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17-O-Acetylajmaline

PubChem CID: 15942893

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Compound Synonyms 17-O-acetylajmaline, 21alpha-hydroxyajmalan-17alpha-yl acetate, CHEBI:37674, (1R,9R,10S,12R,13S,14R,16S,17S,18R)-13-Ethyl-14-hydroxy-8-methyl-8,15-diazahexacyclo(14.2.1.0,.0,.0,.0,)nonadeca-2,4,6-trien-18-yl acetic acid, (1R,9R,10S,12R,13S,14R,16S,17S,18R)-13-Ethyl-14-hydroxy-8-methyl-8,15-diazahexacyclo[14.2.1.0,.0,.0,.0,]nonadeca-2,4,6-trien-18-yl acetic acid, ((1R,9R,10S,12R,13S,14R,16S,18R)-13-ethyl-14-hydroxy-8-methyl-8,15-diazahexacyclo(14.2.1.01,9.02,7.010,15.012,17)nonadeca-2,4,6-trien-18-yl) acetate, [(1R,9R,10S,12R,13S,14R,16S,18R)-13-ethyl-14-hydroxy-8-methyl-8,15-diazahexacyclo[14.2.1.01,9.02,7.010,15.012,17]nonadeca-2,4,6-trien-18-yl] acetate, Q27117222, 19918-92-4
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 53.0
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC2C(C1)CC1C3CC4CCC3C3CC21CC43
Np Classifier Class Corynanthe type
Deep Smiles CC[C@@H][C@@H]O)N[C@@H]C[C@H]6C[C@H]6[C@H][C@@]C7OC=O)C))))C8)ccN5C))cccc6
Heavy Atom Count 27.0
Classyfire Class Ajmaline-sarpagine alkaloids
Scaffold Graph Node Level C1CCC2C(C1)NC1C3CC4CCN3C3CC21CC43
Isotope Atom Count 0.0
Molecular Complexity 670.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 8.0
Iupac Name [(1R,9R,10S,12R,13S,14R,16S,18R)-13-ethyl-14-hydroxy-8-methyl-8,15-diazahexacyclo[14.2.1.01,9.02,7.010,15.012,17]nonadeca-2,4,6-trien-18-yl] acetate
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 2.4
Gsk 4 400 Rule True
Molecular Formula C22H28N2O3
Scaffold Graph Node Bond Level c1ccc2c(c1)NC1C3CC4CCN3C3CC21CC43
Inchi Key SRISWFJLVRCABV-HUXZXPIYSA-N
Silicos It Class Soluble
Rotatable Bond Count 3.0
Synonyms 17-o-acetylajmaline
Esol Class Soluble
Functional Groups COC(C)=O, C[C@@H](O)N(C)C, cN(C)C
Compound Name 17-O-Acetylajmaline
Exact Mass 368.21
Formal Charge 0.0
Monoisotopic Mass 368.21
Hydrogen Bond Acceptor Count 5.0
Molecular Weight 368.5
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 9.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C22H28N2O3/c1-4-12-13-9-16-19-22(14-7-5-6-8-15(14)23(19)3)10-17(24(16)21(12)26)18(13)20(22)27-11(2)25/h5-8,12-13,16-21,26H,4,9-10H2,1-3H3/t12-,13-,16-,17-,18?,19-,20+,21+,22+/m0/s1
Smiles CC[C@H]1[C@@H]2C[C@H]3[C@H]4[C@@]5(C[C@@H](C2[C@H]5OC(=O)C)N3[C@@H]1O)C6=CC=CC=C6N4C
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Rauvolfia Serpentina (Plant) Rel Props:Reference:https://doi.org/10.1186/s12906-015-0683-7