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Thebaine N-oxide

PubChem CID: 15450568

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Compound Synonyms Thebaine N-oxide, 81600-02-4, (4R,7aR,12bS)-7,9-dimethoxy-3-methyl-3-oxido-2,4,7a,13-tetrahydro-1H-4,12-methanobenzofuro(3,2-e)isoquinolin-3-ium, (4R,7aR,12bS)-7,9-dimethoxy-3-methyl-3-oxido-2,4,7a,13-tetrahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-3-ium, Morphinan, 6,7,8,14-tetradehydro-4,5-epoxy-3,6-dimethoxy-17-methyl-, 17-oxide, (5a)-, Thebaine N-Oxide
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 45.8
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CC2CC3CCCC45C(CCCC34)CC(C1)C25
Np Classifier Class Morphinan alkaloids, Isoquinoline alkaloids
Deep Smiles COC=CC=C[C@][C@H]6Occ5cC[C@H]9[N+]CC%11))[O-])C))))ccc6OC
Heavy Atom Count 24.0
Classyfire Class Morphinans
Scaffold Graph Node Level C1CC2CC3NCCC45C(CCCC34)OC(C1)C25
Isotope Atom Count 0.0
Molecular Complexity 631.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 3.0
Iupac Name (4R,7aR,12bS)-7,9-dimethoxy-3-methyl-3-oxido-2,4,7a,13-tetrahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-3-ium
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Xlogp 1.6
Gsk 4 400 Rule True
Molecular Formula C19H21NO4
Scaffold Graph Node Bond Level C1=CC2Oc3cccc4c3C23CC[NH2+]C(C4)C3=C1
Inchi Key PMXUJDPQAVEYII-CMUWLYKVSA-N
Silicos It Class Moderately soluble
Rotatable Bond Count 2.0
Synonyms thebaine-n-oxide
Esol Class Soluble
Functional Groups COC1=CC=C(C)CC1, C[N+](C)(C)[O-], cOC
Compound Name Thebaine N-oxide
Exact Mass 327.147
Formal Charge 0.0
Monoisotopic Mass 327.147
Hydrogen Bond Acceptor Count 4.0
Molecular Weight 327.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 4.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C19H21NO4/c1-20(21)9-8-19-12-5-7-15(23-3)18(19)24-17-14(22-2)6-4-11(16(17)19)10-13(12)20/h4-7,13,18H,8-10H2,1-3H3/t13-,18+,19+,20?/m1/s1
Smiles C[N+]1(CC[C@]23[C@@H]4C(=CC=C2[C@H]1CC5=C3C(=C(C=C5)OC)O4)OC)[O-]
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tyrosine alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Papaver Somniferum (Plant) Rel Props:Reference:ISBN:9788172363130