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Venalstonidine

PubChem CID: 176438

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Compound Synonyms 26619-93-2, Venalstonidine, (-)-Venalstonidine, 6,7-Epoxykopsinine, DTXSID90949454, Methyl 6,7-epoxyaspidofractinine-21-carboxylate, 4H,11aH-1b,3a-Ethano-12H-oxireno(6,7)indolizino(8,1-cd)carbazole-3-carboxylic acid, 1a,2,3,9,10,12a-hexahydro-, methyl ester, (1aR,1bS,3R,3aR,8bR,11aR,12aS)-
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 54.1
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC2C(C1)CC13CCC4(CC1)C1CC1CC1CCC23C14
Np Classifier Class Aspidosperma type
Deep Smiles COC=O)[C@@H]C[C@@]CC[C@@]6NccC5[C@H]9NCC5))C[C@H][C@@H]%13O3)))))))cccc6
Heavy Atom Count 26.0
Classyfire Class Aspidofractine alkaloids
Scaffold Graph Node Level C1CCC2C(C1)NC13CCC4(CC1)C1OC1CN1CCC23C14
Isotope Atom Count 0.0
Molecular Complexity 699.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 6.0
Iupac Name methyl (1S,2R,4S,17R,18R,22R)-3-oxa-6,16-diazaheptacyclo[15.2.2.11,6.02,4.09,17.010,15.09,22]docosa-10,12,14-triene-18-carboxylate
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 2.0
Gsk 4 400 Rule True
Molecular Formula C21H24N2O3
Scaffold Graph Node Bond Level c1ccc2c(c1)NC13CCC4(CC1)C1OC1CN1CCC23C14
Inchi Key PKVIZXKEMISSGB-JDGDXTPDSA-N
Silicos It Class Moderately soluble
Rotatable Bond Count 2.0
Synonyms venalstonidine
Esol Class Soluble
Functional Groups CN(C)C, COC(C)=O, C[C@@H]1O[C@@H]1C, cNC
Compound Name Venalstonidine
Exact Mass 352.179
Formal Charge 0.0
Monoisotopic Mass 352.179
Hydrogen Bond Acceptor Count 5.0
Molecular Weight 352.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 7.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C21H24N2O3/c1-25-17(24)13-10-19-6-7-21(13)20(12-4-2-3-5-14(12)22-21)8-9-23(18(19)20)11-15-16(19)26-15/h2-5,13,15-16,18,22H,6-11H2,1H3/t13-,15-,16-,18-,19+,20?,21+/m0/s1
Smiles COC(=O)[C@@H]1C[C@@]23CC[C@]14C5([C@H]2N(CC5)C[C@H]6[C@@H]3O6)C7=CC=CC=C7N4
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Alstonia Venenata (Plant) Rel Props:Reference:ISBN:9788172360481; ISBN:9788185042053