3H-Bis(1)benzopyrano(3,4-b:6',5'-e)pyran-7(7aH)-one, 13,13a-dihydro-6,7a-dihydroxy-9,10-dimethoxy-3,3-dimethyl-, (7aR-cis)-
PubChem CID: 155725
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| Compound Synonyms | 11-Hydroxytephrosin, 72458-85-6, 3H-Bis(1)benzopyrano(3,4-b:6',5'-e)pyran-7(7aH)-one, 13,13a-dihydro-6,7a-dihydroxy-9,10-dimethoxy-3,3-dimethyl-, (7aR-cis)-, DTXSID50222755, (1R,14R)-11,14-dihydroxy-17,18-dimethoxy-7,7-dimethyl-2,8,21-trioxapentacyclo[12.8.0.03,12.04,9.015,20]docosa-3(12),4(9),5,10,15,17,19-heptaen-13-one, CHEMBL419669, DTXCID80145246, HY-N1022, AKOS032948932, FS-9513, NCGC00385215-01!, CS-0016258 |
|---|---|
| Ghose Rule | True |
| Classyfire Kingdom | Organic compounds |
| Topological Polar Surface Area | 104.0 |
| Hydrogen Bond Donor Count | 2.0 |
| Pfizer 3 75 Rule | True |
| Scaffold Graph Level | CC1C2CCC3CCCCC3C2CC2CCC3CCCCC3C21 |
| Np Classifier Class | Rotenoids |
| Deep Smiles | COcccOC[C@@H][C@@]c6cc%10OC)))))O)C=O)ccO6)cC=CCOc6cc%10O)))))C)C |
| Heavy Atom Count | 31.0 |
| Classyfire Class | Isoflavonoids |
| Scaffold Graph Node Level | OC1C2CCC3OCCCC3C2OC2COC3CCCCC3C21 |
| Classyfire Subclass | Rotenoids |
| Isotope Atom Count | 0.0 |
| Molecular Complexity | 752.0 |
| Database Name | cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem |
| Defined Atom Stereocenter Count | 2.0 |
| Uniprot Id | P47199 |
| Iupac Name | (1R,14R)-11,14-dihydroxy-17,18-dimethoxy-7,7-dimethyl-2,8,21-trioxapentacyclo[12.8.0.03,12.04,9.015,20]docosa-3(12),4(9),5,10,15,17,19-heptaen-13-one |
| Prediction Hob | 1.0 |
| Veber Rule | True |
| Classyfire Superclass | Phenylpropanoids and polyketides |
| Xlogp | 3.2 |
| Gsk 4 400 Rule | False |
| Molecular Formula | C23H22O8 |
| Scaffold Graph Node Bond Level | O=C1c2ccc3c(c2OC2COc4ccccc4C12)C=CCO3 |
| Prediction Swissadme | 1.0 |
| Inchi Key | OFLCPNIRDVOOEZ-WZONZLPQSA-N |
| Silicos It Class | Moderately soluble |
| Fcsp3 | 0.3478260869565217 |
| Logs | -4.247 |
| Rotatable Bond Count | 2.0 |
| Logd | 3.699 |
| Synonyms | 11-hydroxytephrosin, 12a-hydroxy-α-toxicarol |
| Esol Class | Moderately soluble |
| Functional Groups | CO, cC(C)=O, cC=CC, cO, cOC |
| Compound Name | 3H-Bis(1)benzopyrano(3,4-b:6',5'-e)pyran-7(7aH)-one, 13,13a-dihydro-6,7a-dihydroxy-9,10-dimethoxy-3,3-dimethyl-, (7aR-cis)- |
| Prediction Hob Swissadme | 1.0 |
| Exact Mass | 426.131 |
| Formal Charge | 0.0 |
| Monoisotopic Mass | 426.131 |
| Hydrogen Bond Acceptor Count | 8.0 |
| Molecular Weight | 426.4 |
| Gi Absorption | True |
| Covalent Unit Count | 1.0 |
| Total Atom Stereocenter Count | 2.0 |
| Total Bond Stereocenter Count | 0.0 |
| Lipinski Rule Of 5 | True |
| Esol | -4.641661812903227 |
| Inchi | InChI=1S/C23H22O8/c1-22(2)6-5-11-14(31-22)8-13(24)19-20(11)30-18-10-29-15-9-17(28-4)16(27-3)7-12(15)23(18,26)21(19)25/h5-9,18,24,26H,10H2,1-4H3/t18-,23-/m1/s1 |
| Smiles | CC1(C=CC2=C(O1)C=C(C3=C2O[C@@H]4COC5=CC(=C(C=C5[C@@]4(C3=O)O)OC)OC)O)C |
| Nring | 5.0 |
| Np Classifier Biosynthetic Pathway | Shikimates and Phenylpropanoids |
