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Angustone A

PubChem CID: 15664151

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Compound Synonyms Angustone A, 2'-Hydroxylupalbigenin, 5,7,2',4'-Tetrahydroxy-6,3'-diprenylisoflavone, 90686-13-8, CHEMBL3808919, SCHEMBL24074923, BDBM50172094, LMPK12050291, 3-[2,4-dihydroxy-3-(3-methylbut-2-enyl)phenyl]-5,7-dihydroxy-6-(3-methylbut-2-enyl)chromen-4-one
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 107.0
Hydrogen Bond Donor Count 4.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1C2CCCCC2CCC1C1CCCCC1
Np Classifier Class Isoflavones
Deep Smiles CC=CCccO)cccc6O))ccoccc6=O))cO)ccc6)O))CC=CC)C))))))))))))))))))C
Heavy Atom Count 31.0
Classyfire Class Isoflavonoids
Scaffold Graph Node Level OC1C(C2CCCCC2)COC2CCCCC21
Classyfire Subclass Isoflavans
Isotope Atom Count 0.0
Molecular Complexity 745.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Uniprot Id P18031, P22303, Q16236
Iupac Name 3-[2,4-dihydroxy-3-(3-methylbut-2-enyl)phenyl]-5,7-dihydroxy-6-(3-methylbut-2-enyl)chromen-4-one
Prediction Hob 0.0
Veber Rule True
Classyfire Superclass Phenylpropanoids and polyketides
Target Id NPT178
Xlogp 6.2
Gsk 4 400 Rule False
Molecular Formula C25H26O6
Scaffold Graph Node Bond Level O=c1c(-c2ccccc2)coc2ccccc12
Prediction Swissadme 0.0
Inchi Key KKFAKKIIFUFASS-UHFFFAOYSA-N
Silicos It Class Poorly soluble
Fcsp3 0.24
Logs -2.833
Rotatable Bond Count 5.0
Logd 2.844
Synonyms 2'-hydroxylupalbigenin, angustone a
Esol Class Poorly soluble
Functional Groups CC=C(C)C, c=O, cO, coc
Compound Name Angustone A
Prediction Hob Swissadme 0.0
Exact Mass 422.173
Formal Charge 0.0
Monoisotopic Mass 422.173
Hydrogen Bond Acceptor Count 6.0
Molecular Weight 422.5
Gi Absorption False
Covalent Unit Count 1.0
Total Atom Stereocenter Count 0.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -5.894392883870968
Inchi InChI=1S/C25H26O6/c1-13(2)5-7-16-19(26)10-9-15(23(16)28)18-12-31-21-11-20(27)17(8-6-14(3)4)24(29)22(21)25(18)30/h5-6,9-12,26-29H,7-8H2,1-4H3
Smiles CC(=CCC1=C(C=CC(=C1O)C2=COC3=C(C2=O)C(=C(C(=C3)O)CC=C(C)C)O)O)C
Nring 3.0
Np Classifier Biosynthetic Pathway Shikimates and Phenylpropanoids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Isoflavonoids

  • 1. Outgoing r'ship FOUND_IN to/from Glycyrrhiza Glabra (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Glycyrrhiza Inflata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Glycyrrhiza Uralensis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 4. Outgoing r'ship FOUND_IN to/from Lupinus Albus (Plant) Rel Props:Reference:https://doi.org/10.2174/0929867033456729
  • 5. Outgoing r'ship FOUND_IN to/from Lupinus Angustifolius (Plant) Rel Props:Reference:https://doi.org/10.2174/0929867033456729
  • 6. Outgoing r'ship FOUND_IN to/from Polygonum Salicifolium (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all