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Bocconoline

PubChem CID: 181121

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Compound Synonyms Bocconoline, 32906-88-0, (1,2-dimethoxy-12-methyl-13H-[1,3]benzodioxolo[5,6-c]phenanthridin-13-yl)methanol, 1322007-90-8, (1,2-dimethoxy-12-methyl-13H-(1,3)benzodioxolo(5,6-c)phenanthridin-13-yl)methanol, SCHEMBL3181943, CHEMBL4754766, DTXSID90954563, FS-8447, DA-51286, HY-150058, CS-0567642, E80183, (1,2-Dimethoxy-12-methyl-12,13-dihydro-9H-[1,3]benzodioxolo[5,6-c]phenanthridin-13-yl)methanol, [1,3]Benzodioxolo[5,6-c]phenanthridine-13- methanol,12,13-dihydro-1,2-dimethoxy-12- methyl-, {17,18-dimethoxy-21-methyl-5,7-dioxa-21-azapentacyclo[11.8.0.0(2),(1)?.0?,?.0(1)?,(1)?]henicosa-1(13),2,4(8),9,11,14,16,18-octaen-20-yl}methanol
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 60.4
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CC2CC3CCC4C5CCCCC5CCC4C3CC2C1
Np Classifier Class Isoquinoline alkaloids
Deep Smiles OCCcc-ccN6C))cccOCOc5cc9cc%13)))))))))))))cccc6OC)))OC
Heavy Atom Count 28.0
Classyfire Class Benzophenanthridine alkaloids
Scaffold Graph Node Level C1CCC2C(C1)CNC1C3CC4OCOC4CC3CCC21
Classyfire Subclass Dihydrobenzophenanthridine alkaloids
Isotope Atom Count 0.0
Molecular Complexity 561.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Iupac Name (1,2-dimethoxy-12-methyl-13H-[1,3]benzodioxolo[5,6-c]phenanthridin-13-yl)methanol
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 3.6
Gsk 4 400 Rule True
Molecular Formula C22H21NO5
Scaffold Graph Node Bond Level c1ccc2c(c1)CNc1c-2ccc2cc3c(cc12)OCO3
Prediction Swissadme 1.0
Inchi Key GKBDCSXIKLSKMH-UHFFFAOYSA-N
Silicos It Class Poorly soluble
Fcsp3 0.2727272727272727
Logs -6.098
Rotatable Bond Count 3.0
Logd 3.373
Synonyms bocconoline
Esol Class Moderately soluble
Functional Groups CO, c1cOCO1, cN(C)C, cOC
Compound Name Bocconoline
Prediction Hob Swissadme 1.0
Exact Mass 379.142
Formal Charge 0.0
Monoisotopic Mass 379.142
Hydrogen Bond Acceptor Count 6.0
Molecular Weight 379.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 1.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -4.685211542857143
Inchi InChI=1S/C22H21NO5/c1-23-16(10-24)20-13(6-7-17(25-2)22(20)26-3)14-5-4-12-8-18-19(28-11-27-18)9-15(12)21(14)23/h4-9,16,24H,10-11H2,1-3H3
Smiles CN1C(C2=C(C=CC(=C2OC)OC)C3=C1C4=CC5=C(C=C4C=C3)OCO5)CO
Nring 5.0
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tyrosine alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Macleaya Cordata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Zanthoxylum Nitidum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all