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methyl (1S,12R,14S,15E,18S)-15-ethylidene-12-[(1R,15R,17S,18R)-17-[(1R)-1-hydroxyethyl]-7-methoxy-3,13-diazapentacyclo[13.3.1.02,10.04,9.013,18]nonadeca-2(10),4,6,8-tetraen-6-yl]-17-methyl-10,17-diazatetracyclo[12.3.1.03,11.04,9]octadeca-3(11),4,6,8-tetraene-18-carboxylate

PubChem CID: 155556647

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Compound Synonyms CHEMBL4552573
Topological Polar Surface Area 93.8
Hydrogen Bond Donor Count 3.0
Heavy Atom Count 49.0
Isotope Atom Count 0.0
Molecular Complexity 1280.0
Database Name cmaup_ingredients;pubchem
Defined Atom Stereocenter Count 9.0
Iupac Name methyl (1S,12R,14S,15E,18S)-15-ethylidene-12-[(1R,15R,17S,18R)-17-[(1R)-1-hydroxyethyl]-7-methoxy-3,13-diazapentacyclo[13.3.1.02,10.04,9.013,18]nonadeca-2(10),4,6,8-tetraen-6-yl]-17-methyl-10,17-diazatetracyclo[12.3.1.03,11.04,9]octadeca-3(11),4,6,8-tetraene-18-carboxylate
Prediction Hob 0.0
Xlogp 5.3
Molecular Formula C41H50N4O4
Prediction Swissadme 0.0
Inchi Key JMXUXQRQFVSOOZ-JDGGXBFRSA-N
Fcsp3 0.5365853658536586
Logs -4.61
Rotatable Bond Count 5.0
Logd 4.533
Compound Name methyl (1S,12R,14S,15E,18S)-15-ethylidene-12-[(1R,15R,17S,18R)-17-[(1R)-1-hydroxyethyl]-7-methoxy-3,13-diazapentacyclo[13.3.1.02,10.04,9.013,18]nonadeca-2(10),4,6,8-tetraen-6-yl]-17-methyl-10,17-diazatetracyclo[12.3.1.03,11.04,9]octadeca-3(11),4,6,8-tetraene-18-carboxylate
Prediction Hob Swissadme 0.0
Exact Mass 662.383
Formal Charge 0.0
Monoisotopic Mass 662.383
Hydrogen Bond Acceptor Count 6.0
Molecular Weight 662.9
Covalent Unit Count 1.0
Total Atom Stereocenter Count 9.0
Total Bond Stereocenter Count 1.0
Esol -7.249561734693879
Inchi InChI=1S/C41H50N4O4/c1-6-23-20-44(3)35-17-31-24-9-7-8-10-33(24)42-39(31)30(15-27(23)37(35)41(47)49-5)29-16-34-28(18-36(29)48-4)25-11-12-45-19-22-13-26(21(2)46)40(45)32(14-22)38(25)43-34/h6-10,16,18,21-22,26-27,30,32,35,37,40,42-43,46H,11-15,17,19-20H2,1-5H3/b23-6-/t21-,22+,26-,27-,30-,32+,35+,37+,40+/m1/s1
Smiles C/C=C\1/CN([C@H]2CC3=C([C@H](C[C@H]1[C@@H]2C(=O)OC)C4=C(C=C5C6=C([C@@H]7C[C@@H]8C[C@@H]([C@@H]7N(C8)CC6)[C@@H](C)O)NC5=C4)OC)NC9=CC=CC=C39)C
Nring 10.0
Defined Bond Stereocenter Count 1.0