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Euphornin

PubChem CID: 14489120

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Compound Synonyms Euphornin, [(1S,2S,3aR,4S,5S,6E,9R,11R,12E,13aS)-4,9,11-triacetyloxy-3a-hydroxy-2,5,8,8,12-pentamethyl-2,3,4,5,9,10,11,13a-octahydro-1H-cyclopenta[12]annulen-1-yl] benzoate, CHEMBL499921, BDBM50468097, AKOS040734330, NCGC00384679-01, NCGC00384679-01_C33H44O9_(1S,2S,3aR,4S,5S,6E,9R,11R,12E,13aS)-4,9,11-Triacetoxy-3a-hydroxy-2,5,8,8,12-pentamethyl-2,3,3a,4,5,8,9,10,11,13a-decahydro-1H-cyclopenta[12]annulen-1-yl benzoate
Ghose Rule False
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 125.0
Hydrogen Bond Donor Count 1.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC(CC1CCC2CCCCCCCCCCC21)C1CCCCC1
Np Classifier Class Jatrophane diterpenoids
Deep Smiles CC=O)O[C@H][C@@H]C)/C=C/CC)C)[C@H]OC=O)C)))C[C@H]/C=C/[C@@H][C@]%12O)C[C@@H][C@@H]5OC=O)cccccc6)))))))))C))))))/C))OC=O)C
Heavy Atom Count 42.0
Classyfire Class Prenol lipids
Scaffold Graph Node Level OC(OC1CCC2CCCCCCCCCCC21)C1CCCCC1
Classyfire Subclass Diterpenoids
Isotope Atom Count 0.0
Molecular Complexity 1070.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 8.0
Uniprot Id P48544, Q12809
Iupac Name [(1S,2S,3aR,4S,5S,6E,9R,11R,12E,13aS)-4,9,11-triacetyloxy-3a-hydroxy-2,5,8,8,12-pentamethyl-2,3,4,5,9,10,11,13a-octahydro-1H-cyclopenta[12]annulen-1-yl] benzoate
Prediction Hob 0.0
Veber Rule True
Classyfire Superclass Lipids and lipid-like molecules
Xlogp 5.1
Gsk 4 400 Rule False
Molecular Formula C33H44O9
Scaffold Graph Node Bond Level O=C(OC1CCC2CCC=CCCCCC=CC21)c1ccccc1
Prediction Swissadme 0.0
Inchi Key BRVXVMOWTHQKHC-LKCWGRRXSA-N
Silicos It Class Moderately soluble
Fcsp3 0.5757575757575758
Logs -4.954
Rotatable Bond Count 9.0
Logd 2.84
Synonyms euphornin
Esol Class Poorly soluble
Functional Groups C/C(C)=CC, C/C=C/C, CC(=O)OC, CO, cC(=O)OC
Compound Name Euphornin
Prediction Hob Swissadme 0.0
Exact Mass 584.299
Formal Charge 0.0
Monoisotopic Mass 584.299
Hydrogen Bond Acceptor Count 9.0
Molecular Weight 584.7
Gi Absorption False
Covalent Unit Count 1.0
Total Atom Stereocenter Count 8.0
Total Bond Stereocenter Count 2.0
Lipinski Rule Of 5 True
Esol -6.215091485714287
Inchi InChI=1S/C33H44O9/c1-19-14-15-32(7,8)28(40-23(5)35)17-27(39-22(4)34)20(2)16-26-29(42-31(37)25-12-10-9-11-13-25)21(3)18-33(26,38)30(19)41-24(6)36/h9-16,19,21,26-30,38H,17-18H2,1-8H3/b15-14+,20-16+/t19-,21-,26-,27+,28+,29-,30-,33+/m0/s1
Smiles C[C@H]1C[C@]2([C@H]([C@H]1OC(=O)C3=CC=CC=C3)/C=C(/[C@@H](C[C@H](C(/C=C/[C@@H]([C@@H]2OC(=O)C)C)(C)C)OC(=O)C)OC(=O)C)\C)O
Nring 3.0
Np Classifier Biosynthetic Pathway Terpenoids
Defined Bond Stereocenter Count 2.0
Egan Rule True
Np Classifier Superclass Diterpenoids

  • 1. Outgoing r'ship FOUND_IN to/from Euphorbia Helioscopia (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all
  • 2. Outgoing r'ship FOUND_IN to/from Euphorbia Maddenii (Plant) Rel Props:Reference:ISBN:9788172362300; ISBN:9788185042114