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(1S,4S,7R,8S,11R,12R,13S)-7-hydroxy-2,12-dimethyl-13-propan-2-yl-10-oxa-2-azatetracyclo[5.4.1.18,11.04,12]tridecan-9-one

PubChem CID: 15558887

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Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 49.8
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1CC2CC1C1CCC3CCC2C31
Np Classifier Class Picrotoxane sesquiterpenoids, Terpenoid alkaloids
Deep Smiles CC[C@@H][C@H]OC=O)[C@@H]5[C@][C@][C@@H]7NC)C[C@H]5CC8))))))C))O)))))))C
Heavy Atom Count 20.0
Classyfire Class Indoles and derivatives
Scaffold Graph Node Level OC1OC2CC1C1CCC3CNC2C31
Isotope Atom Count 0.0
Molecular Complexity 478.0
Database Name cmaup_ingredients;imppat_phytochem;pubchem
Defined Atom Stereocenter Count 7.0
Iupac Name (1S,4S,7R,8S,11R,12R,13S)-7-hydroxy-2,12-dimethyl-13-propan-2-yl-10-oxa-2-azatetracyclo[5.4.1.18,11.04,12]tridecan-9-one
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Organoheterocyclic compounds
Xlogp 1.8
Gsk 4 400 Rule True
Molecular Formula C16H25NO3
Scaffold Graph Node Bond Level O=C1OC2CC1C1CCC3CNC2C31
Prediction Swissadme 1.0
Inchi Key QSNCUGULHPBRGR-FYPZSMAZSA-N
Silicos It Class Soluble
Fcsp3 0.9375
Logs -3.686
Rotatable Bond Count 1.0
Logd 3.484
Synonyms 6-hydroxydendrobine, dendramine
Esol Class Soluble
Functional Groups CC(=O)OC, CN(C)C, CO
Compound Name (1S,4S,7R,8S,11R,12R,13S)-7-hydroxy-2,12-dimethyl-13-propan-2-yl-10-oxa-2-azatetracyclo[5.4.1.18,11.04,12]tridecan-9-one
Prediction Hob Swissadme 1.0
Exact Mass 279.183
Formal Charge 0.0
Monoisotopic Mass 279.183
Hydrogen Bond Acceptor Count 4.0
Molecular Weight 279.37
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 7.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -2.6212055999999997
Inchi InChI=1S/C16H25NO3/c1-8(2)10-11-14(18)20-12(10)13-15(3)9(7-17(13)4)5-6-16(11,15)19/h8-13,19H,5-7H2,1-4H3/t9-,10+,11-,12-,13-,15-,16-/m1/s1
Smiles CC(C)[C@@H]1[C@@H]2[C@@H]3[C@]4([C@H](CC[C@]4([C@H]1C(=O)O2)O)CN3C)C
Nring 8.0
Np Classifier Biosynthetic Pathway Alkaloids, Terpenoids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Pseudoalkaloids, Sesquiterpenoids

  • 1. Outgoing r'ship FOUND_IN to/from Corydalis Conspersa (Plant) Rel Props:Source_db:cmaup_ingredients
  • 2. Outgoing r'ship FOUND_IN to/from Dendrobium Nobile (Plant) Rel Props:Source_db:cmaup_ingredients
  • 3. Outgoing r'ship FOUND_IN to/from Gynochthodes Parvifolia (Plant) Rel Props:Source_db:cmaup_ingredients
  • 4. Outgoing r'ship FOUND_IN to/from Ligustrum Ovalifolium (Plant) Rel Props:Source_db:cmaup_ingredients
  • 5. Outgoing r'ship FOUND_IN to/from Mespilus Germanica (Plant) Rel Props:Source_db:cmaup_ingredients
  • 6. Outgoing r'ship FOUND_IN to/from Mikania Luetzelburgii (Plant) Rel Props:Source_db:cmaup_ingredients
  • 7. Outgoing r'ship FOUND_IN to/from Pittosporum Brevicalyx (Plant) Rel Props:Source_db:cmaup_ingredients
  • 8. Outgoing r'ship FOUND_IN to/from Sideritis Grandiflora (Plant) Rel Props:Source_db:cmaup_ingredients
  • 9. Outgoing r'ship FOUND_IN to/from Solanum Euacanthum (Plant) Rel Props:Source_db:cmaup_ingredients
  • 10. Outgoing r'ship FOUND_IN to/from Ungernia Victoris (Plant) Rel Props:Source_db:cmaup_ingredients