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methyl (1S,14S,15R,17S,18S)-17-ethyl-5-[(1S,12S,14R,15E,18S)-15-ethylidene-18-(hydroxymethyl)-18-methoxycarbonyl-17-methyl-10,17-diazatetracyclo[12.3.1.03,11.04,9]octadeca-3(11),4,6,8-tetraen-12-yl]-14-(hydroxymethyl)-6-methoxy-3,13-diazapentacyclo[13.3.1.02,10.04,9.013,18]nonadeca-2(10),4(9),5,7-tetraene-1-carboxylate

PubChem CID: 145953141

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Compound Synonyms CHEMBL4166546
Topological Polar Surface Area 140.0
Hydrogen Bond Donor Count 4.0
Heavy Atom Count 56.0
Isotope Atom Count 0.0
Molecular Complexity 1530.0
Database Name cmaup_ingredients;pubchem
Defined Atom Stereocenter Count 9.0
Iupac Name methyl (1S,14S,15R,17S,18S)-17-ethyl-5-[(1S,12S,14R,15E,18S)-15-ethylidene-18-(hydroxymethyl)-18-methoxycarbonyl-17-methyl-10,17-diazatetracyclo[12.3.1.03,11.04,9]octadeca-3(11),4,6,8-tetraen-12-yl]-14-(hydroxymethyl)-6-methoxy-3,13-diazapentacyclo[13.3.1.02,10.04,9.013,18]nonadeca-2(10),4(9),5,7-tetraene-1-carboxylate
Prediction Hob 0.0
Xlogp 4.6
Molecular Formula C45H56N4O7
Prediction Swissadme 0.0
Inchi Key OSLAWIRDFRPQHR-DDEMAIHOSA-N
Fcsp3 0.5555555555555556
Logs -4.232
Rotatable Bond Count 9.0
Logd 4.495
Compound Name methyl (1S,14S,15R,17S,18S)-17-ethyl-5-[(1S,12S,14R,15E,18S)-15-ethylidene-18-(hydroxymethyl)-18-methoxycarbonyl-17-methyl-10,17-diazatetracyclo[12.3.1.03,11.04,9]octadeca-3(11),4,6,8-tetraen-12-yl]-14-(hydroxymethyl)-6-methoxy-3,13-diazapentacyclo[13.3.1.02,10.04,9.013,18]nonadeca-2(10),4(9),5,7-tetraene-1-carboxylate
Prediction Hob Swissadme 0.0
Exact Mass 764.415
Formal Charge 0.0
Monoisotopic Mass 764.415
Hydrogen Bond Acceptor Count 9.0
Molecular Weight 764.9
Covalent Unit Count 1.0
Total Atom Stereocenter Count 9.0
Total Bond Stereocenter Count 1.0
Esol -7.118333942857142
Inchi InChI=1S/C45H56N4O7/c1-7-24-17-26-20-44(42(52)55-5)40-29(15-16-49(41(24)44)34(26)22-50)28-13-14-35(54-4)37(39(28)47-40)31-18-32-25(8-2)21-48(3)36(45(32,23-51)43(53)56-6)19-30-27-11-9-10-12-33(27)46-38(30)31/h8-14,24,26,31-32,34,36,41,46-47,50-51H,7,15-23H2,1-6H3/b25-8-/t24-,26+,31-,32+,34+,36-,41-,44+,45-/m0/s1
Smiles CC[C@H]1C[C@@H]2C[C@@]3([C@H]1N([C@@H]2CO)CCC4=C3NC5=C4C=CC(=C5[C@@H]6C[C@@H]7/C(=C\C)/CN([C@H]([C@@]7(CO)C(=O)OC)CC8=C6NC9=CC=CC=C89)C)OC)C(=O)OC
Nring 10.0
Defined Bond Stereocenter Count 1.0