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N-[(20S)-3alpha-(Dimethylamino)pregn-5-en-20-yl]-N-methylacetamide

PubChem CID: 15558625

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Compound Synonyms 15437-93-1, N-[(20S)-3alpha-(Dimethylamino)pregn-5-en-20-yl]-N-methylacetamide, N-[(1S)-1-[(3R,8S,9S,10R,13S,14S,17S)-3-(dimethylamino)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethyl]-N-methylacetamide
Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 23.6
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC2C(C1)CCC1C3CCCC3CCC21
Np Classifier Class Pregnane steroids, Steroidal alkaloids
Deep Smiles CN[C@H][C@H]CC[C@@H][C@]5C)CC[C@H][C@H]6CC=C[C@]6C)CC[C@H]C6)NC)C))))))))))))))))))C))C=O)C
Heavy Atom Count 29.0
Classyfire Class Steroids and steroid derivatives
Scaffold Graph Node Level C1CCC2C(C1)CCC1C3CCCC3CCC21
Classyfire Subclass Azasteroids and derivatives
Isotope Atom Count 0.0
Molecular Complexity 684.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 8.0
Iupac Name N-[(1S)-1-[(3R,8S,9S,10R,13S,14S,17S)-3-(dimethylamino)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethyl]-N-methylacetamide
Prediction Hob 0.0
Veber Rule True
Classyfire Superclass Lipids and lipid-like molecules
Xlogp 5.3
Gsk 4 400 Rule False
Molecular Formula C26H44N2O
Scaffold Graph Node Bond Level C1=C2CCCCC2C2CCC3CCCC3C2C1
Prediction Swissadme 0.0
Inchi Key DNVZSDMHLPWULM-AHMRFOPESA-N
Silicos It Class Moderately soluble
Fcsp3 0.8846153846153846
Logs -3.928
Rotatable Bond Count 3.0
Logd 3.801
Synonyms saracocine
Esol Class Moderately soluble
Functional Groups CC(=O)N(C)C, CC=C(C)C, CN(C)C
Compound Name N-[(20S)-3alpha-(Dimethylamino)pregn-5-en-20-yl]-N-methylacetamide
Prediction Hob Swissadme 0.0
Exact Mass 400.345
Formal Charge 0.0
Monoisotopic Mass 400.345
Hydrogen Bond Acceptor Count 2.0
Molecular Weight 400.6
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 8.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -5.3738362
Inchi InChI=1S/C26H44N2O/c1-17(28(7)18(2)29)22-10-11-23-21-9-8-19-16-20(27(5)6)12-14-25(19,3)24(21)13-15-26(22,23)4/h8,17,20-24H,9-16H2,1-7H3/t17-,20+,21-,22+,23-,24-,25-,26+/m0/s1
Smiles C[C@@H]([C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@H](C4)N(C)C)C)C)N(C)C(=O)C
Nring 4.0
Np Classifier Biosynthetic Pathway Alkaloids, Terpenoids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Steroids, Pseudoalkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Sarcococca Pruniformis (Plant) Rel Props:Reference:ISBN:9788185042053
  • 2. Outgoing r'ship FOUND_IN to/from Sarcococca Saligna (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all