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methyl (1R,9S,10S,12R,14S,15S,20R)-14-ethyl-6-[(1S,12S,14R,15E,18S)-15-ethylidene-18-(hydroxymethyl)-18-methoxycarbonyl-17-methyl-10,17-diazatetracyclo[12.3.1.03,11.04,9]octadeca-3(11),4,6,8-tetraen-12-yl]-5,9-dimethoxy-19-oxa-8,16-diazahexacyclo[10.6.2.01,9.02,7.010,15.016,20]icosa-2(7),3,5-triene-10-carboxylate

PubChem CID: 156017653

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Compound Synonyms CHEMBL4644457
Topological Polar Surface Area 135.0
Hydrogen Bond Donor Count 3.0
Heavy Atom Count 57.0
Isotope Atom Count 0.0
Molecular Complexity 1650.0
Database Name cmaup_ingredients;pubchem
Defined Atom Stereocenter Count 11.0
Iupac Name methyl (1R,9S,10S,12R,14S,15S,20R)-14-ethyl-6-[(1S,12S,14R,15E,18S)-15-ethylidene-18-(hydroxymethyl)-18-methoxycarbonyl-17-methyl-10,17-diazatetracyclo[12.3.1.03,11.04,9]octadeca-3(11),4,6,8-tetraen-12-yl]-5,9-dimethoxy-19-oxa-8,16-diazahexacyclo[10.6.2.01,9.02,7.010,15.016,20]icosa-2(7),3,5-triene-10-carboxylate
Prediction Hob 0.0
Xlogp 4.2
Molecular Formula C45H56N4O8
Prediction Swissadme 0.0
Inchi Key ZBUDHFHPEOYQJQ-BGVGJJQOSA-N
Fcsp3 0.6
Logs -4.189
Rotatable Bond Count 9.0
Logd 4.387
Compound Name methyl (1R,9S,10S,12R,14S,15S,20R)-14-ethyl-6-[(1S,12S,14R,15E,18S)-15-ethylidene-18-(hydroxymethyl)-18-methoxycarbonyl-17-methyl-10,17-diazatetracyclo[12.3.1.03,11.04,9]octadeca-3(11),4,6,8-tetraen-12-yl]-5,9-dimethoxy-19-oxa-8,16-diazahexacyclo[10.6.2.01,9.02,7.010,15.016,20]icosa-2(7),3,5-triene-10-carboxylate
Prediction Hob Swissadme 0.0
Exact Mass 780.41
Formal Charge 0.0
Monoisotopic Mass 780.41
Hydrogen Bond Acceptor Count 11.0
Molecular Weight 780.9
Covalent Unit Count 1.0
Total Atom Stereocenter Count 11.0
Total Bond Stereocenter Count 1.0
Esol -6.935007442105263
Inchi InChI=1S/C45H56N4O8/c1-8-24-18-26-21-43(41(52)55-6)38(24)49-17-16-44(57-39(26)49)30-14-15-33(53-4)35(37(30)47-45(43,44)56-7)29-19-31-25(9-2)22-48(3)34(42(31,23-50)40(51)54-5)20-28-27-12-10-11-13-32(27)46-36(28)29/h9-15,24,26,29,31,34,38-39,46-47,50H,8,16-23H2,1-7H3/b25-9-/t24-,26+,29-,31+,34-,38-,39+,42-,43+,44+,45-/m0/s1
Smiles CC[C@H]1C[C@@H]2C[C@@]3([C@H]1N4[C@@H]2O[C@]5([C@@]3(NC6=C5C=CC(=C6[C@@H]7C[C@@H]8/C(=C\C)/CN([C@H]([C@@]8(CO)C(=O)OC)CC9=C7NC1=CC=CC=C91)C)OC)OC)CC4)C(=O)OC
Nring 13.0
Defined Bond Stereocenter Count 1.0