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5H-Benzo(g)-1,3-benzodioxolo(6,5,4-de)quinolin-8-ol, 6,7,7a,8-tetrahydro-, (7aS-cis)-

PubChem CID: 158566

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Compound Synonyms noroliveroline, Noroliveroline, (-)-, 97CWM52SAJ, 83730-14-7, 5H-Benzo(g)-1,3-benzodioxolo(6,5,4-de)quinolin-8-ol, 6,7,7a,8-tetrahydro-, (7aS-cis)-, UNII-97CWM52SAJ, (-)-NOROLIVEROLINE, CHEMBL464657, DTXSID301003743, NSC782327, NSC-782327, NCGC00488809-01, Q15426993, (7aS,8S)-6,7,7a,8-Tetrahydro-2H,5H-benzo[g][1,3]benzodioxolo[6,5,4-de]quinolin-8-ol, 6,7,7a,8-Tetrahydro-2H,5H-[1,3]benzodioxolo[6,5,4-de]benzo[g]quinolin-8-ol, (12S,13S)-3,5-dioxa-11-azapentacyclo[10.7.1.02,6.08,20.014,19]icosa-1(20),2(6),7,14,16,18-hexaen-13-ol
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 50.7
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC2C(C1)CC1CCCC3CC4CCCC4C2C13
Np Classifier Class Aporphine alkaloids
Deep Smiles O[C@H]cccccc6-cc[C@@H]%10NCCc6ccc%10OCO5
Heavy Atom Count 21.0
Classyfire Class Aporphines
Scaffold Graph Node Level C1CCC2C(C1)CC1NCCC3CC4OCOC4C2C31
Classyfire Subclass Hydroxy-7-aporphines
Isotope Atom Count 0.0
Molecular Complexity 417.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 2.0
Iupac Name (12S,13S)-3,5-dioxa-11-azapentacyclo[10.7.1.02,6.08,20.014,19]icosa-1(20),2(6),7,14,16,18-hexaen-13-ol
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 1.7
Gsk 4 400 Rule True
Molecular Formula C17H15NO3
Scaffold Graph Node Bond Level c1ccc2c(c1)CC1NCCc3cc4c(c-2c31)OCO4
Prediction Swissadme 0.0
Inchi Key CKIYSMRPIBQTHQ-HOTGVXAUSA-N
Silicos It Class Moderately soluble
Fcsp3 0.2941176470588235
Rotatable Bond Count 0.0
Synonyms noroliveroline
Esol Class Soluble
Functional Groups CNC, CO, c1cOCO1
Compound Name 5H-Benzo(g)-1,3-benzodioxolo(6,5,4-de)quinolin-8-ol, 6,7,7a,8-tetrahydro-, (7aS-cis)-
Prediction Hob Swissadme 0.0
Exact Mass 281.105
Formal Charge 0.0
Monoisotopic Mass 281.105
Hydrogen Bond Acceptor Count 4.0
Molecular Weight 281.3
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 2.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -3.0905853428571426
Inchi InChI=1S/C17H15NO3/c19-16-11-4-2-1-3-10(11)14-13-9(5-6-18-15(13)16)7-12-17(14)21-8-20-12/h1-4,7,15-16,18-19H,5-6,8H2/t15-,16-/m0/s1
Smiles C1CN[C@@H]2[C@H](C3=CC=CC=C3C4=C2C1=CC5=C4OCO5)O
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tyrosine alkaloids