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Methyl Aristolate

PubChem CID: 160246

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Compound Synonyms Methyl aristolate, 35142-06-4, Aristolic acid methyl ester, CCRIS 2994, DYZ33R9ED7, methyl 8-methoxynaphtho[2,1-g][1,3]benzodioxole-5-carboxylate, DTXSID00188635, 8-Methoxyphenanthro(3,4-d)-1,3-dioxole-5-carboxylic acid methyl ester, 8-Methoxyphenanthro(3,4-d)-1,3-dioxole-5-carboxylic acid, methyl ester, Phenanthro(3,4-d)-1,3-dioxole-5-carboxylic acid, 8-methoxy-, methyl ester, methyl 8-methoxynaphtho(2,1-g)(1,3)benzodioxole-5-carboxylate, Methyl 6-methoxy-14,16-dioxatetracyclo(8.7.0.0,.0,)heptadeca-1(10),2(7),3,5,8,11,13(17)-heptaene-11-carboxylic acid, Methyl 6-methoxy-14,16-dioxatetracyclo[8.7.0.0,.0,]heptadeca-1(10),2(7),3,5,8,11,13(17)-heptaene-11-carboxylic acid, Methyl aristolic acid, UNII-DYZ33R9ED7, CHEMBL520680, DTXCID60111126
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 54.0
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC2C(C1)CCC1CCC3CCCC3C12
Np Classifier Class Phenanthrenes
Deep Smiles COC=O)cccOCOc5cc9cccc6cccc6OC
Heavy Atom Count 23.0
Classyfire Class Phenanthrenes and derivatives
Scaffold Graph Node Level C1CCC2C(C1)CCC1CCC3OCOC3C12
Isotope Atom Count 0.0
Molecular Complexity 453.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Uniprot Id n.a.
Iupac Name methyl 8-methoxynaphtho[2,1-g][1,3]benzodioxole-5-carboxylate
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Benzenoids
Xlogp 4.1
Gsk 4 400 Rule True
Molecular Formula C18H14O5
Scaffold Graph Node Bond Level c1ccc2c(c1)ccc1ccc3c(c12)OCO3
Prediction Swissadme 0.0
Inchi Key LBBQPQFZUZOHTO-UHFFFAOYSA-N
Silicos It Class Moderately soluble
Fcsp3 0.1666666666666666
Logs -6.863
Rotatable Bond Count 3.0
Logd 3.838
Synonyms aristolic acid methyl ester
Esol Class Moderately soluble
Functional Groups c1cOCO1, cC(=O)OC, cOC
Compound Name Methyl Aristolate
Prediction Hob Swissadme 0.0
Exact Mass 310.084
Formal Charge 0.0
Monoisotopic Mass 310.084
Hydrogen Bond Acceptor Count 5.0
Molecular Weight 310.3
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 0.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -4.574125782608695
Inchi InChI=1S/C18H14O5/c1-20-14-5-3-4-11-10(14)6-7-12-13(18(19)21-2)8-15-17(16(11)12)23-9-22-15/h3-8H,9H2,1-2H3
Smiles COC1=CC=CC2=C1C=CC3=C2C4=C(C=C3C(=O)OC)OCO4
Nring 4.0
Np Classifier Biosynthetic Pathway Shikimates and Phenylpropanoids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Phenanthrenoids

  • 1. Outgoing r'ship FOUND_IN to/from Aristolochia Indica (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Aristolochia Manshuriensis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all