| Defined Bond Stereocenter Count | 0.0 |
| Egan Rule | True |
| Np Classifier Superclass | Isoflavonoids |
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FOUND_INto/from Pedicularis Densispica (Plant) Rel Props:Reference: - 198. Outgoing r'ship
FOUND_INto/from Pedicularis Hoffmeister (Plant) Rel Props:Reference: - 199. Outgoing r'ship
FOUND_INto/from Pedicularis Longiflora (Plant) Rel Props:Reference: - 200. Outgoing r'ship
FOUND_INto/from Pedicularis Megalantha (Plant) Rel Props:Reference: - 201. Outgoing r'ship
FOUND_INto/from Pedicularis Mollis (Plant) Rel Props:Reference: - 202. Outgoing r'ship
FOUND_INto/from Pedicularis Muscicola (Plant) Rel Props:Reference: - 203. Outgoing r'ship
FOUND_INto/from Pedicularis Oederi (Plant) Rel Props:Reference: - 204. Outgoing r'ship
FOUND_INto/from Pedicularis Pectinata (Plant) Rel Props:Reference: - 205. Outgoing r'ship
FOUND_INto/from Pedicularis Plicata (Plant) Rel Props:Reference: - 206. Outgoing r'ship
FOUND_INto/from Pedicularis Procera (Plant) Rel Props:Reference: - 207. Outgoing r'ship
FOUND_INto/from Pedicularis Punctata (Plant) Rel Props:Reference: - 208. Outgoing r'ship
FOUND_INto/from Pedicularis Rex (Plant) Rel Props:Reference: - 209. Outgoing r'ship
FOUND_INto/from Pedicularis Semitorta (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all - 210. Outgoing r'ship
FOUND_INto/from Pedicularis Striata (Plant) Rel Props:Reference: - 211. Outgoing r'ship
FOUND_INto/from Persea Americana (Plant) Rel Props:Reference: - 212. Outgoing r'ship
FOUND_INto/from Phytolacca Americana (Plant) Rel Props:Reference: - 213. Outgoing r'ship
FOUND_INto/from Pieris Japonica (Plant) Rel Props:Reference: - 214. Outgoing r'ship
FOUND_INto/from Plagiochila Acanthophylla (Plant) Rel Props:Reference: - 215. Outgoing r'ship
FOUND_INto/from Polygala Fruticosa (Plant) Rel Props:Reference: - 216. Outgoing r'ship
FOUND_INto/from Polyscias Fruticosa (Plant) Rel Props:Reference: - 217. Outgoing r'ship
FOUND_INto/from Prunus Japonica (Plant) Rel Props:Reference: - 218. Outgoing r'ship
FOUND_INto/from Pseudotsuga Japonica (Plant) Rel Props:Reference: - 219. Outgoing r'ship
FOUND_INto/from Pteris Cretica (Plant) Rel Props:Reference: - 220. Outgoing r'ship
FOUND_INto/from Pteris Japonica (Plant) Rel Props:Reference: - 221. Outgoing r'ship
FOUND_INto/from Pueraria Montana (Plant) Rel Props:Reference: - 222. Outgoing r'ship
FOUND_INto/from Pyrola Japonica (Plant) Rel Props:Reference: - 223. Outgoing r'ship
FOUND_INto/from Ranzania Japonica (Plant) Rel Props:Reference: - 224. Outgoing r'ship
FOUND_INto/from Rhamnus Japonica (Plant) Rel Props:Reference: - 225. Outgoing r'ship
FOUND_INto/from Rohdea Japonica (Plant) Rel Props:Reference: - 226. Outgoing r'ship
FOUND_INto/from Ruta Montana (Plant) Rel Props:Reference: - 227. Outgoing r'ship
FOUND_INto/from Sabia Japonica (Plant) Rel Props:Reference: - 228. Outgoing r'ship
FOUND_INto/from Sagina Japonica (Plant) Rel Props:Reference: - 229. Outgoing r'ship
FOUND_INto/from Salacia Fruticosa (Plant) Rel Props:Reference: - 230. Outgoing r'ship
