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Homolycorine

PubChem CID: 160473

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Compound Synonyms Homolycorine, 477-20-3, 9,10-Dimethoxy-1-methyllycorenan-7-one, (5aR,11bS,11cS)-9,10-dimethoxy-1-methyl-2,3,5,5a,11b,11c-hexahydroisochromeno[3,4-g]indol-7-one, T95J9AUU63, Lycorenan-7-one, 9,10-dimethoxy-1-methyl-, DTXSID80963902, (+)-homolycorine, (5aR,11bS,11cS)-9,10-dimethoxy-1-methyl-2,3,5,5a,11b,11c-hexahydroisochromeno(3,4-g)indol-7-one, NARCIPOETINE, UNII-T95J9AUU63, SCHEMBL4373999, CHEMBL1221973, DTXCID901391627, NS00094207, Q18349931, (1S,10R,17S)-4,5-dimethoxy-16-methyl-9-oxa-16-azatetracyclo[8.7.0.0{2,7}.0{13,17}]heptadeca-2,4,6,12-tetraen-8-one, (2)BENZOPYRANO(3,4-G)INDOL-7(1H)-ONE, 2,3,5,5A,11B,11C-HEXAHYDRO-9,10-DIMETHOXY-1-METHYL-, (5AR-(5A.ALPHA.,11B.ALPHA.,11C.BETA.))-, (5AR,11BS,11CS)-2,3,5,5A,11B,11C-HEXAHYDRO-9,10-DIMETHOXY-1-METHYL(2)BENZOPYRANO(3,4-G)INDOL-7(1H)-ONE, [2]Benzopyrano[3,4-g]indol-7(1H)-one, 2,3,5,5a,11b,11c-hexahydro-9,10-dimethoxy-1-methyl-, (5aR,11bS,11cS)-
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 48.0
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1CC2CCC3CCCC3C2C2CCCCC12
Np Classifier Class Amarylidaceae alkaloids
Deep Smiles COccc[C@@H][C@@H]CC=C[C@H]6NC)CC5)))))))OC=O)c6cc%10OC
Heavy Atom Count 23.0
Classyfire Class Amaryllidaceae alkaloids
Scaffold Graph Node Level OC1OC2CCC3CCNC3C2C2CCCCC12
Classyfire Subclass Homolycorine-type amaryllidaceae alkaloids
Isotope Atom Count 0.0
Molecular Complexity 519.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 3.0
Iupac Name (5aR,11bS,11cS)-9,10-dimethoxy-1-methyl-2,3,5,5a,11b,11c-hexahydroisochromeno[3,4-g]indol-7-one
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 2.0
Gsk 4 400 Rule True
Molecular Formula C18H21NO4
Scaffold Graph Node Bond Level O=C1OC2CC=C3CCNC3C2c2ccccc21
Prediction Swissadme 1.0
Inchi Key WXZAKVLYZHWSNF-KBRIMQKVSA-N
Silicos It Class Soluble
Fcsp3 0.5
Logs -3.653
Rotatable Bond Count 2.0
Logd 2.157
Synonyms homolycorine
Esol Class Soluble
Functional Groups CC=C(C)C, CN(C)C, cC(=O)OC, cOC
Compound Name Homolycorine
Prediction Hob Swissadme 1.0
Exact Mass 315.147
Formal Charge 0.0
Monoisotopic Mass 315.147
Hydrogen Bond Acceptor Count 5.0
Molecular Weight 315.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 3.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -3.0973808782608696
Inchi InChI=1S/C18H21NO4/c1-19-7-6-10-4-5-13-16(17(10)19)11-8-14(21-2)15(22-3)9-12(11)18(20)23-13/h4,8-9,13,16-17H,5-7H2,1-3H3/t13-,16-,17-/m1/s1
Smiles CN1CCC2=CC[C@@H]3[C@H]([C@@H]21)C4=CC(=C(C=C4C(=O)O3)OC)OC
Nring 4.0
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tyrosine alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Achillea Wilsoniana (Plant) Rel Props:Source_db:npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Amaryllidaceae (Plant) Rel Props:Source_db:cmaup_ingredients
  • 3. Outgoing r'ship FOUND_IN to/from Cassia Sieberiana (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 4. Outgoing r'ship FOUND_IN to/from Crinum Viviparum (Plant) Rel Props:Reference:ISBN:9788172362140
  • 5. Outgoing r'ship FOUND_IN to/from Ferula Persica (Plant) Rel Props:Source_db:npass_chem_all
  • 6. Outgoing r'ship FOUND_IN to/from Juniperus Procera (Plant) Rel Props:Source_db:npass_chem_all
  • 7. Outgoing r'ship FOUND_IN to/from Ligularia Przewalskii (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 8. Outgoing r'ship FOUND_IN to/from Linum Perenne (Plant) Rel Props:Source_db:npass_chem_all
  • 9. Outgoing r'ship FOUND_IN to/from Lycoris Radiata (Plant) Rel Props:Reference:https://doi.org/10.15482/usda.adc/1239279
  • 10. Outgoing r'ship FOUND_IN to/from Narcissus Tazetta (Plant) Rel Props:Reference:ISBN:9788185042145
  • 11. Outgoing r'ship FOUND_IN to/from Stachys Aegyptiaca (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all