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12-Deoxyphorbol-13,20-diacetate

PubChem CID: 16760073

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Compound Synonyms 12-deoxyphorbol-13,20-diacetate, 12-Deoxyphorbol diacetate, 25090-76-0, CHEBI:69819, [(1R,2S,6R,10S,11R,13S,15R)-13-acetyloxy-1,6-dihydroxy-4,12,12,15-tetramethyl-5-oxo-8-tetracyclo[8.5.0.02,6.011,13]pentadeca-3,8-dienyl]methyl acetate, 5H-Cyclopropa(3,4)benz(1,2-c)azulen-5-one, 9a-(acetyloxy)-3-((acetyloxy)methyl)-1,1a,1b,4,4a,7a,7b,8,9,9a-decahydro-4a,7b-dihydroxy-1,1,6,8-tetramethyl-, (1aR-(1aalpha,1bbeta,4abeta,7aalpha,7balpha,8alpha,9aalpha))-, CHEMBL1813584, SCHEMBL12209637, NCGC00163536-01, SR-05000002353, SR-05000002353-2, Q27138160
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 110.0
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule True
Scaffold Graph Level CC1CCC2C1CCCC1C3CC3CCC21
Np Classifier Class Tetracyclic diterpenoids, Tigliane diterpenoids
Deep Smiles CC=O)OCC=C[C@H][C@H][C@@]C3C)C))OC=O)C)))C[C@H][C@@]6[C@H][C@@]C%11)O)C=O)C=C5)C)))))O))C
Heavy Atom Count 31.0
Classyfire Class Prenol lipids
Scaffold Graph Node Level OC1CCC2C1CCCC1C3CC3CCC21
Classyfire Subclass Diterpenoids
Isotope Atom Count 0.0
Molecular Complexity 930.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 7.0
Uniprot Id Q96QE3, P27695
Iupac Name [(1R,2S,6R,10S,11R,13S,15R)-13-acetyloxy-1,6-dihydroxy-4,12,12,15-tetramethyl-5-oxo-8-tetracyclo[8.5.0.02,6.011,13]pentadeca-3,8-dienyl]methyl acetate
Prediction Hob 0.0
Veber Rule True
Classyfire Superclass Lipids and lipid-like molecules
Xlogp 1.3
Gsk 4 400 Rule False
Molecular Formula C24H32O7
Scaffold Graph Node Bond Level O=C1C=CC2C1CC=CC1C3CC3CCC21
Prediction Swissadme 1.0
Inchi Key NFSCEXJSMYPVGG-BACQOSNCSA-N
Silicos It Class Soluble
Fcsp3 0.7083333333333334
Logs -4.052
Rotatable Bond Count 5.0
Logd 2.119
Synonyms 12-deoxyphorbol-13,20-diacetate
Esol Class Soluble
Functional Groups CC(=O)OC, CC(C)=CC, CC1=CCCC1=O, CO, COC(C)=O
Compound Name 12-Deoxyphorbol-13,20-diacetate
Prediction Hob Swissadme 0.0
Exact Mass 432.215
Formal Charge 0.0
Monoisotopic Mass 432.215
Hydrogen Bond Acceptor Count 7.0
Molecular Weight 432.5
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 7.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -2.9979806000000013
Inchi InChI=1S/C24H32O7/c1-12-7-18-22(28,20(12)27)10-16(11-30-14(3)25)8-17-19-21(5,6)23(19,31-15(4)26)9-13(2)24(17,18)29/h7-8,13,17-19,28-29H,9-11H2,1-6H3/t13-,17+,18-,19-,22-,23+,24-/m1/s1
Smiles C[C@@H]1C[C@@]2([C@@H](C2(C)C)[C@H]3[C@]1([C@@H]4C=C(C(=O)[C@]4(CC(=C3)COC(=O)C)O)C)O)OC(=O)C
Nring 4.0
Np Classifier Biosynthetic Pathway Terpenoids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Diterpenoids

  • 1. Outgoing r'ship FOUND_IN to/from Euphorbia Fischeriana (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Euphorbia Milii (Plant) Rel Props:Reference:ISBN:9788185042114
  • 3. Outgoing r'ship FOUND_IN to/from Euphorbia Thymifolia (Plant) Rel Props:Reference:ISBN:9788171360536; ISBN:9788172360818