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(5S,8'R)-8'-hydroxy-6-methylspiro[7,8-dihydro-[1,3]dioxolo[4,5-g]isoquinoline-5,7'-8H-cyclopenta[g][1,3]benzodioxole]-6'-one

PubChem CID: 15070257

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Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 77.5
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule True
Scaffold Graph Level CC1C2CCC3CCCC3C2CC12CCCC1CC3CCCC3CC12
Np Classifier Class Isoquinoline alkaloids
Deep Smiles CNCCcc[C@]6C=O)cc[C@H]5O))cOCOc5cc9)))))))))))cccc6)OCO5
Heavy Atom Count 27.0
Classyfire Class Indanes
Scaffold Graph Node Level OC1C2CCC3OCOC3C2CC12NCCC1CC3OCOC3CC12
Classyfire Subclass Indanones
Isotope Atom Count 0.0
Molecular Complexity 644.0
Database Name imppat_phytochem;pubchem
Defined Atom Stereocenter Count 2.0
Iupac Name (5S,8'R)-8'-hydroxy-6-methylspiro[7,8-dihydro-[1,3]dioxolo[4,5-g]isoquinoline-5,7'-8H-cyclopenta[g][1,3]benzodioxole]-6'-one
Veber Rule True
Classyfire Superclass Benzenoids
Xlogp 1.9
Gsk 4 400 Rule True
Molecular Formula C20H17NO6
Scaffold Graph Node Bond Level O=C1c2ccc3c(c2CC12NCCc1cc4c(cc12)OCO4)OCO3
Inchi Key BQZZTMXCHPNTCL-WOJBJXKFSA-N
Silicos It Class Moderately soluble
Rotatable Bond Count 0.0
Synonyms sibiricine
Esol Class Soluble
Functional Groups CN(C)C, CO, c1cOCO1, cC(C)=O
Compound Name (5S,8'R)-8'-hydroxy-6-methylspiro[7,8-dihydro-[1,3]dioxolo[4,5-g]isoquinoline-5,7'-8H-cyclopenta[g][1,3]benzodioxole]-6'-one
Exact Mass 367.106
Formal Charge 0.0
Monoisotopic Mass 367.106
Hydrogen Bond Acceptor Count 7.0
Molecular Weight 367.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 2.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Inchi InChI=1S/C20H17NO6/c1-21-5-4-10-6-14-15(26-8-25-14)7-12(10)20(21)18(22)11-2-3-13-17(27-9-24-13)16(11)19(20)23/h2-3,6-7,19,23H,4-5,8-9H2,1H3/t19-,20-/m1/s1
Smiles CN1CCC2=CC3=C(C=C2[C@@]14[C@@H](C5=C(C4=O)C=CC6=C5OCO6)O)OCO3
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tyrosine alkaloids

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