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Arctic acid

PubChem CID: 182071

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Compound Synonyms Arctic acid, 32155-99-0, UNII-R125JFP8TN, R125JFP8TN, (2,2'-Bithiophene)-5-carboxylic acid, 5'-(1-propynyl)-, (2,2'-Bithiophene)-5-carboxylic acid, 5'-(1-propyn-1-yl)-, DTXSID20185944, 5'-(Prop-1-yn-1-yl)-[2,2'-bithiophene]-5-carboxylic acid, [2,2'-Bithiophene]-5-carboxylic acid, 5'-(1-propynyl)-, Arctate, 5-(5-prop-1-ynylthiophen-2-yl)thiophene-2-carboxylic acid, DTXCID60108435, AKOS030534567, Q27287637, 5-(5-prop-1-ynyl-2-thienyl)thiophene-2-carboxylic acid, 5'-(Prop-1-yn-1-yl)-[2,2'-bithiophene]-5-carboxylicacid
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 93.8
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC(C2CCCC2)C1
Np Classifier Class Hydrocarbons
Deep Smiles CC#Cccccs5)ccccs5)C=O)O
Heavy Atom Count 16.0
Classyfire Class Bi- and oligothiophenes
Description Arctic acid, also known as arctate, is a member of the class of compounds known as bi- and oligothiophenes. Bi- and oligothiophenes are organic compounds containing two or more linked thiophene rings. Thiophene is a five-member aromatic ring with one sulfur and four carbon atoms. Arctic acid is practically insoluble (in water) and a weakly acidic compound (based on its pKa). Arctic acid can be found in burdock, which makes arctic acid a potential biomarker for the consumption of this food product.
Scaffold Graph Node Level C1CSC(C2CCCS2)C1
Isotope Atom Count 0.0
Molecular Complexity 341.0
Database Name cmaup_ingredients;fooddb_chem_all;hmdb_chem_all;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Iupac Name 5-(5-prop-1-ynylthiophen-2-yl)thiophene-2-carboxylic acid
Prediction Hob 1.0
Class Bi- and oligothiophenes
Veber Rule True
Classyfire Superclass Organoheterocyclic compounds
Xlogp 3.6
Superclass Organoheterocyclic compounds
Gsk 4 400 Rule True
Molecular Formula C12H8O2S2
Scaffold Graph Node Bond Level c1csc(-c2cccs2)c1
Prediction Swissadme 0.0
Inchi Key SJVJMFXCINSXFF-UHFFFAOYSA-N
Silicos It Class Soluble
Fcsp3 0.0833333333333333
Logs -4.051
Rotatable Bond Count 3.0
Logd 4.506
Synonyms Arctate, arctic acid
Esol Class Soluble
Functional Groups cC#CC, cC(=O)O, csc
Compound Name Arctic acid
Kingdom Organic compounds
Prediction Hob Swissadme 0.0
Exact Mass 247.997
Formal Charge 0.0
Monoisotopic Mass 247.997
Hydrogen Bond Acceptor Count 4.0
Molecular Weight 248.3
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 0.0
Total Bond Stereocenter Count 0.0
Molecular Framework Aromatic heteromonocyclic compounds
Lipinski Rule Of 5 True
Esol -4.488484000000001
Inchi InChI=1S/C12H8O2S2/c1-2-3-8-4-5-9(15-8)10-6-7-11(16-10)12(13)14/h4-7H,1H3,(H,13,14)
Smiles CC#CC1=CC=C(S1)C2=CC=C(S2)C(=O)O
Nring 8.0
Np Classifier Biosynthetic Pathway Fatty acids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Taxonomy Direct Parent Bi- and oligothiophenes
Np Classifier Superclass Fatty acyls

  • 1. Outgoing r'ship FOUND_IN to/from Arctium Lappa (Plant) Rel Props:Source_db:cmaup_ingredients;fooddb_chem_all;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Echinops Setifer (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Echinopsis Latifolius (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 4. Outgoing r'ship FOUND_IN to/from Rhaponticum Uniflorum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all