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Meglutol

PubChem CID: 1662

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Compound Synonyms MEGLUTOL, 503-49-1, 3-Hydroxy-3-methylglutaric acid, 3-Hydroxy-3-methylpentanedioic acid, Dicrotalic acid, Lipoglutaren, Pentanedioic acid, 3-hydroxy-3-methyl-, Medroglutaric acid, beta-Hydroxy-beta-methylglutaric acid, Meglutolum, 3-hydroxy-3-methyl-glutaric acid, HMGA, CB 337, Meglutol [USAN:INN], Meglutolum [INN-Latin], CB-337, 3-Hydroxy-3-methylglutarate, Glutaric acid, 3-hydroxy-3-methyl-, EINECS 207-971-1, CLA99KCD53, (S)-Meglutol, NSC 361411, NSC-361411, BRN 1769194, 3-Hydorxy-3-methylglutaric acid, CHEBI:16831, beta-Hydroxy-beta-Methylglutarate, 3-Hydroxymethylglutarate, MEGLUTOL [USAN], MEGLUTOL [INN], MEGLUTOL [MI], MEGLUTOL [MART.], CHEMBL50444, 3-Hydroxy-3-methylpentane-1,5-dioic Acid, HMG, DTXSID90198304, 4-03-00-01166 (Beilstein Handbook Reference), (S)-3-Hydroxy-3-methylglutaric acid, Meglutolum (INN-Latin), MEGLUTOL (MART.), Dicrotalic acid, 3-Hydroxy-3-methylglutaric acid, (S)-3-Hydroxy-3-methylglutarate, MFCD00002712, UNII-CLA99KCD53, meglutolo, Dicrotalate, Menotrophin?, Meglutol (USAN/INN), bmse000335, b-Hydroxy-b-methylglutarate, 3-Methyl-3-hydroxyglutarate, SCHEMBL28443, MLS001066390, b-Hydroxy-b-methylglutaric acid, GTPL2960, MEGxp0_001907, 3 Hydroxy 3 methylglutaric Acid, 3-Methyl-3-hydroxyglutaric acid, ACon1_000502, beta Hydroxy beta Methylglutarate, C10AX05, DTXCID80120795, Acid, 3-Hydroxy-3-methylglutaric, HMS3264B09, Pharmakon1600-01506183, HY-B1189, 3 Hydroxy 3 methylpentanedioic Acid, 3-HYDROXY-3-METHYLPENTANE-1, BDBM50160720, NSC361411, NSC760412, Acid, 3-Hydroxy-3-methylpentanedioic, AKOS000280741, CCG-213633, CS-4798, DB04377, FH57974, NSC-760412, NCGC00169018-01, AS-63885, GLUTARIC ACID, BETA-HYDROXY METHYL, SMR000471861, 3-Hydroxy-3-methylglutaric acid, >=95%, DB-071173, H0436, NS00014740, (3R)-3,5,5-trihydroxy-3-methylpentanoic acid, C03761, D04897, F17049, AB00698060_04, Dicrotalic acid, 3-Hydroxy-3-methylglutaric acid, Q524670, SR-01000763754, 3-Hydroxy-3-methylpentane-1 pound not5-dioic Acid, SR-01000763754-2, A90FC159-16ED-49CA-9A7F-D90B0A5B3EBC, BRD-K00495673-001-05-2, 3-Hydroxy-3-methylglutaric acid, purum, >=95.0% (GC), 3-Hydroxy-3-methyl-pentanedioic acid, 3-Hydroxy-3-methyl-glutaric acid, 207-971-1, XII
Topological Polar Surface Area 94.8
Hydrogen Bond Donor Count 3.0
Heavy Atom Count 11.0
Description 3-hydroxymethylglutaric acid, also known as meglutol or dicrotalic acid, is a member of the class of compounds known as hydroxy fatty acids. Hydroxy fatty acids are fatty acids in which the chain bears a hydroxyl group. 3-hydroxymethylglutaric acid is soluble (in water) and a weakly acidic compound (based on its pKa). 3-hydroxymethylglutaric acid can be synthesized from glutaric acid. 3-hydroxymethylglutaric acid is also a parent compound for other transformation products, including but not limited to, viscumneoside VII, viscumneoside IV, and yanuthone D. 3-hydroxymethylglutaric acid can be found in flaxseed, which makes 3-hydroxymethylglutaric acid a potential biomarker for the consumption of this food product. 