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Harmalacidine

PubChem CID: 179484

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Compound Synonyms Harmalacidine, 26579-69-1, Oxotetrahydronorharmine, Ketotetrahydronorharmine, Ketotetrahydronorharmin, SCHEMBL1520427, CHEMBL4059776, DTXSID20181148, AKOS024171323, 7-Methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-one, InChI=1/C12H12N2O2/c1-16-7-2-3-8-9-4-5-13-12(15)11(9)14-10(8)6-7/h2-3,6,14H,4-5H2,1H3,(H,13,15
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 54.1
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1CCCC2C1CC1CCCCC12
Np Classifier Class Carboline alkaloids
Deep Smiles COcccccc6)[nH]cc5CCNC6=O
Heavy Atom Count 16.0
Classyfire Class Indoles and derivatives
Scaffold Graph Node Level OC1NCCC2C3CCCCC3NC12
Classyfire Subclass Pyridoindoles
Isotope Atom Count 0.0
Molecular Complexity 295.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Iupac Name 7-methoxy-2,3,4,9-tetrahydropyrido[3,4-b]indol-1-one
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Organoheterocyclic compounds
Xlogp 1.7
Gsk 4 400 Rule True
Molecular Formula C12H12N2O2
Scaffold Graph Node Bond Level O=C1NCCc2c1[nH]c1ccccc21
Prediction Swissadme 0.0
Inchi Key MWEGNYFSTKOOSD-UHFFFAOYSA-N
Silicos It Class Moderately soluble
Fcsp3 0.25
Logs -4.675
Rotatable Bond Count 1.0
Logd 4.177
Synonyms harmalacidine
Esol Class Soluble
Functional Groups cC(=O)NC, cOC, c[nH]c
Compound Name Harmalacidine
Prediction Hob Swissadme 0.0
Exact Mass 216.09
Formal Charge 0.0
Monoisotopic Mass 216.09
Hydrogen Bond Acceptor Count 2.0
Molecular Weight 216.24
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 0.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -2.5767380000000006
Inchi InChI=1S/C12H12N2O2/c1-16-7-2-3-8-9-4-5-13-12(15)11(9)14-10(8)6-7/h2-3,6,14H,4-5H2,1H3,(H,13,15)
Smiles COC1=CC2=C(C=C1)C3=C(N2)C(=O)NCC3
Nring 1.0
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Peganum Harmala (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all