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Sapintoxin B

PubChem CID: 157762

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Compound Synonyms sapintoxin B, 81345-29-1, Benzoic acid, 2-(methylamino)-, (1aR,1bS,4S,4aR,7aR,7bR,8R,9R,9aS)-9a-(acetyloxy)-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-4,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1H-cyclopropa(3,4)benz(1,2-e)azulen-9-yl ester, DTXSID90231063, (1R,2S,6R,7S,10S,11R,13S,14R,15R)-13-(Acetyloxy)-1,7-dihydroxy-8-(hydroxymethyl)-4,12,12,15-tetramethyl-5-oxotetracyclo(8.5.0.0,.0,)pentadeca-3,8-dien-14-yl 2-(methylamino)benzoic acid, (1R,2S,6R,7S,10S,11R,13S,14R,15R)-13-(Acetyloxy)-1,7-dihydroxy-8-(hydroxymethyl)-4,12,12,15-tetramethyl-5-oxotetracyclo[8.5.0.0,.0,]pentadeca-3,8-dien-14-yl 2-(methylamino)benzoic acid, CHEMBL504966, DTXCID90153554
Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 142.0
Hydrogen Bond Donor Count 4.0
Pfizer 3 75 Rule True
Scaffold Graph Level CC(CC1CC2C3CCC(C)C3CCCC2C2CC12)C1CCCCC1
Np Classifier Class Tetracyclic diterpenoids, Tigliane diterpenoids
Deep Smiles OCC=C[C@H][C@@H]C[C@]3OC=O)C)))[C@@H][C@H][C@@]7[C@H][C@H][C@@H]%12O))C=O)C=C5)C)))))O))C))OC=O)cccccc6NC))))))))))))C)C
Heavy Atom Count 39.0
Classyfire Class Prenol lipids
Scaffold Graph Node Level OC1CCC2C1CCCC1C3CC3C(OC(O)C3CCCCC3)CC21
Classyfire Subclass Diterpenoids
Isotope Atom Count 0.0
Molecular Complexity 1130.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 9.0
Iupac Name [(1R,2R,6R,7S,10S,11R,13S,14R,15R)-13-acetyloxy-1,7-dihydroxy-8-(hydroxymethyl)-4,12,12,15-tetramethyl-5-oxo-14-tetracyclo[8.5.0.02,6.011,13]pentadeca-3,8-dienyl] 2-(methylamino)benzoate
Prediction Hob 0.0
Veber Rule False
Classyfire Superclass Lipids and lipid-like molecules
Xlogp 2.7
Gsk 4 400 Rule False
Molecular Formula C30H37NO8
Scaffold Graph Node Bond Level O=C(OC1CC2C3C=CC(=O)C3CC=CC2C2CC12)c1ccccc1
Prediction Swissadme 0.0
Inchi Key CUWDQBAYWDKQOB-WUTJDDJVSA-N
Silicos It Class Moderately soluble
Fcsp3 0.5666666666666667
Logs -4.235
Rotatable Bond Count 7.0
Logd 1.911
Synonyms sapintoxin b
Esol Class Moderately soluble
Functional Groups CC(=O)OC, CC(C)=CC, CC1=CCCC1=O, CO, cC(=O)OC, cNC
Compound Name Sapintoxin B
Prediction Hob Swissadme 0.0
Exact Mass 539.252
Formal Charge 0.0
Monoisotopic Mass 539.252
Hydrogen Bond Acceptor Count 9.0
Molecular Weight 539.6
Gi Absorption False
Covalent Unit Count 1.0
Total Atom Stereocenter Count 9.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -4.538521153846156
Inchi InChI=1S/C30H37NO8/c1-14-11-19-22(23(14)34)24(35)17(13-32)12-20-25-28(4,5)30(25,39-16(3)33)26(15(2)29(19,20)37)38-27(36)18-9-7-8-10-21(18)31-6/h7-12,15,19-20,22,24-26,31-32,35,37H,13H2,1-6H3/t15-,19-,20+,22+,24-,25-,26-,29+,30-/m1/s1
Smiles C[C@@H]1[C@H]([C@@]2([C@@H](C2(C)C)[C@H]3[C@]1([C@@H]4C=C(C(=O)[C@H]4[C@@H](C(=C3)CO)O)C)O)OC(=O)C)OC(=O)C5=CC=CC=C5NC
Nring 5.0
Np Classifier Biosynthetic Pathway Terpenoids
Defined Bond Stereocenter Count 0.0
Egan Rule False
Np Classifier Superclass Diterpenoids

  • 1. Outgoing r'ship FOUND_IN to/from Sapium Indicum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Shirakiopsis Indica (Plant) Rel Props:Reference:ISBN:9788185042114