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2,4'-Dihydroxy-4-Methoxydihydrochalcone

PubChem CID: 14157883

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Compound Synonyms 2,4'-dihydroxy-4-methoxydihydrochalcone, 3-(2-hydroxy-4-methoxyphenyl)-1-(4-hydroxyphenyl)propan-1-one, SCHEMBL4316064, CHEMBL1081513, CHEBI:180159, LMPK12120601, 98094-90-7, 1-(4-hydroxyphenyl)-3-(2-hydroxy-4-methoxyphenyl)-1-propanone
Ghose Rule True
Classyfire Kingdom Organic compounds
Topological Polar Surface Area 66.8
Hydrogen Bond Donor Count 2.0
Pfizer 3 75 Rule False
Scaffold Graph Level CC(CCC1CCCCC1)C1CCCCC1
Np Classifier Class Chalcones
Deep Smiles COcccccc6)O))CCC=O)cccccc6))O
Heavy Atom Count 20.0
Classyfire Class Linear 1,3-diarylpropanoids
Scaffold Graph Node Level OC(CCC1CCCCC1)C1CCCCC1
Classyfire Subclass Chalcones and dihydrochalcones
Isotope Atom Count 0.0
Molecular Complexity 310.0
Database Name cmaup_ingredients;imppat_phytochem;npass_chem_all;pubchem
Defined Atom Stereocenter Count 0.0
Uniprot Id n.a.
Iupac Name 3-(2-hydroxy-4-methoxyphenyl)-1-(4-hydroxyphenyl)propan-1-one
Prediction Hob 1.0
Veber Rule True
Classyfire Superclass Phenylpropanoids and polyketides
Xlogp 2.8
Gsk 4 400 Rule True
Molecular Formula C16H16O4
Scaffold Graph Node Bond Level O=C(CCc1ccccc1)c1ccccc1
Prediction Swissadme 0.0
Inchi Key RORZHTZYZDZJKG-UHFFFAOYSA-N
Silicos It Class Moderately soluble
Fcsp3 0.1875
Logs -3.391
Rotatable Bond Count 5.0
Logd 2.948
Synonyms 24-dihydroxy-4-methoxydihydrochalcone
Esol Class Soluble
Functional Groups cC(C)=O, cO, cOC
Compound Name 2,4'-Dihydroxy-4-Methoxydihydrochalcone
Prediction Hob Swissadme 0.0
Exact Mass 272.105
Formal Charge 0.0
Monoisotopic Mass 272.105
Hydrogen Bond Acceptor Count 4.0
Molecular Weight 272.29
Gi Absorption True
Covalent Unit Count 1.0
Total Atom Stereocenter Count 0.0
Total Bond Stereocenter Count 0.0
Lipinski Rule Of 5 True
Esol -3.3810599999999997
Inchi InChI=1S/C16H16O4/c1-20-14-8-4-12(16(19)10-14)5-9-15(18)11-2-6-13(17)7-3-11/h2-4,6-8,10,17,19H,5,9H2,1H3
Smiles COC1=CC(=C(C=C1)CCC(=O)C2=CC=C(C=C2)O)O
Nring 2.0
Np Classifier Biosynthetic Pathway Shikimates and Phenylpropanoids
Defined Bond Stereocenter Count 0.0
Egan Rule True
Np Classifier Superclass Flavonoids

  • 1. Outgoing r'ship FOUND_IN to/from Artemisia Dracunculus (Plant) Rel Props:Reference:https://www.ncbi.nlm.nih.gov/pubmed/17848630
  • 2. Outgoing r'ship FOUND_IN to/from Soymida Febrifuga (Plant) Rel Props:Source_db:cmaup_ingredients;npass_chem_all