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methyl (15R,18S,19R,20S)-18-hydroxy-14,15,16,17,18,19,20,21-octahydroyohimban-19-carboxylate

PubChem CID: 15287521

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Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 64.4
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC2CC3C(CCC4C5CCCCC5CC34)CC2C1
Np Classifier Class Yohimbine-like alkaloids
Deep Smiles COC=O)[C@H][C@@H]O)CC[C@@H][C@@H]6CcnC6)ccc-c6ncc5cccc6
Heavy Atom Count 26.0
Classyfire Class Indoles and derivatives
Scaffold Graph Node Level C1CCC2CN3CCC4C5CCCCC5NC4C3CC2C1
Classyfire Subclass Pyridoindoles
Isotope Atom Count 0.0
Molecular Complexity 555.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 4.0
Iupac Name methyl (15R,18S,19R,20S)-18-hydroxy-14,15,16,17,18,19,20,21-octahydroyohimban-19-carboxylate
Veber Rule True
Classyfire Superclass Organoheterocyclic compounds
Xlogp 2.8
Gsk 4 400 Rule True
Molecular Formula C21H22N2O3
Scaffold Graph Node Bond Level c1ccc2c3ccn4c(c-3nc2c1)CC1CCCCC1C4
Inchi Key UWMTZXSCMQAECK-RMBDZISWSA-N
Silicos It Class Moderately soluble
Rotatable Bond Count 2.0
Synonyms 3,4,5,6-tetradehydroyohimbine
Esol Class Soluble
Functional Groups CO, COC(C)=O, cn(c)C, cnc
Compound Name methyl (15R,18S,19R,20S)-18-hydroxy-14,15,16,17,18,19,20,21-octahydroyohimban-19-carboxylate
Exact Mass 350.163
Formal Charge 0.0
Monoisotopic Mass 350.163
Hydrogen Bond Acceptor Count 4.0
Molecular Weight 350.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 4.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C21H22N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,8-9,12,15,18-19,24H,6-7,10-11H2,1H3/t12-,15-,18-,19+/m0/s1
Smiles COC(=O)[C@H]1[C@H](CC[C@@H]2[C@@H]1CC3=C4C(=C5C=CC=CC5=N4)C=CN3C2)O
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tryptophan alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Rauvolfia Serpentina (Plant) Rel Props:Reference:https://doi.org/10.1186/s12906-015-0683-7