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5-Amino-2-[[1-[5-amino-2-[[1-[2-amino-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carbonyl]amino]-5-oxopentanoyl]pyrrolidine-2-carbonyl]amino]-5-oxopentanoic acid

PubChem CID: 17787981

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Compound Synonyms Gliadin from Wheat,, Gliadin from wheat, GLIADIN, 5-amino-2-[[1-[5-amino-2-[[1-[2-amino-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carbonyl]amino]-5-oxopentanoyl]pyrrolidine-2-carbonyl]amino]-5-oxopentanoic acid, SCHEMBL25214575, HZWWPUTXBJEENE-UHFFFAOYSA-N, Tyrosylprolylglutaminylprolylglutamine
Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 269.0
Hydrogen Bond Donor Count 7.0
Pfizer 3 75 Rule True
Scaffold Graph Level CC(CCC(C)C1CCCC1C(C)CCC1CCCCC1)C1CCCC1
Np Classifier Class Linear peptides, Tripeptides
Deep Smiles NC=O)CCCC=O)NCCCC5C=O)NCC=O)O))CCC=O)N)))))))))))))NC=O)CCCCN5C=O)CCcccccc6))O))))))N
Heavy Atom Count 45.0
Classyfire Class Carboxylic acids and derivatives
Description Isolated from wheat flour or wheat gluten Gliadin is a glycoprotein present in wheat and several other cereals within the grass genus Triticum. Gliadins are prolamins and are separated on the basis of electrophoretic mobility and isoelectric focusing. Gliadin is found in wheat, cereals and cereal products, and common wheat.
Scaffold Graph Node Level OC(NCC(O)N1CCCC1)C1CCCN1C(O)CCC1CCCCC1
Classyfire Subclass Amino acids, peptides, and analogues
Isotope Atom Count 0.0
Molecular Complexity 1130.0
Database Name cmaup_ingredients;fooddb_chem_all;hmdb_chem_all;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Iupac Name 5-amino-2-[[1-[5-amino-2-[[1-[2-amino-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carbonyl]amino]-5-oxopentanoyl]pyrrolidine-2-carbonyl]amino]-5-oxopentanoic acid
Prediction Hob 0.0
Class Carboxylic acids and derivatives
Veber Rule False
Classyfire Superclass Organic acids and derivatives
Xlogp -4.5
Superclass Organic acids and derivatives
Subclass Amino acids, peptides, and analogues
Gsk 4 400 Rule False
Molecular Formula C29H41N7O9
Scaffold Graph Node Bond Level O=C(NCC(=O)N1CCCC1)C1CCCN1C(=O)CCc1ccccc1
Prediction Swissadme 0.0
Inchi Key HZWWPUTXBJEENE-UHFFFAOYSA-N
Silicos It Class Soluble
Fcsp3 0.5517241379310345
Logs -2.213
Rotatable Bond Count 15.0
Logd -1.758
Synonyms Gliadins, alpha Gliadin, alpha-Gliadin, Tyr-pro-GLN-pro-GLN, alpha-Gliadin (43-47), Gliadin, Gliadophorin (43-47), gliadin, prolamines (gliadins)
Esol Class Highly soluble
Functional Groups CC(=O)N(C)C, CC(=O)O, CC(N)=O, CN, CNC(C)=O, cO
Compound Name 5-Amino-2-[[1-[5-amino-2-[[1-[2-amino-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carbonyl]amino]-5-oxopentanoyl]pyrrolidine-2-carbonyl]amino]-5-oxopentanoic acid
Kingdom Organic compounds
Prediction Hob Swissadme 0.0
Exact Mass 631.297
Formal Charge 0.0
Monoisotopic Mass 631.297
Hydrogen Bond Acceptor Count 10.0
Molecular Weight 631.7
Gi Absorption False
Covalent Unit Count 1.0
Total Atom Stereocenter Count 5.0
Total Bond Stereocenter Count 0.0
Molecular Framework Aromatic heteromonocyclic compounds
Lipinski Rule Of 5 False
Esol -1.4983260666666673
Inchi InChI=1S/C29H41N7O9/c30-18(15-16-5-7-17(37)8-6-16)27(42)35-13-1-3-21(35)25(40)33-19(9-11-23(31)38)28(43)36-14-2-4-22(36)26(41)34-20(29(44)45)10-12-24(32)39/h5-8,18-22,37H,1-4,9-15,30H2,(H2,31,38)(H2,32,39)(H,33,40)(H,34,41)(H,44,45)
Smiles C1CC(N(C1)C(=O)C(CCC(=O)N)NC(=O)C2CCCN2C(=O)C(CC3=CC=C(C=C3)O)N)C(=O)NC(CCC(=O)N)C(=O)O
Nring 3.0
Np Classifier Biosynthetic Pathway Amino acids and Peptides
Defined Bond Stereocenter Count 0.0
Egan Rule False
Taxonomy Direct Parent Oligopeptides
Np Classifier Superclass Oligopeptides, Small peptides

  • 1. Outgoing r'ship FOUND_IN to/from Centipeda Minima (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Fagopyrum Esculentum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Oryza Sativa (Plant) Rel Props:Reference:ISBN:9788172362140
  • 4. Outgoing r'ship FOUND_IN to/from Secale Cereale (Plant) Rel Props:Reference:ISBN:9780387706375
  • 5. Outgoing r'ship FOUND_IN to/from Triticum Aestivum (Plant) Rel Props:Source_db:fooddb_chem_all