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18-Hydroxycamptothecin

PubChem CID: 159549

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Compound Synonyms 18-Hydroxycamptothecin, 116139-46-9, 1H-Pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione, 4-hydroxy-4-(2-hydroxyethyl)-, (S)-, DTXSID80921926, (19S)-19-Hydroxy-19-(2-hydroxyethyl)-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione, 4-Hydroxy-4-(2-hydroxyethyl)-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
Topological Polar Surface Area 100.0
Hydrogen Bond Donor Count 2.0
Heavy Atom Count 27.0
Isotope Atom Count 0.0
Molecular Complexity 759.0
Database Name cmaup_ingredients;pubchem
Defined Atom Stereocenter Count 1.0
Iupac Name (19S)-19-hydroxy-19-(2-hydroxyethyl)-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione
Prediction Hob 1.0
Xlogp 0.3
Molecular Formula C20H16N2O5
Prediction Swissadme 0.0
Inchi Key CCBXXGSAGQNXHX-FQEVSTJZSA-N
Fcsp3 0.25
Logs -3.925
Rotatable Bond Count 2.0
Logd 1.01
Compound Name 18-Hydroxycamptothecin
Prediction Hob Swissadme 0.0
Exact Mass 364.106
Formal Charge 0.0
Monoisotopic Mass 364.106
Hydrogen Bond Acceptor Count 6.0
Molecular Weight 364.4
Covalent Unit Count 1.0
Total Atom Stereocenter Count 1.0
Total Bond Stereocenter Count 0.0
Esol -3.671831918518519
Inchi InChI=1S/C20H16N2O5/c23-6-5-20(26)14-8-16-17-12(7-11-3-1-2-4-15(11)21-17)9-22(16)18(24)13(14)10-27-19(20)25/h1-4,7-8,23,26H,5-6,9-10H2/t20-/m0/s1
Smiles C1C2=CC3=CC=CC=C3N=C2C4=CC5=C(COC(=O)[C@@]5(CCO)O)C(=O)N41
Nring 5.0
Defined Bond Stereocenter Count 0.0