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Glabrocoumarone B

PubChem CID: 15233562

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Compound Synonyms Glyinflanin H, Glabrocoumarone B, UNII-MM2Q83EZ8W, MM2Q83EZ8W, 164123-54-0, 2H-1-Benzopyran-5-ol, 6-(6-hydroxy-2-benzofuranyl)-2,2-dimethyl-, CHEMBL233766, CHEBI:85109, 6-(6-hydroxy-1-benzofuran-2-yl)-2,2-dimethylchromen-5-ol, 6-(6-hydroxy-1-benzofuran-2-yl)-2,2-dimethyl-2H-chromen-5-ol, 6-(6-hydroxybenzofuran-2-yl)-2,2-dimethyl-2H-chromen-5-ol, DTXSID301178299, BDBM50213491, Q27158336, 6-(6-Hydroxy-2-benzofuranyl)-2,2-dimethyl-2H-1-benzopyran-5-ol, 6,2'-Dihydroxy-6'',6''-dimethylpyrano[2'',3'':4',3']-2-arylbenzofuran, 6-(6-Hydroxy-2-benzofuranyl)-2,2-dimethyl-2H-1-benzopyran-5-ol, 9CI
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 62.8
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CCC2CC(C3CC4CCCCC4C3)CCC2C1
Np Classifier Class 2-arylbenzofurans
Deep Smiles Occcccc6)occ5)cccccc6O))C=CCO6)C)C
Heavy Atom Count 23.0
Classyfire Class 2-arylbenzofuran flavonoids
Description Constituent of Glycyrrhiza glabra (licorice). Glyinflanin H is found in tea and herbs and spices.
Scaffold Graph Node Level C1COC2CCC(C3CC4CCCCC4O3)CC2C1
Isotope Atom Count 0.0
Molecular Complexity 474.0
Database Name cmaup_ingredients;fooddb_chem_all;hmdb_chem_all;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Uniprot Id P18031, n.a., Q16236, P14679
Iupac Name 6-(6-hydroxy-1-benzofuran-2-yl)-2,2-dimethylchromen-5-ol
Prediction Hob 1.0
Class 2-arylbenzofuran flavonoids
Veber Rule True
Classyfire Superclass Phenylpropanoids and polyketides
Target Id NPT178
Xlogp 4.2
Superclass Phenylpropanoids and polyketides
Gsk 4 400 Rule False
Molecular Formula C19H16O4
Scaffold Graph Node Bond Level C1=Cc2cc(-c3cc4ccccc4o3)ccc2OC1
Prediction Swissadme 0.0
Inchi Key AOVQEAUIBICOLQ-UHFFFAOYSA-N
Silicos It Class Moderately soluble
Fcsp3 0.1578947368421052
Logs -3.401
Rotatable Bond Count 1.0
State Solid
Logd 3.742
Synonyms 6-(6-Hydroxy-2-benzofuranyl)-2,2-dimethyl-2H-1-benzopyran-5-ol, 9CI, 6,2'-Dihydroxy-6'',6''-dimethylpyrano[2'',3'':4',3']-2-arylbenzofuran, Glabrocoumarone B, 6-(6-Hydroxy-2-benzofuranyl)-2,2-dimethyl-2H-1-benzopyran-5-ol, 9ci, Glabrocoumarone b, glabrocoumarone b
Substituent Name 2-arylbenzofuran flavonoid, 2,2-dimethyl-1-benzopyran, 1-benzopyran, Benzopyran, Benzofuran, Alkyl aryl ether, Benzenoid, Heteroaromatic compound, Furan, Oxacycle, Organoheterocyclic compound, Ether, Hydrocarbon derivative, Organooxygen compound, Aromatic heteropolycyclic compound
Esol Class Moderately soluble
Functional Groups cC=CC, cO, cOC, coc
Compound Name Glabrocoumarone B
Kingdom Organic compounds
Prediction Hob Swissadme 0.0
Exact Mass 308.105
Formal Charge 0.0
Monoisotopic Mass 308.105
Hydrogen Bond Acceptor Count 4.0
Molecular Weight 308.3
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 0.0
Total Bond Stereocenter Count 0.0
Molecular Framework Aromatic heteropolycyclic compounds
Lipinski Rule Of 5 True
Esol -4.814273295652175
Inchi InChI=1S/C19H16O4/c1-19(2)8-7-14-15(23-19)6-5-13(18(14)21)17-9-11-3-4-12(20)10-16(11)22-17/h3-10,20-21H,1-2H3
Smiles CC1(C=CC2=C(O1)C=CC(=C2O)C3=CC4=C(O3)C=C(C=C4)O)C
Nring 4.0
Np Classifier Biosynthetic Pathway Shikimates and Phenylpropanoids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Taxonomy Direct Parent 2-arylbenzofuran flavonoids
Np Classifier Superclass Isoflavonoids

  • 1. Outgoing r'ship FOUND_IN to/from Centella Asiatica (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Glycyrrhiza Glabra (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Glycyrrhiza Inflata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all