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(1R)-6-Methoxy-1-((4-methoxyphenyl)methyl)-2-methyl-3,4-dihydro-1H-isoquinolin-7-ol

PubChem CID: 177088

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Compound Synonyms 19879-50-6, (1R)-6-Methoxy-1-((4-methoxyphenyl)methyl)-2-methyl-3,4-dihydro-1H-isoquinolin-7-ol, (1R)-6-methoxy-1-[(4-methoxyphenyl)methyl]-2-methyl-3,4-dihydro-1H-isoquinolin-7-ol, 7-Isoquinolinol, 1,2,3,4-tetrahydro-6-methoxy-1-[(4-methoxyphenyl)methyl]-2-methyl-, (1R)-, N-Demethylcolletine, R-N-Demethylcollettine, (-)-N-Demethylcolletine, DTXSID90173631
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 41.9
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC(CC2CCCC3CCCCC32)CC1
Np Classifier Class Isoquinoline alkaloids, Tetrahydroisoquinoline alkaloids
Deep Smiles COcccccc6))C[C@H]NC)CCcc6ccO)cc6)OC
Heavy Atom Count 23.0
Classyfire Class Isoquinolines and derivatives
Scaffold Graph Node Level C1CCC(CC2NCCC3CCCCC32)CC1
Classyfire Subclass Benzylisoquinolines
Isotope Atom Count 0.0
Molecular Complexity 370.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 1.0
Iupac Name (1R)-6-methoxy-1-[(4-methoxyphenyl)methyl]-2-methyl-3,4-dihydro-1H-isoquinolin-7-ol
Veber Rule True
Classyfire Superclass Organoheterocyclic compounds
Xlogp 3.4
Gsk 4 400 Rule True
Molecular Formula C19H23NO3
Scaffold Graph Node Bond Level c1ccc(CC2NCCc3ccccc32)cc1
Inchi Key DLDZDBDYUZLISX-QGZVFWFLSA-N
Silicos It Class Moderately soluble
Rotatable Bond Count 4.0
Synonyms 4'methyl-n-methylcoclaurine
Esol Class Moderately soluble
Functional Groups CN(C)C, cO, cOC
Compound Name (1R)-6-Methoxy-1-((4-methoxyphenyl)methyl)-2-methyl-3,4-dihydro-1H-isoquinolin-7-ol
Exact Mass 313.168
Formal Charge 0.0
Monoisotopic Mass 313.168
Hydrogen Bond Acceptor Count 4.0
Molecular Weight 313.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 1.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C19H23NO3/c1-20-9-8-14-11-19(23-3)18(21)12-16(14)17(20)10-13-4-6-15(22-2)7-5-13/h4-7,11-12,17,21H,8-10H2,1-3H3/t17-/m1/s1
Smiles CN1CCC2=CC(=C(C=C2[C@H]1CC3=CC=C(C=C3)OC)O)OC
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tyrosine alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Nelumbo Nucifera (Plant) Rel Props:Reference:https://doi.org/10.15482/usda.adc/1239279