-, Naphtho(1,2-d)-1,3-dioxole, 9-(3,4-dimethoxyphenyl)-6,7,8,9-tetrahydro-4-methoxy-7,8-bis(methoxymethyl)-, (7S,8S,9R)-
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 64.599
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC(C2CCCC3CCC4CCCC4C32)CC1
Np Classifier Class Arylnaphthalene and aryltetralin lignans
Deep Smiles COC[C@@H]CcccOC))ccc6[C@@H][C@H]%10COC))))cccccc6)OC)))OC))))))))OCO5
Heavy Atom Count 31.0
Classyfire Class Aryltetralin lignans
Scaffold Graph Node Level C1CCC(C2CCCC3CCC4OCOC4C32)CC1
Isotope Atom Count 0.0
Molecular Complexity 560.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 3.0
Iupac Name (7R,8R,9S)-9-(3,4-dimethoxyphenyl)-4-methoxy-7,8-bis(methoxymethyl)-6,7,8,9-tetrahydrobenzo[g][1,3]benzodioxole
Veber Rule True
Classyfire Superclass Lignans, neolignans and related compounds
Xlogp 3.6
Gsk 4 400 Rule False
Molecular Formula C24H30O7
Scaffold Graph Node Bond Level c1ccc(C2CCCc3ccc4c(c32)OCO4)cc1
Inchi Key LBJCUHLNHSKZBW-XGHQBKJUSA-N
Silicos It Class Poorly soluble
Rotatable Bond Count 8.0
Synonyms hypophyllanthin
Esol Class Moderately soluble
Functional Groups COC, c1cOCO1, cOC
Compound Name Hypophyllanthin
Exact Mass 430.199
Formal Charge 0.0
Monoisotopic Mass 430.199
Hydrogen Bond Acceptor Count 7.0
Molecular Weight 430.5
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 3.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C24H30O7/c1-25-11-16-8-15-10-20(29-5)23-24(31-13-30-23)22(15)21(17(16)12-26-2)14-6-7-18(27-3)19(9-14)28-4/h6-7,9-10,16-17,21H,8,11-13H2,1-5H3/t16-,17-,21+/m0/s1
Smiles COC[C@@H]1CC2=CC(=C3C(=C2[C@@H]([C@H]1COC)C4=CC(=C(C=C4)OC)OC)OCO3)OC
Np Classifier Biosynthetic Pathway Shikimates and Phenylpropanoids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Lignans

  • 1. Outgoing r'ship FOUND_IN to/from Phyllanthus Amarus (Plant) Rel Props:Reference:https://doi.org/10.15482/usda.adc/1239279
  • 2. Outgoing r'ship FOUND_IN to/from Phyllanthus Debilis (Plant) Rel Props:Reference:ISBN:9770976605004
  • 3. Outgoing r'ship FOUND_IN to/from Phyllanthus Fraternus (Plant) Rel Props:Reference:ISBN:9788172360818; ISBN:9788172362461
  • 4. Outgoing r'ship FOUND_IN to/from Phyllanthus Niruri (Plant) Rel Props:Reference:ISBN:9788183602525
  • 5. Outgoing r'ship FOUND_IN to/from Phyllanthus Urinaria (Plant) Rel Props:Reference:ISBN:9770976605004
  • 6. Outgoing r'ship FOUND_IN to/from Phyllanthus Virgatus (Plant) Rel Props:Reference:ISBN:9770976605004