3-hydroxymethylglutaric acid can be found primarily in saliva and urine. 3-hydroxymethylglutaric acid is a non-carcinogenic (not listed by IARC) potentially toxic compound. Chronically high levels of 3-hydroxymethylglutaric acid are associated with the inborn error of metabolism: 3-Hydroxy-3-Methylglutaryl-CoA Lyase Deficiency (T3DB).
Isotope Atom Count 0.0
Molecular Complexity 158.0
Database Name cmaup_ingredients;fooddb_chem_all;hmdb_chem_all;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Uniprot Id P35914, P51639, P04035, P0DTD1, n.a.
Iupac Name 3-hydroxy-3-methylpentanedioic acid
Prediction Hob 1.0
Class Fatty Acyls
Target Id NPT253
Xlogp -1.2
Superclass Lipids and lipid-like molecules
Subclass Fatty acids and conjugates
Molecular Formula C6H10O5
Prediction Swissadme 0.0
Inchi Key NPOAOTPXWNWTSH-UHFFFAOYSA-N
Fcsp3 0.6666666666666666
Logs 0.429
Rotatable Bond Count 4.0
State Solid
Logd -0.761
Synonyms (S)-3-Hydroxy-3-methylglutaric acid, (S)-Meglutol, 3-HYDROXY-3-methyl-glutarIC ACID, 3-Hydroxy-3-methylpentanedioic acid, beta-Hydroxy-beta-methylglutaric acid, Dicrotalic acid, Meglutol, Meglutolum, 3-Hydorxy-3-methylglutaric acid, (S)-3-Hydroxy-3-methylglutarate, 3-HYDROXY-3-methyl-glutarate, 3-Hydroxy-3-methylpentanedioate, b-Hydroxy-b-methylglutarate, b-Hydroxy-b-methylglutaric acid, beta-Hydroxy-beta-methylglutarate, Β-hydroxy-β-methylglutarate, Β-hydroxy-β-methylglutaric acid, Dicrotalate, 3-Hydorxy-3-methylglutarate, 3-Hydroxymethylglutarate, 3-Hydroxy-3-methylglutarate, 3-Hydroxy-3-methylglutaric acid, 3-Methyl-3-hydroxyglutarate, 3-Methyl-3-hydroxyglutaric acid, CB 337, 3 Hydroxy 3 methylpentanedioic acid, Acid, 3-hydroxy-3-methylglutaric, Acid, 3-hydroxy-3-methylpentanedioic, beta Hydroxy beta methylglutarate, 3 Hydroxy 3 methylglutaric acid, 3-Methyl-3-hydroxypentanedioate, 3-Methyl-3-hydroxypentanedioic acid, HMG, HMGA, Lipoglutaren, Medroglutarate, Medroglutaric acid
Compound Name Meglutol
Kingdom Organic compounds
Prediction Hob Swissadme 0.0
Exact Mass 162.053
Formal Charge 0.0
Monoisotopic Mass 162.053
Hydrogen Bond Acceptor Count 5.0
Molecular Weight 162.14
Covalent Unit Count 1.0
Total Atom Stereocenter Count 0.0
Total Bond Stereocenter Count 0.0
Molecular Framework Aliphatic acyclic compounds
Esol 0.18102580000000013
Inchi InChI=1S/C6H10O5/c1-6(11,2-4(7)8)3-5(9)10/h11H,2-3H2,1H3,(H,7,8)(H,9,10)
Smiles CC(CC(=O)O)(CC(=O)O)O
Nring 0.0
Defined Bond Stereocenter Count 0.0
Taxonomy Direct Parent Hydroxy fatty acids

  • 1. Outgoing r'ship FOUND_IN to/from Avena Sativa (Plant) Rel Props:Source_db:fooddb_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Linum Usitatissimum (Plant) Rel Props:Source_db:fooddb_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Pogostemon Cablin (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all