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Homodestruxin B

PubChem CID: 163819

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Compound Synonyms Homodestruxin B, Homo-destruxin B, 110538-19-7, (3R,10S,16S,19S)-13,16-bis[(2S)-butan-2-yl]-10,11,14-trimethyl-3-(2-methylpropyl)-4-oxa-1,8,11,14,17-pentazabicyclo[17.3.0]docosane-2,5,9,12,15,18-hexone, DTXSID40911727, Destruxin B, 3-(N-methyl-L-isoleucine)-, 3,6-Di(butan-2-yl)-1,10-dihydroxy-5,8,9-trimethyl-16-(2-methylpropyl)-5,6,8,9,12,13,19,20,21,21a-decahydropyrrolo[1,2-d][1,4,7,10,13,16]oxapentaazacyclononadecine-4,7,14,17(3H,16H)-tetrone
Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 145.0
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule True
Scaffold Graph Level CC1CCCC(C)CCC(C)C2CCCC2C(C)CCC(C)CCC(C)CC1
Np Classifier Class Cyclic peptides, Depsipeptides
Deep Smiles CC[C@@H][C@@H]NC=O)[C@@H]CCCN5C=O)[C@@H]CCC)C)))OC=O)CCNC=O)[C@@H]NC=O)CNC%22=O))C))[C@H]CC))C))))C))C))))))))))))))))))C
Heavy Atom Count 43.0
Classyfire Class Peptidomimetics
Scaffold Graph Node Level OC1CNC(O)CNC(O)CNC(O)C2CCCN2C(O)COC(O)CCN1
Classyfire Subclass Depsipeptides
Isotope Atom Count 0.0
Molecular Complexity 1030.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 6.0
Iupac Name (3R,10S,16S,19S)-13,16-bis[(2S)-butan-2-yl]-10,11,14-trimethyl-3-(2-methylpropyl)-4-oxa-1,8,11,14,17-pentazabicyclo[17.3.0]docosane-2,5,9,12,15,18-hexone
Veber Rule True
Classyfire Superclass Organic acids and derivatives
Xlogp 3.2
Gsk 4 400 Rule False
Molecular Formula C31H53N5O7
Scaffold Graph Node Bond Level O=C1CNC(=O)CNC(=O)CNC(=O)C2CCCN2C(=O)COC(=O)CCN1
Inchi Key WWALEZSSEHJILM-GNUKRQLOSA-N
Silicos It Class Moderately soluble
Rotatable Bond Count 6.0
Synonyms homodestruxin b
Esol Class Moderately soluble
Functional Groups CC(=O)N(C)C, CC(=O)OC, CN(C)C(C)=O, CNC(C)=O
Compound Name Homodestruxin B
Exact Mass 607.394
Formal Charge 0.0
Monoisotopic Mass 607.394
Hydrogen Bond Acceptor Count 7.0
Molecular Weight 607.8
Gi Absorption False
Covalent Unit Count 1.0
Total Atom Stereocenter Count 7.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C31H53N5O7/c1-10-19(5)25-30(41)35(9)26(20(6)11-2)31(42)34(8)21(7)27(38)32-15-14-24(37)43-23(17-18(3)4)29(40)36-16-12-13-22(36)28(39)33-25/h18-23,25-26H,10-17H2,1-9H3,(H,32,38)(H,33,39)/t19-,20-,21-,22-,23+,25-,26?/m0/s1
Smiles CC[C@H](C)[C@H]1C(=O)N(C(C(=O)N([C@H](C(=O)NCCC(=O)O[C@@H](C(=O)N2CCC[C@H]2C(=O)N1)CC(C)C)C)C)[C@@H](C)CC)C
Np Classifier Biosynthetic Pathway Amino acids and Peptides, Polyketides
Defined Bond Stereocenter Count 0.0
Egan Rule False
Np Classifier Superclass Oligopeptides

  • 1. Outgoing r'ship FOUND_IN to/from Brassica Rapa (Plant) Rel Props:Reference:ISBN:9788172362089