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6-Methoxydihydrosanguinarine

PubChem CID: 14847270

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Compound Synonyms 6-Methoxydihydrosanguinarine, 72401-54-8, 6-Methoxydihydrosanguinarine72401-54-8, 23-methoxy-24-methyl-5,7,18,20-tetraoxa-24-azahexacyclo[11.11.0.02,10.04,8.014,22.017,21]tetracosa-1(13),2,4(8),9,11,14(22),15,17(21)-octaene, CHEMBL4171637, (-)-14-Methoxy-13-methyl-13,14-dihydro-[1,3]dioxolo[4',5':4,5]benzo[1,2-c][1,3]dioxolo[4,5-i]phenanthridine, 6-methoxydihydro-sanguinarine, HY-N3000, XCA40154, BDBM50286635, AKOS030524962, DA-60526, MS-25777, PD166537, CS-0022888, G60998, [1,3]Benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridine, 13,14-dihydro-14-methoxy-13-methyl-, 23-methoxy-24-methyl-5,7,18,20-tetraoxa-24-azahexacyclo[11.11.0.0(2),(1)?.0?,?.0(1)?,(2)(2).0(1)?,(2)(1)]tetracosa-1(13),2,4(8),9,11,14,16,21-octaene
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 49.4
Hydrogen Bond Donor Count 0.0
Pfizer 3 75 Rule False
Scaffold Graph Level C1CC2CC3CCC4C(CCC5C6CCCC6CCC54)C3CC2C1
Np Classifier Class Isoquinoline alkaloids
Deep Smiles COCccOCOc5ccc9-ccN%13C))cccOCOc5cc9cc%13
Heavy Atom Count 27.0
Classyfire Class Benzophenanthridine alkaloids
Scaffold Graph Node Level C1OC2CC3CCC4C5CCC6OCOC6C5CNC4C3CC2O1
Classyfire Subclass Dihydrobenzophenanthridine alkaloids
Isotope Atom Count 0.0
Molecular Complexity 575.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Uniprot Id P22303
Iupac Name 23-methoxy-24-methyl-5,7,18,20-tetraoxa-24-azahexacyclo[11.11.0.02,10.04,8.014,22.017,21]tetracosa-1(13),2,4(8),9,11,14(22),15,17(21)-octaene
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Alkaloids and derivatives
Target Id NPT204
Xlogp 4.1
Gsk 4 400 Rule False
Molecular Formula C21H17NO5
Scaffold Graph Node Bond Level c1cc2c(c3c1OCO3)CNc1c-2ccc2cc3c(cc12)OCO3
Prediction Swissadme 0.0
Inchi Key MHPDDMNAUJQRSW-UHFFFAOYSA-N
Silicos It Class Moderately soluble
Fcsp3 0.238095238095238
Logs -7.15
Rotatable Bond Count 1.0
Logd 3.361
Synonyms (-)8-methoxydihydrosanguinarine
Esol Class Moderately soluble
Functional Groups c1cOCO1, cC(OC)N(c)C
Compound Name 6-Methoxydihydrosanguinarine
Prediction Hob Swissadme 0.0
Exact Mass 363.111
Formal Charge 0.0
Monoisotopic Mass 363.111
Hydrogen Bond Acceptor Count 6.0
Molecular Weight 363.4
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 1.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -5.048406318518518
Inchi InChI=1S/C21H17NO5/c1-22-19-13(4-3-11-7-16-17(8-14(11)19)26-9-25-16)12-5-6-15-20(27-10-24-15)18(12)21(22)23-2/h3-8,21H,9-10H2,1-2H3
Smiles CN1C(C2=C(C=CC3=C2OCO3)C4=C1C5=CC6=C(C=C5C=C4)OCO6)OC
Nring 6.0
Np Classifier Biosynthetic Pathway Alkaloids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Tyrosine alkaloids

  • 1. Outgoing r'ship FOUND_IN to/from Corydalis Mucronifera (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Fumaria Indica (Plant) Rel Props:Reference:ISBN:9788171360536