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Domesticine

PubChem CID: 164611

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Compound Synonyms Domesticine, 476-71-1, 96P7649HX8, (12S)-18-methoxy-13-methyl-5,7-dioxa-13-azapentacyclo[10.7.1.02,10.04,8.016,20]icosa-1(20),2,4(8),9,16,18-hexaen-19-ol, CCRIS 3824, Nordomesticine, UNII-96P7649HX8, D-DOMESTICINE, DOMESTICINE [MI], (+)-DOMESTICINE, CHEMBL1808240, DTXSID50197217, CHEBI:178226, C19980, Q15634032, 1-HYDROXY-2-METHOXY-9,10-METHYLENEDIOXYAPORPHINE, 4H-BENZO(DE)(1,3)BENZODIOXOLO(5,6-G)QUINOLIN-1-OL, 5,6,6A,7-TETRAHYDRO-2-METHOXY-6-METHYL-, (6AS)-
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 51.2
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CC2CC3CC4CCCC5CCCC(C3CC2C1)C54
Np Classifier Class Aporphine alkaloids, Isoquinoline alkaloids
Deep Smiles COcccCCN[C@@H]c6c-cccOCOc5cc9C%13))))))))))c%10O)))))C
Heavy Atom Count 24.0
Classyfire Class Aporphines
Scaffold Graph Node Level C1CC2CCNC3CC4CC5OCOC5CC4C(C1)C23
Isotope Atom Count 0.0
Molecular Complexity 488.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 1.0
Iupac Name (12S)-18-methoxy-13-methyl-5,7-dioxa-13-azapentacyclo[10.7.1.02,10.04,8.016,20]icosa-1(20),2,4(8),9,16,18-hexaen-19-ol
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 2.9
Gsk 4 400 Rule True
Molecular Formula C19H19NO4
Scaffold Graph Node Bond Level c1cc2c3c(c1)-c1cc4c(cc1CC3NCC2)OCO4
Prediction Swissadme 1.0
Inchi Key ZMNSHBTYBQNBPV-ZDUSSCGKSA-N
Silicos It Class Moderately soluble
Fcsp3 0.3684210526315789
Logs -3.207
Rotatable Bond Count 1.0
Logd 2.818
Synonyms domesticine
Esol Class Moderately soluble
Functional Groups CN(C)C, c1cOCO1, cO, cOC
Compound Name Domesticine
Prediction Hob Swissadme 1.0
Exact Mass 325.131
Formal Charge 0.0
Monoisotopic Mass 325.131
Hydrogen Bond Acceptor Count 5.0
Molecular Weight 325.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 1.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -4.000856800000001
Inchi InChI=1S/C19H19NO4/c1-20-4-3-10-6-16(22-2)19(21)18-12-8-15-14(23-9-24-15)7-11(12)5-13(20)17(10)18/h6-8,13,21H,3-5,9H2,1-2H3/t13-/m0/s1
Smiles CN1CCC2=CC(=C(C3=C2[C@@H]1CC4=CC5=C(C=C43)OCO5)O)OC
Nring 5.0
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tyrosine alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Corydalis Cornuta (Plant) Rel Props:Reference:ISBN:9788185042084; ISBN:9788185042114
  • 2. Outgoing r'ship FOUND_IN to/from Nandina Domestica (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all