FOUND_INto/from Salix Japonica (Plant) Rel Props:Reference: - 231. Outgoing r'ship
FOUND_INto/from Satureja Montana (Plant) Rel Props:Reference: - 232. Outgoing r'ship
FOUND_INto/from Saussurea Japonica (Plant) Rel Props:Reference: - 233. Outgoing r'ship
FOUND_INto/from Scopolia Atropoides (Plant) Rel Props:Reference: - 234. Outgoing r'ship
FOUND_INto/from Scopolia Carniolica (Plant) Rel Props:Reference: - 235. Outgoing r'ship
FOUND_INto/from Scopolia Hladnikiana (Plant) Rel Props:Reference: - 236. Outgoing r'ship
FOUND_INto/from Scopolia Japonica (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all - 237. Outgoing r'ship
FOUND_INto/from Scopolia Parviflora (Plant) Rel Props:Reference: - 238. Outgoing r'ship
FOUND_INto/from Scopolia Sinensis (Plant) Rel Props:Reference: - 239. Outgoing r'ship
FOUND_INto/from Scopolia Tangutica (Plant) Rel Props:Reference: - 240. Outgoing r'ship
FOUND_INto/from Senna Montana (Plant) Rel Props:Reference: - 241. Outgoing r'ship
FOUND_INto/from Skimmia Japonica (Plant) Rel Props:Reference: - 242. Outgoing r'ship
FOUND_INto/from Sophora Japonica (Plant) Rel Props:Reference: - 243. Outgoing r'ship
FOUND_INto/from Spergula Japonica (Plant) Rel Props:Reference: - 244. Outgoing r'ship
FOUND_INto/from Spiraea Japonica (Plant) Rel Props:Reference: - 245. Outgoing r'ship
FOUND_INto/from Staehelina Fruticosa (Plant) Rel Props:Reference: - 246. Outgoing r'ship
FOUND_INto/from Stemona Japonica (Plant) Rel Props:Reference: - 247. Outgoing r'ship
FOUND_INto/from Stephania Japonica (Plant) Rel Props:Reference: - 248. Outgoing r'ship
FOUND_INto/from Stizophyllum Riparium (Plant) Rel Props:Reference: - 249. Outgoing r'ship
FOUND_INto/from Stylosanthes Fruticosa (Plant) Rel Props:Reference: - 250. Outgoing r'ship
FOUND_INto/from Suaeda Fruticosa (Plant) Rel Props:Reference: - 251. Outgoing r'ship
FOUND_INto/from Swertia Japonica (Plant) Rel Props:Reference: - 252. Outgoing r'ship
FOUND_INto/from Tephrosia Villosa (Plant) Rel Props:Reference:ISBN:9788172363093 - 253. Outgoing r'ship
FOUND_INto/from Ternstroemia Japonica (Plant) Rel Props:Reference: - 254. Outgoing r'ship
FOUND_INto/from Tilia Japonica (Plant) Rel Props:Reference: - 255. Outgoing r'ship
FOUND_INto/from Torilis Japonica (Plant) Rel Props:Reference: - 256. Outgoing r'ship
FOUND_INto/from Trapa Japonica (Plant) Rel Props:Reference: - 257. Outgoing r'ship
FOUND_INto/from Trifolium Fruticosa (Plant) Rel Props:Reference: - 258. Outgoing r'ship
FOUND_INto/from Ulmus Americana (Plant) Rel Props:Reference: - 259. Outgoing r'ship
FOUND_INto/from Vernicia Montana (Plant) Rel Props:Reference: - 260. Outgoing r'ship
FOUND_INto/from Waltheria Americana (Plant) Rel Props:Reference: - 261. Outgoing r'ship
FOUND_INto/from Woodfordia Fruticosa (Plant) Rel Props:Reference: - 262. Outgoing r'ship
FOUND_INto/from Xanthium Riparium (Plant) Rel Props:Reference: - 263. Outgoing r'ship
FOUND_INto/from Ximenia Americana (Plant) Rel Props:Reference: - 264. Outgoing r'ship
FOUND_INto/from Youngia Japonica (Plant) Rel Props:Reference: