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Cathaformine

PubChem CID: 15462433

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Compound Synonyms cathaformine, methyl (12S)-16-hydroxy-7,17-dimethoxy-3,5-dioxa-11-azapentacyclo(10.7.1.02,6.08,20.014,19)icosa-1,6,8(20),14,16,18-hexaene-11-carboxylate, methyl (12S)-16-hydroxy-7,17-dimethoxy-3,5-dioxa-11-azapentacyclo[10.7.1.02,6.08,20.014,19]icosa-1,6,8(20),14,16,18-hexaene-11-carboxylate, CHEMBL517848, 196099-32-8
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 86.7
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC2C(C1)CC1CCCC3CC4CCCC4C2C13
Np Classifier Class Aporphine alkaloids, Isoquinoline alkaloids
Deep Smiles COC=O)NCCcc[C@@H]6CcccO)ccc6-c%10ccc%14OC)))OCO5))))))))OC
Heavy Atom Count 29.0
Classyfire Class Aporphines
Scaffold Graph Node Level C1CCC2C(C1)CC1NCCC3CC4OCOC4C2C31
Isotope Atom Count 0.0
Molecular Complexity 632.0
Database Name imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 1.0
Uniprot Id n.a.
Iupac Name methyl (12S)-16-hydroxy-7,17-dimethoxy-3,5-dioxa-11-azapentacyclo[10.7.1.02,6.08,20.014,19]icosa-1,6,8(20),14,16,18-hexaene-11-carboxylate
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 2.8
Gsk 4 400 Rule True
Molecular Formula C21H21NO7
Scaffold Graph Node Bond Level c1ccc2c(c1)CC1NCCc3cc4c(c-2c31)OCO4
Inchi Key KVWMKVVFUVBYJR-ZDUSSCGKSA-N
Silicos It Class Moderately soluble
Rotatable Bond Count 3.0
Synonyms cathaformine
Esol Class Moderately soluble
Functional Groups COC(=O)N(C)C, c1cOCO1, cO, cOC
Compound Name Cathaformine
Exact Mass 399.132
Formal Charge 0.0
Monoisotopic Mass 399.132
Hydrogen Bond Acceptor Count 7.0
Molecular Weight 399.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 1.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C21H21NO7/c1-25-15-8-12-10(7-14(15)23)6-13-16-11(4-5-22(13)21(24)27-3)18(26-2)20-19(17(12)16)28-9-29-20/h7-8,13,23H,4-6,9H2,1-3H3/t13-/m0/s1
Smiles COC1=C(C=C2C[C@H]3C4=C(CCN3C(=O)OC)C(=C5C(=C4C2=C1)OCO5)OC)O
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tyrosine alkaloids