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4'-Demethyldehydropodophyllotoxin

PubChem CID: 15232507

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Compound Synonyms 4'-demethyldehydropodophyllotoxin, 117669-31-5, 5-hydroxy-9-(4-hydroxy-3,5-dimethoxyphenyl)-6H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one, 4 inverted exclamation mark -Demethyldehydropodophyllotoxin, 5-hydroxy-9-(4-hydroxy-3,5-dimethoxyphenyl)-6H-(2)benzofuro(5,6-f)(1,3)benzodioxol-8-one, CHEMBL521394, 4-Demethyl-Dehydropodophyllotoxin, HY-N9318, DA-60348, CS-0159381, 9-Hydroxy-5-(4-hydroxy-3,5-dimethoxyphenyl)furo[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(8H)-one
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 104.0
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC1CCC2CC3CC4CCCC4CC3C(C3CCCCC3)C12
Np Classifier Class Arylnaphthalene and aryltetralin lignans
Deep Smiles COcccccc6O))OC))))ccC=O)OCc5ccc9ccOCOc5c9)))))))))O
Heavy Atom Count 29.0
Classyfire Class Arylnaphthalene lignans
Scaffold Graph Node Level OC1OCC2CC3CC4OCOC4CC3C(C3CCCCC3)C21
Isotope Atom Count 0.0
Molecular Complexity 614.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Iupac Name 5-hydroxy-9-(4-hydroxy-3,5-dimethoxyphenyl)-6H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Lignans, neolignans and related compounds
Xlogp 3.3
Gsk 4 400 Rule True
Molecular Formula C21H16O8
Scaffold Graph Node Bond Level O=C1OCc2cc3cc4c(cc3c(-c3ccccc3)c21)OCO4
Prediction Swissadme 0.0
Inchi Key BBMUNWUDCBRTKC-UHFFFAOYSA-N
Silicos It Class Moderately soluble
Fcsp3 0.1904761904761904
Logs -4.616
Rotatable Bond Count 3.0
Logd 2.899
Synonyms 4'-o-demethyldehydropodophyllotoxin
Esol Class Moderately soluble
Functional Groups c1cOCO1, cC(=O)OC, cO, cOC
Compound Name 4'-Demethyldehydropodophyllotoxin
Prediction Hob Swissadme 0.0
Exact Mass 396.085
Formal Charge 0.0
Monoisotopic Mass 396.085
Hydrogen Bond Acceptor Count 8.0
Molecular Weight 396.3
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 0.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -4.5677520620689664
Inchi InChI=1S/C21H16O8/c1-25-15-3-9(4-16(26-2)20(15)23)17-10-5-13-14(29-8-28-13)6-11(10)19(22)12-7-27-21(24)18(12)17/h3-6,22-23H,7-8H2,1-2H3
Smiles COC1=CC(=CC(=C1O)OC)C2=C3C(=C(C4=CC5=C(C=C42)OCO5)O)COC3=O
Nring 5.0
Np Classifier Biosynthetic Pathway Shikimates and Phenylpropanoids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Lignans

  • 1. Outgoing r'ship FOUND_IN to/from Chrysosplenium Tetrandrum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Dimorphotheca Sinuata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 3. Outgoing r'ship FOUND_IN to/from Dysosma Pleiantha (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 4. Outgoing r'ship FOUND_IN to/from Dysosma Versipellis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 5. Outgoing r'ship FOUND_IN to/from Galega Officinalis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 6. Outgoing r'ship FOUND_IN to/from Peltophorum Dasyrhachis (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 7. Outgoing r'ship FOUND_IN to/from Schefflera Capitata (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 8. Outgoing r'ship FOUND_IN to/from Senecio Mexicanus (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 9. Outgoing r'ship FOUND_IN to/from Sinopodophyllum Emodi (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 10. Outgoing r'ship FOUND_IN to/from Sinopodophyllum Hexandrum (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 11. Outgoing r'ship FOUND_IN to/from Tacca Plantaginea (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 12. Outgoing r'ship FOUND_IN to/from Tecoma Grandiflora (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all