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Deoxytubulosine

PubChem CID: 165003

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Compound Synonyms Deoxytubulosine, 10,11-Dimethoxytubulosan, 2632-30-6, Tubulosan, 10,11-dimethoxy-, (2S,3R,11bS)-3-ethyl-9,10-dimethoxy-2-[[(1R)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl]methyl]-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizine, C11817, 2H-Benzo[a]quinolizine, 3-ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2-[[(1R)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl]methyl]-, (2S,3R,11bS)-, AC1L4VWR, AC1Q56PD, CHEBI:4433, CHEMBL4212545, DTXSID10949173, Q27106381
Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 49.5
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC2C(C1)CCC1CCC(CC3CCCC4C5CCCCC5CC34)CC12
Np Classifier Class Carboline alkaloids, Isoquinoline alkaloids, Terpenoid tetrahydroisoquinoline alkaloids
Deep Smiles CC[C@H]CNCCcc[C@@H]6C[C@@H]%10C[C@H]NCCcc6[nH]cc5cccc6)))))))))))))))))cccc6)OC)))OC
Heavy Atom Count 34.0
Classyfire Class Harmala alkaloids
Scaffold Graph Node Level C1CCC2C(C1)CCN1CCC(CC3NCCC4C5CCCCC5NC34)CC21
Isotope Atom Count 0.0
Molecular Complexity 690.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 4.0
Iupac Name (2S,3R,11bS)-3-ethyl-9,10-dimethoxy-2-[[(1R)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl]methyl]-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizine
Prediction Hob 0.0
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 5.0
Gsk 4 400 Rule False
Molecular Formula C29H37N3O2
Scaffold Graph Node Bond Level c1ccc2c(c1)CCN1CCC(CC3NCCc4c3[nH]c3ccccc43)CC21
Prediction Swissadme 1.0
Inchi Key AVJZNOIWPGXYKM-LXFCCGDJSA-N
Silicos It Class Poorly soluble
Fcsp3 0.5172413793103449
Logs -3.346
Rotatable Bond Count 5.0
Logd 4.383
Synonyms deoxytubulosine
Esol Class Moderately soluble
Functional Groups CN(C)C, CNC, cOC, c[nH]c
Compound Name Deoxytubulosine
Prediction Hob Swissadme 0.0
Exact Mass 459.289
Formal Charge 0.0
Monoisotopic Mass 459.289
Hydrogen Bond Acceptor Count 4.0
Molecular Weight 459.6
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 4.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -5.811001388235295
Inchi InChI=1S/C29H37N3O2/c1-4-18-17-32-12-10-19-15-27(33-2)28(34-3)16-23(19)26(32)14-20(18)13-25-29-22(9-11-30-25)21-7-5-6-8-24(21)31-29/h5-8,15-16,18,20,25-26,30-31H,4,9-14,17H2,1-3H3/t18-,20-,25+,26-/m0/s1
Smiles CC[C@H]1CN2CCC3=CC(=C(C=C3[C@@H]2C[C@@H]1C[C@@H]4C5=C(CCN4)C6=CC=CC=C6N5)OC)OC
Nring 6.0
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids, Tyrosine alkaloids